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230篇 您的检索式：作者名="PEIRIS JS"

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	题名	作者	年代	出处	被引量
1	Avian influenza virus directly infects human natural killer cells and inhibits cell activity显示文摘Natural killer(NK) cell is a key component of innate immunity and plays an important role in host defense against virus infection by directly destroying infected cells. Influenza is a respiratory disease transmitted in the early phase of virus infection. Evasion of host innate immunity including NK cells is critical for the virus to expand and establish a successful acute infection. Previously,we showed that human influenza H1N1 virus infects NK cells and induces cell apoptosis, as well as inhibits NK cell activity. In this study, we further demonstrated that avian influenza virus also directly targeted NK cells as an immunoevasion strategy. The avian virus infected human NK cells and induced cell apoptosis. In addition, avian influenza virion and HA protein inhibited NK cell cytotoxicity. This novel strategy has obvious advantages for avian influenza virus, allowing the virus sufficient time to expand and subsequent spread before the onset of the specific immune response. Our findings provide an important clue for the immunopathogenesis of avian influenza,and also suggest that direct targeting NK cells may be a common strategy used by both human and avian influenza viruses to evade NK cell immunity.	Huawei Mao Yinping Liu Sin Fun Sia JS Malik Peiris Yu-Lung Lau Wenwei Tu	2017	Virologica Sinica2017，32，2：	4
2	Coronavirus as a possible cause of severe acute respiratory syndrome显示文摘	Peiris JS Lai ST Poon LL		0，，：	2
3	Emergence of a novel swine-origin influenza A virus (S-OIV) H1NI virus in humans显示文摘	Peiris JS Poon LL Guan Y	2009	J Clin Virol2009，45，3：	1
4	Coronavirus as a possible cause of severe acute respiratory syndrome显示文摘	Peiris JS Lai ST Poon LL	2003	Lancet2003，361，9366：	1
5	Avian influenza viruses in humans 显示文摘	Malik Peiris JS	2009	Rev Sci Tech2009，28，1：	1
6	Human infection with a novel Avian Influenza A (H5N6) virus 显示文摘	Yang ZF Mok CK Peiris JS	2015	N Engl J Med2015，373，5：	1
7	Avian influenza viruses in humans 显示文摘	Malik Peiris JS	2009	Rev Sci Tech2009，28，1：	1
8	Emergence of a novel swineorigin influenza A vires (S-OIV) H1N1 virus in humans 显示文摘	Peiris JS Poon LL Guan Y	2009	J Clin Virol2009，45，：	1
9	Epstein-Barr virus (EBV) infection in infancy显示文摘	Chan KH Tam JS Peiris JS	2001	J Clin Virol2001，21，1：	1
10	Avian influenza virus (H5N1):a threat to human health显示文摘	Peiris JS de Jong MD Guan Y	2007	Clin Mierobiol Rev2007，20，2：	1
11	Molecular detection of a novel human influenza (H1N1) of pandemic potential by conventional and real-time quantitative RT-PCR assays 显示文摘	Poon LL Chan KH Smith GJ Leung CS Guan Y Yuen KY Peiris JS	2009	Clin Chem2009，55，8：	1
12	Characterization of H9 subtype influenza viruses from the ducks of southern China : a candidate for the next influenza pandemic in humans? 显示文摘	Li KS Xu KM Peiris JS	2003	J Virol2003，77，12：	1
13	Coronavirus as a possible cause of severe acute respiratory syndrome显示文摘	Peiris JS Lai ST Poon LL	2003	The Lancet2003，361，9366：	1
14	Avian influenza virus (H5N1):a threat to human health 显示文摘	Peiris JS de Jong MD Guan Y	2007	Clin Microbiol Rev2007，20，2：	1
15	Emergence of a novel swine-origin in- flucnza A virus (S-OIV) HINIvirus in humans 显示文摘	Peiris JS Poon LM Guan Y	2009	J Clin Virol2009，45，3：	1
16	显示文摘	Peiris JS Lai ST Poon LL	2003	Lancet2003，361，9366：	1
17	Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia:a prospective stuty显示文摘	JS M Peiris CM Chu VC Cheng	2003	Lancet2003，361，：	1
18	Severe acute respiratory syndrome显示文摘	Peiris JS Guan Y Yuen KY	2004	Nat Med2004，10，12：	1
19	Coronavirus as a possible cause of severe acute respiratory syndrome显示文摘	Peiris JS Lai ST Poon LL	2003	Lancet2003，361，：	1
20	Epsteine Ban' virus (EBV) infection in infancy 显示文摘	Chan KH Tam JS Peiris JS	2001	J Clin Virol2001，21，1：	1

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