|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Helicobacter pylori infection and endocrine disorders:Is there a link?显示文摘Helicobacter pylori(H pylori) infection is a leading world-wide infectious disease as it affects more than half of the world population and causes chronic gastritis,peptic ulcer disease and gastric malignancies.The infection elicits a chronic cellular inflammatory response in the gastric mucosa.However,the effects of this local inflammation may not be confi ned solely to the digestive tract but may spread to involve extraintestinal tissues and/or organs.Indeed,H pylori infection has been epidemiologically linked to extra-digestive conditions and diseases.In this context,it has been speculated that H pylori infection may be responsible for various endocrine disorders,such as autoimmune thyroid diseases,diabetes mellitus,dyslipidemia,obesity,osteoporosis and primary hyperparathyroidism.This is a review of the relationship between H pylori infection and these endocrine disorders. | Konstantinos X Papamichael Garyphallia Papaioannou Helen Karga Anastasios Roussos Gerassimos J Mantzaris | 2009 | World Journal of Gastroenterology2009，15，22： | 42 |
| 2 | Primary gastric non-Hodgkin lymphomas:Recent advances regarding disease pathogenesis and treatment显示文摘Primary gastric lymphomas(PGLs)are distinct lymphoproliferative neoplasms described as heterogeneous entities clinically and molecularly.Their main histological types are diffuse large B-cell lymphoma(DLBCL)or mucosaassociated lymphoma tissue.PGL has been one of the main fields of clinical research of our group in recent years.Although gastric DLBCLs are frequent,sufficient data to guide optimal care are scarce.Until today,a multidisciplinary approach has been applied,including chemotherapy,surgery,radiotherapy or a combination of these treatments.In this minireview article,we provide an overview of the clinical manifestations,diagnosis and staging of these diseases,along with their molecular pathogenesis and the most important related clinical published series.We then discuss the scientific gaps,perils and pitfalls that exist regarding the aforementioned studies,in parallel with the unmet need for future research and comment on the proper methodology for such retrospective studies.Aiming to fill this gap,we retrospectively evaluated the trends in clinical presentation,management and outcome among 165 patients with DLBCL PGL who were seen in our institutions in 1980-2014.The study cohort was divided into two subgroups,comparing the main 2 therapeutic options[cyclophosphamide doxorubicin vincristine prednisone(CHOP)vs rituximab-CHOP(R-CHOP)].A better outcome with immunochemotherapy(R-CHOP)was observed.In the next 2 mo,we will present the update of our study with the same basic conclusion. | Michael D Diamantidis Maria Papaioannou Evdoxia Hatjiharissi | 2021 | World Journal of Gastroenterology2021，27，35： | 6 |
| 3 | Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation显示文摘AIM: To evaluate the plasma von Willebrand factor (vWF) levels in patients with ulcerative colitis (UC) and to investigate their relationship with disease activity,systemic inflammation and coagulation activation.METHODS: In 46 patients with ulcerative colitis (active in 34 patients), clinical data were gathered and plasma vWF levels, markers of inflammation (ESR, CRP, and fibrinogen) and thrombin generation (TAT, F1+2, and D-dimers) were measured at baseline and after 12 wk of treatment. Plasma vWF levels were also determined in 52 healthy controls (HC). The relationship of plasma vWF levels with disease activity, disease extent, response to therapy, acute-phase reactants (APRs) and coagulation markers (COAGs) was assessed.RESULTS: The mean plasma vWF concentrations were significantly higher in active UC patients (143.38±63.73%) than in HC (100.75±29.65%, P = 0.001)and inactive UC patients (98.92±43.6%, P = 0.031).ESR, CRP and fibrinogen mean levels were significantly higher in active UC patients than in inactive UC patients,whereas there were no significant differences in plasma levels of D-dimers, F1+2, and TAT. UC patients with raised APRs had significantly higher mean plasma vWF levels than those with normal APRs (144.3% vs 96.2%,P = 0.019), regardless of disease activity. Although the mean plasma vWF levels were higher in UC patients with raised COAGs than in those with normal COAGs,irrespective of disease activity, the difference was not significant (141.3% vs 118.2%, P = 0.216). No correlation was noted between plasma vWF levels and disease extent. After 12 wk of treatment, significant decreases of fibrinogen, ESR, F1+2, D-dimers and vWF levels were noted only in UC patients with clinical and endoscopic improvement.CONCLUSION: Our data indicate that increased plasma vWF levels correlate with active ulcerative colitis and increased acute-phase proteins. Elevated plasma vWF levels in ulcerative colitis possibly reflect an acutephase response of the perturbed endothelium due to inflammation. In UC patients, plasma vWF levels may be another useful marker of disease activity or response to therapy. | Petros Zezos Georgia Papaioannou Nikolaos Nikolaidis Themistoclis Vasiliadis Olga Giouleme Nikolaos Evgenidis | 2005 | World Journal of Gastroenterology2005，11，48： | 4 |
| 4 | Vertebral fracture assessment:Current research status and application in patients with kyphoplasty显示文摘Imaging of the spine is of paramount importance for the recognition of osteoporotic vertebral fractures(VFs), and standard radiography(SR) of the spine is the suggested diagnostic method but is not routinely used because of the cost and radiation exposure considerations. VF assessment(VFA) is an efficient, low radiation method for identifying VFs at the time of bone mineral density(BMD) measurement. Prediction models used to indicate the need for VFA may have little predictive power in subspecialty referral populations such as rheumatologic patients or patients who underwent kyphoplasty. Rheumatologic patients are frequently at increased risk for VFs, and VFA should be performed on an individual basis, also taking in account the guidelines for the general population. Kyphoplasty is a new minimal invasive procedure for the treatment of VFs and is being performed with increasing frequency. Following kyphoplasty, there may be a risk of new VFs in adjacent vertebrae. The assessment and follow-up of patients who underwent kyphoplasty requires repetitive X-ray imaging with the known limitations of SR. Thus, VFA may facilitate the evaluation of VFs in these patients because most of the kyphoplasty patients would fulfill the criteria. In a pilot study, we measured the BMD and performed VFA in 28 patients treated with kyphoplasty. Ratios of anterior to posterior(A/P) and middle to posterior(M/P) height were measured, and Genant's method was used to classify vertebrae accordingly. Intraobserver and interobserver reliability for A/P, M/P and the Genant's method were determined. Only 1 patient did not meet the criteria for VFA. Of the 364 available vertebrae, 295 could be analyzed. Most missing data(concerning 69 vertebrae) occurred in the upper thoracic region. Three of the 69 non-eligible vertebrae were lumbar vertebrae with cement leakage from the kyphoplasty procedure. In our hands, VFA was highly reproducible, demonstrating very good agreement in terms of intraobserver and interobserver reliability. Agreement was very good onthe vertebral level, 'vertebrae with kyphoplasty' level and '2 above and 1 below the kyphoplasty vertebrae'level. The application of Genant's method to these patients also resulted in perfect agreement. We believe that the potential value of VFA in patients treated with kyphoplasty requires further evaluation, particularly comparing VFA with SR and performing a longitudinal follow-up. More research will help to adopt care processes that determine which patients require VFA and how often VFA should be performed, while also considering the impact of this technique on the cost of healthcare organizations. | Efstathios Drampalos Konstantinos Nikolopoulos Christos Baltas Alexia Balanika Antonis Galanos Nikolaos Papaioannou Spyros Pneumaticos | 2015 | World Journal of Orthopedics2015，6，9： | 4 |
| 5 | Two-dimensional control of light with light on metasurfaces显示文摘The ability to control the wavefront of light is fundamental to focusing and redistribution of light,enabling many applications from imaging to spectroscopy.Wave interaction on highly nonlinear photorefractive materials is essentially the only established technology allowing the dynamic control of the wavefront of a light beam with another beam of light,but it is slow and requires large optical power.Here we report a proof-of-principle demonstration of a new technology for two-dimensional(2D)control of light with light based on the coherent interaction of optical beams on highly absorbing plasmonic metasurfaces.We illustrate this by performing 2D all-optical logical operations(AND,XOR and OR)and image processing.Our approach offers diffractionlimited resolution,potentially at arbitrarily-low intensity levels and with 100 THz bandwidth,thus promising new applications in space-division multiplexing,adaptive optics,image correction,processing and recognition,2D binary optical data processing and reconfigurable optical devices. | Maria Papaioannou Eric Plum João Valente Edward TF Rogers Nikolay I Zheludev | 2016 | Light(Science & Applications)2016，5，1： | 3 |
| 6 | Laparoscopic common bile duct exploration after failed endoscopic stone extraction显示文摘 | Constantine Karaliotas George Sgourakis Constantine Goumas Nickolaos Papaioannou Constantine Lilis Emmanouel Leandros | 2008 | Surgical Endoscopy2008，，8： | 2 |
| 7 | Hyperhomocysteinemia in ulcerative colitis is related to folate levels显示文摘AIM: To study the prevalence and clinical significance of hyperhomocysteinemia (hHcys), an independent factor for arterial and venous thrombosis, in a group of patients with ulcerative colitis (UC).METHODS: Fasting homocysteine (Hcys), folate, and vitamin B12 serum levels were measured in 40 UC patients and 50 healthy controls. Clinical data regarding UC were gathered.RESULTS: Median serum Hcys levels in UC patients were similar to those in controls (12.26 μmol/L vs 12.32 μmol/L), but the prevalence of hHcys was higher in UC patients than in controls (30% vs 10%, P= 0.028). UC significantly increased the risk of hHcys (adjusted odds ratio: 4.125;95% CI: 1.26-13.44). Multivariate regression analysis showed that male sex, folate and vitamin B12 deficiency or lower serum values were significant independent predictors of higher Hcys levels in UC patients (r2 = 0.4; P<0.001).CONCLUSION: hHcys is common in UC patients and it is related to folate and vitamin B12 deficiency or lower serum values. It would be reasonable for patients with UC to receive folate and vitamin B complex supplements as a prophylactic measure. | Petros Zezos Georgia Papaioannou Nikolaos Nikolaidis Themistoclis Vasiliadis Olga Giouleme Nikolaos Evgenidis | 2005 | World Journal of Gastroenterology2005，11，38： | 2 |
| 8 | Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B显示文摘 | Emanuel K. Manesis George V. Papatheodoridis Dina G. Tiniakos Emilia S. Hadziyannis Olga P. Agelopoulou Thalia Syminelaki Christos Papaioannou Theodoros Nastos Peter Karayiannis | 2010 | Journal of Hepatology2010，，1： | 2 |
| 9 | An evaluation of accelerated Portland cement as a restorative material显示文摘 | ABDUUAH D PITT FORD TR PAPAIOANNOU S | 2002 | Biomater2002，23，： | 1 |
| 10 | Heart rate effect on he modynamics during mechanical assistance by the intro-aortic balloon pump显示文摘 | PAPAIOANNOU T D TERROVITIS J | 2002 | Int J Artif Organs2002，25，12： | 1 |
| 11 | Oral L-arginine improves endothelial dysfunction in patients with essential hypertension显示文摘 | Lekakis JP Papathanassiou S Papaioannou TG | 2002 | Int J Cardiol2002，86，23： | 1 |
| 12 | Diagnostic and therapeutic value of selective salpingography and tubal catheterization in an unselected infertile population显示文摘 | Papaioannou S Afnan M Girling AJ | 2003 | Fertil Steril2003，79，3： | 1 |
| 13 | The role of natural and synthetic zeolites as feed additives on the prevention and/or the treatment of certain farm animal disease:A review 显示文摘 | PAPAIOANNOU D KASTSOULOS P D PANOUSIS N | 2005 | Microporous and Mesoporous Materials2005，84，13： | 1 |
| 14 | The association of metabolic syndrome with adipose tissue hormones and insulin resistance in patients with COPD without co- morbidities显示文摘 | Minas M Kostikas K Papaioannou AI Mystridou P Karetsi E Georgoulias P Liakos N Pournaras S Gourgoulianis KI | 2011 | COPD2011，8，6： | 1 |
| 15 | A hypothesis for the pathogenesis and natu-ral history of proximal tubal blockage 显示文摘 | Papaioannou S | 2004 | Hum Reprod2004，19，3： | 1 |
| 16 | Acute effects of caffeine on arterial stiffness, wave reflections, and central aortic pressures显示文摘 | Theodoros G. Papaioannou Kalliopi Karatzi Emmanouil Karatzis Christos Papamichael John P. Lekakis | 2005 | American Journal of Hypertension2005，，1： | 1 |
| 17 | Preparation and characterization of the inclusion complex offurosemide with hydroxypropyl-beta-cyclodextrin显示文摘 | Vlachou M Papaioannou G | 2003 | J Biomater Appl2003，17，3： | 1 |
| 18 | Ratio of PAR to broadband solar radiation measured in Cyprus显示文摘 | JACOVIDES C P TIMVIOS F S PAPAIOANNOU G | 2004 | Agricultural and Forest Meteorology2004，121，34： | 1 |
| 19 | Cre activity causes widespread ap optosis and lethal anemia during embryonic development 显示文摘 | Naiche LA Papaioannou VE | 2007 | Genesis2007，45，12： | 1 |
| 20 | Residual pleural thickening is related to vascular endothelial growth factor levels in parapneumonic pleural effusions显示文摘 | Papaioannou A I Kostikas K Tsopa P | 2010 | Respiration2010，80，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员