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| 1 | Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease显示文摘BackgroundKlotho 蛋白质(α - 并且 β) 是基于膜的传播调整细胞新陈代谢的蛋白质,以及成纤维细胞生长因素(FGF ) 的 lifespan modulating 活动。最近的数据证明了更高的血浆传播 Klotho 层次减少心血管的风险,建议 Klotho 有在心血管的疾病的一个保护的角色。然而,尽管到目前为止它在各种各样的机关被识别了,它是未知的是否,并且高心血管的风险是否能影响 Klotho 的心脏的表示 cardiomyocytes 快车 Klotho 和 FGF , FGF 和另外的 molecules.MethodsWe 与心血管的疾病和 10 匹配年龄的控制使遭到,估计的10年的低风险经历的一名估计的10年的高动脉粥样硬化患者选择了 20 个病人为除冠的动脉以外的原因的心脏的外科绕过。在心肌的活体检视,我们由免疫组织化学评估了 Klotho 和 FGF 是否在 cardiomyocytes 被表示,并且更高心血管的风险是否影响涉及 endoplasmic 蜂窝胃应力的另外的分子的表示,氧化应力,发炎并且 fibrosis.ResultsOnly ,有更高心血管的风险的病人的 cardiomyocytes 显示出 Klotho 的更低的表示,但是 FGF 的更高的表情。而且,更高心血管的风险与增加的表示被联系氧化并且网状的应力,发炎和 fibrosis.ConclusionsThis 学习的 endoplasmic 第一次证明 Klotho 蛋白质在人的 cardiomyocytes 被表示, Klotho 的那心脏的表情在更高心血管的风险病人是下面调整的,当压力相关的分子的表示显著地被增加时。 | Giovanni Corsetti Evasio Pasini Tiziano M Scarabelli Claudia Romano Pratik R Agrawal Carol Chen-Scarabelli Richard Knight Louis Saravolatz Jagat Narula Mario Ferrari-Vivaldi Vincenzo Flati Deodato Assanelli Francesco S Dioguardi | 2016 | Journal of Geriatric Cardiology2016，13，8： | 7 |
| 2 | 三级高血压单位5100例患者低血钾症与原发性醛固酮增多症的发病率显示文摘常伴有低血钾症的原发性醛固酮增多症(原醛)被认为是一个少见病。广泛筛查高血压患者发现正常血钾的原醛发生率增加。许多研究报道原醛低血钾症的发生率,相反,低血钾症患者中原醛的发生率并不明确。在该回顾性观察研究,研究者探讨了高血压患者中低钾的发生率以及低血钾症合并高血压患者中原醛的发生率。 | 赵狄(译) 刘莉(审校) Burrello J Monticone S Losano I Cavaglià G Buffolo F Tetti M Covella M Rabbia F Veglio F Pasini B Williams TA Mulatero P | 2020 | 中华高血压杂志2020，28，3： | 7 |
| 3 | On - line preconcentration/determination of copper in parenteral solutions using activated carbon by inductively coupled plasma optical emission spectrometry 显示文摘 | TAKARA E A PASINI - CABELLO S D CERUTTI S | 2005 | J Pharmaceut Biomed2005，39，34： | 1 |
| 4 | Modelling practiceal combustion systems and predicting NOx emissions with an integrated CFD based approach显示文摘 | Falcitelli M Pasini S Tognotti L | 2002 | Computers & Chemical Engineering2002，26，9： | 1 |
| 5 | Modelling practiceal combustion systems and predicting NOx emissions with an integrated CFD based approach 显示文摘 | Falcitelli M Pasini S Tognotti L | 2002 | Computers & Chemical Engineering2002，26，9： | 1 |
| 6 | CFD+ reactor network analysis: an integrated methodology for the modeling and optimisation of industrial systems for energy saving and pollution reduction 显示文摘 | Faleitelli M Pasini S Rossi N Tognotti L | 2002 | Applied Thermal Engineering2002，22，8： | 1 |
| 7 | Modelling practical combustion systems and predicting NOx emissions with an integrated CFD based approach显示文摘 | FALClTELLI M PASINI S TONGNOTTI L | 2002 | Computers and Chemical Engineering2002，26，： | 1 |
| 8 | Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow,fat,spleen and thymus显示文摘 | Krampera M Marconi S Pasini A | 2007 | Bone2007，40，2： | 1 |
| 9 | Four-Gene expression model predictive of lymph node metastases in oral squamous cell carcinoma显示文摘 | Pasini FS Maistro S Snitcovsky I | 2012 | Acta Oncologica2012，51，1： | 1 |
| 10 | Modelling,practical combustion systems and predicting NOx emissions with an integrated CFD based approach显示文摘 | FALCITELLI M PASINI S TOGNOTTI L | 2002 | Computers and Chemical Engineering2002，26，： | 1 |
| 11 | Detection of bacterial quorum sensing N-acyl homoserine lactones in clinical samples显示文摘 | Kumari A Pasini P Daunert S | 2008 | Anal Bioanal Chem2008，391，5： | 1 |
| 12 | Multi-objective optimization of a composite rotor blade cross-section显示文摘 | Visweswaraiah S B Ghiasi H Pasini D | 2013 | Composite Structures2013，96，： | 1 |
| 13 | Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus显示文摘 | KRAMPERA M MARCONI S PASINI A | 2007 | Bone2007，40，2： | 1 |
| 14 | Acoustic Pyrometer System for Tomographic Thermal Imaging in Power Plant Boilers显示文摘 | Mauro Bramanti E A S Anna Tonazzini Sauro Pasini | 1996 | IEEE Transactions on Instrument & Measurement1996，45，1： | 1 |
| 15 | Early and late results after surgical therapy of postinfarction left ventricular aneurysm显示文摘 | Pasini S Gagliardotto P Punta G | 1998 | J Cardiovasc Surg1998，39，： | 1 |
| 16 | Electroluminescent poly (fluorene-co-thiophene-S,S-dioxide):synthesis,characterisation and structure-property relationships显示文摘 | Pasini M Destri S Porzio W | 2003 | J Mater Chem2003，13，： | 1 |
| 17 | Effects of treadmill exercise and training frequency on anabolic signaling pathways in the skeletal muscle of agedrats显示文摘 | Pasini E Le Douairon Lahaye S Flati V | 2012 | Exp Gerontol2012，47，1： | 1 |
| 18 | Early and late results after surgical therapy of postinfarction left ventricular aneurysm 显示文摘 | Pasini S Gaqliardotto P Punta G | 1998 | J Cardiovasc Surg (Torino)1998，39，2： | 1 |
| 19 | Analysis of commercial wines by LC-MS/MS reveals the presence of residual milk and egg white allergens显示文摘 | TOLIN S PASINI G SIMONATO B | 2012 | Food Control2012，，2： | 1 |
| 20 | Heat stress limits infarct size in the isolated perfused rabbit heart显示文摘 | Walker DM Pasini E Kucukoglu S | | 0，，： | 1 |
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