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| 1 | Gastroesophageal reflux: the features in elderlypatients显示文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients. | Huang X Zhu HM Deng CZ Porro GB Sangaletti O Pace F | 1999 | World Journal of Gastroenterology1999，5，5： | 12 |
| 2 | Gastroesophageal reflux and Helicobacter pylori:a review显示文摘INTRODUCTION Since the observation by Labenz et al thateradication of Helicobacter pylori(Hp)infectionmay be followed by development of refluxesophagitis in a relevant proportion of duodenalulcer patients previously not affected bygastroesophageal reflux disease(GERD),agrowing attention has been given to the | F Pace G Bianchi Porro | 2000 | World Journal of Gastroenterology2000，6，3： | 6 |
| 3 | Pathogenetic factors affecting gastroesophageal refluxin patients with esophagitis and concomitant duodenal ulcer:a multivariate analysis显示文摘Pathogeneticfactorsafectinggastroesophagealrefluxinpatientswithesophagitisandconcomitantduodenalulcer:amultivariateanalysisZH... | Zhu, HM Huang, X Deng, CZ Porro, GP Pace, F Sangaletti, O | 1998 | World Journal of Gastroenterology1998，4，2： | 2 |
| 4 | Gastric acid secretion and pattern of astroesophageal reflux in patients with esophagitis and concomitant duodenal ulcer显示文摘 | Zhu H Pace F Sangaletti O | 1993 | Scand J Gastroenterol1993，28，5： | 1 |
| 5 | The neurobiology of sleep: Genetic, cellular physiology and subcortical networks显示文摘 | PACE S E F HOBSON J A | 2002 | Nat Rev Neurosci2002，3，8： | 1 |
| 6 | Gastroesophageal reflux disease:a typical spectrum disease (a new conceptual framework is not needed ) 显示文摘 | Pace F Porro GB | 2004 | Am J Gastroenterol2004，99，5： | 1 |
| 7 | Features of symptomatic gastroesophageal reflux in elderly patients 显示文摘 | Zhu H Pace F Sangaletti O | 1993 | Scand J Gastroenterol1993，28，3： | 1 |
| 8 | A five-year retro-spective study of the epidemiological characteristics andvisual outcomes of patients hospitalized for ocular traumain a Mediterranean area显示文摘 | Cillino S Casuccio A Di Pace F | 2008 | BMC Ophthalmology2008，8，： | 1 |
| 9 | A new method to obtain good anatomical slides of heterogeneous plant parts显示文摘 | BARBOSA A C F PACE M R WITOVISK L | 2010 | IAWA Journal2010，31，4： | 1 |
| 10 | Deep sclerectomy versus trabeculectomy with low-dosage mitomycin C:four year follow-up显示文摘 | Cillino S Di Pace F Casuccio A | | 0，，： | 1 |
| 11 | Rabeprazole: a second-generation proton pump inhibitor in the treatment of acid-related disease显示文摘 | Pallotta S Pace F Marelli S | 2008 | Expert Rev Gastroenterol Hepatol2008，2，4： | 1 |
| 12 | Outcome research in gastroenterology: the case of gastroesophageal reflux disease (GERD)显示文摘 | Pace F Molteni P Wiklund I | 2006 | Drug Develop Res2006，67，3： | 1 |
| 13 | Spatial statistics and real estate显示文摘 | PACE R KEKKEY RONALD BARRY C F SIRMANS | 1998 | Journal of Real Estate Finance and E conomics1998，17，1： | 1 |
| 14 | Cytokine - effects on glucocorticoid receptor function:Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression 显示文摘 | Pace TW Hu F Miller AH | 2007 | Brain Behav Immun2007，21，1： | 1 |
| 15 | Prevalence and clinical features of heterotopic gastyic mucosa in the upper oesophagus显示文摘 | Maconi G Pace F Vago L | 2000 | Eur J Gastroenterol Hepatol2000，12，： | 1 |
| 16 | Cytokine-effects on glucocorticoid receptor function:Relevance to glucocorticoid resistance and the pathophysiology and treatment of major dep ression显示文摘 | Pace TW Hu F MillerAH | 2007 | B-rain B ehav Imm un2007，21，1： | 1 |
| 17 | Zebra mussel invasion in a large, turbid river: Phytoplankton response to increased grazing 显示文摘 | Caraco N F Cole J J Raymond P A Strayer D L Pace M L Findlay Stuart E G Fischer D T | 1997 | Ecology1997，78，2： | 1 |
| 18 | Management of the Schatzker VI fractures with lateral locked screw plating显示文摘 | Spagnolo R Pace F | 2012 | Musculoskelct Surg2012，96，2： | 1 |
| 19 | Phylogenetic stains:ribosomal RNA-based probes for the identification of single cells显示文摘 | Delong E F Wiekham G S Pace N R | 1989 | Science1989，243，： | 1 |
| 20 | Outcome research in gastroenter-ology: the case of gastroesophageal reflux disease (GERD) 显示文摘 | Pace F Moheni P Wiklund L | 2006 | Drug Develop Res2006，67，3： | 1 |
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