| 1 | Use of antibacterial sutures for skin closure in controlling surgical site infections: a systematic review of published randomized, controlled trials显示文摘Objective:The objective of this article is to systematically analyse the randomized,controlled trials that compare the use of antibacterial sutures(ABS)for skin closure in controlling surgical site infections.Methods:Randomized,controlled trials on surgical patients comparing the use of ABS for skin closure in controlling the surgical site infections were analysed systematically using RevMan^(■)and combined outcomes were expressed as odds ratios(OR)and standardized mean differences(SMD).Results:Seven randomized,controlled trials evaluating 1631 patients were retrieved from electronic databases.There were 760 patients in the ABS group and 871 patients in the simple suture group.There was moderate heterogeneity among trials(Tau^(2)=0.12;chi^(2)=8.40,df=6[P<0.01];I^(2)=29%).Therefore in the random-effects model,the use of ABS for skin closure in surgical patients was associated with a reduced risk of developing surgical site infections(OR,0.16;95%CI,0.37,0.99;z=2.02;P<0.04)and postoperative complications(OR,0.56;95%CI,0.32,0.98 z=2.04;P=0.04).The durations of operation and lengths of hospital stay were similar following the use of ABS and SS for skin closure in patients undergoing various surgical procedures.Conclusion:Use of ABS for skin closure in surgical patients is effective in reducing the risk of surgical site infection and postoperative complications.ABS is comparable with SS in terms of length of hospital stay and duration of operation. | Muhammad S.Sajid L.Craciunas P.Sains K.K.Singh M.K.Baig | 2013 | Gastroenterology Report2013，1，1： | 0 |
| 2 | Open transinguinal preperitoneal mesh repair of inguinal hernia:a targeted systematic review and meta-analysis of published randomized controlled trials显示文摘Objective:The objective of this article is to systematically analyse the randomized,controlled trials comparing transinguinal preperitoneal(TIPP)and Lichtenstein repair(LR)for inguinal hernia.Methods:Randomized,controlled trials comparing TIPP vs LR were analysed systematically using RevMan®and combined outcomes were expressed as risk ratio(RR)and standardized mean difference.Results:Twelve randomized trials evaluating 1437 patients were retrieved from the electronic databases.There were 714 patients in the TIPP repair group and 723 patients in the LR group.There was significant heterogeneity among trials(P<0.0001).Therefore,in the random effects model,TIPP repair was associated with a reduced risk of developing chronic groin pain(RR,0.48;95%CI,0.26,0.89;z=2.33;P<0.02)without influencing the incidence of inguinal hernia recurrence(RR,0.18;95%CI,0.36,1.83;z=0.51;P=0.61).Risk of developing postoperative complications and moderate-to-severe postoperative pain was similar following TIPP repair and LR.In addition,duration of operation was statistically similar in both groups.Conclusion:TIPP repair for inguinal hernia is associated with lower risk of developing chronic groin pain.It is comparable with LR in terms of risk of hernia recurrence,postoperative complications,duration of operation and intensity of postoperative pain. | Muhammad S.Sajid L.Craciunas K.K.Singh P.Sains M.K.Baig | 2013 | Gastroenterology Report2013，1，2： | 0 |
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