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| 1 | Type V CRISPR-Cas Cpfl endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition显示文摘 | Pu Gao Hui Yang Kanagalaghatta R Rajashankar Zhiwei Huang Dinshaw J Patel | 2016 | Cell Research2016，26，8： | 28 |
| 2 | Targeting Tumor-Associated Macrophages by Anti-tumor Chinese Materia Medica显示文摘Tumor-associated macrophages(TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica(CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine(CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment(TME). Here we briefly summarize the pivotal effects of TAMs in shaping the TME and promoting tumorigenesis, invasion, metastasisand immunosuppression. Furthermore, we illustrate the effects and mechanisms of CMM targeting TAMs in antitumor therapy. Finally, we reveal the CMM's dual-regulatory and multi-targeting functions on regulating TAMs, and hopefully, provide the theoretical basis for CMM clinical practice related to cancer therapy. | PU Wei-ling SUN Li-kang GAO Xiu-mei Curzio Rüegg Muriel Cuendet Micheal O.Hottiger ZHOU Kun MIAO Lin ZHANG Yun-sha Margaret Gebauer | 2017 | Chinese Journal of Integrative Medicine2017，23，10： | 3 |
| 3 | Growth and properties of REBiO3 new buffer materials for coated conductors 显示文摘 | Li G Pu M H Sun R P | 2008 | Physica C2008，468，： | 1 |
| 4 | Diffusion of sucrose and yohinobine in calcium alginate gel beads with or without entrapped plant cells显示文摘 | Pu H T Yang R Y K | 1988 | Biotech Bioeng1988，32，1： | 1 |
| 5 | Orexins, a novel family of hypothalamie neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner 显示文摘 | Pu S Jain M R Kalra P S | 1998 | Regulatory Peptides1998，78，： | 1 |
| 6 | Thermal resistance of VCSEL′s bonded to integrated circuits显示文摘 | PU R WILMSEN C W GEIB K M | 1999 | IEEE Photonics Technology Letters1999，11，12： | 1 |
| 7 | Spectral absorption features as indicators of water status in coast live oak (Quercus agrifolia) leaves显示文摘 | Pu R Ge S Kell N M | 2003 | International Journal of Remote Sensing2003，24，9： | 1 |
| 8 | Extraction of red edge optical parameters from Hyperion data for estimation of forest leaf area index显示文摘 | Pu R Gong P Biging G S | 2003 | IEEE Transactions on Geoseience andRemote Sensing2003，41，： | 1 |
| 9 | Assessment of multi- resolution and multi-sensor data for urban surface temperature re- trieval显示文摘 | PU R L GONG P MICHISHITA R | 2006 | Remote Sensing of Environment2006，104，： | 1 |
| 10 | Microrna-1 negatively regulates expression of the hypertrophy-associated calmod- ulin and mef2 a genes 显示文摘 | KANG P M GOLUB T R PU W T | 2009 | Mol Cellular Biol2009，29，： | 1 |
| 11 | Coniferous forest leaf area index estimation along the Oregon transect using compact airborne spectrographic imager data 显示文摘 | Gong P Pu R Miller J R | 1995 | Photogrammetric Engineering & Remote Sensing1995，61，9： | 1 |
| 12 | Real-time vehicle navigation using a holographic memory显示文摘 | Pu A Denkewalter R Psaltis D | 1997 | Opt Eng1997，36，10： | 1 |
| 13 | Extraction of red edge optical parameters from Hyperion data for estimation of forest leaf area index显示文摘 | Pu R L Gong P Biging G S | 2003 | IEEE Transactions on Geoscience and Remote Sensing2003，41，4： | 1 |
| 14 | Pathologic features of breast cancer associated with complete response to neoadjuvant chemotherapy:importance of tumor necrosis显示文摘 | Pu R T Schott A F Sturtz D E | 2005 | Am J Surg Pathol2005，29，3： | 1 |
| 15 | Real-time vehicle navigation using a holographic memory显示文摘 | Pu A Denkewalter R Psaltis D | 1997 | Optical Engineering1997，36，10： | 1 |
| 16 | Concentrations ofendotoxins in waters around the island of montreal,and treatmentoptions显示文摘 | Gehr R Yribe PU Baptista IFDS | 2008 | Water Qual Res J Can2008，43，4： | 1 |
| 17 | Comparisons of inhibin B versus antimtlllerian hormone in poor ovarian responders undergoing in vitro fertilization 显示文摘 | Tan R Pu D Liu L | 2011 | Fertil Steril2011，96，4： | 1 |
| 18 | Conifer Species Recognition: an Rxploratory Analysis of in Situ Hyperspectral Data 显示文摘 | Pu R L Yu B | 1997 | Remote Sensing of Environment1997，62，： | 1 |
| 19 | Coniferous Forest Leaf Area Index Estimation along the Oregon Transect Using Compact Airborne Spectrographic Imager Data显示文摘 | Gong P Pu R Miller J R | 1995 | Photogrammetric Engineering and Remote Sensing1995，61，9： | 1 |
| 20 | Prediction of ultimate capacity of perforated lipped channels显示文摘 | Pu Y Godley M H R Beale R G Lau H H | 1999 | Journal of Structural Engineering1999，125，5： | 1 |
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