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| 1 | Hepatitis B and immunosuppressive therapies for chronic inflammatory diseases: When and how to apply prophylaxis, with a special focus on corticosteroid therapy显示文摘Currently immunosuppressive and biological agentsare used in a more extensive and earlier way in patients with inflammatory bowel disease, rheumatic or dermatologic diseases. Although these drugs have shown a significant clinical benefit, the safety of these treatments is a challenge. Hepatitis B virus(HBV) reactivations have been reported widely, even including liver failure and death, and it represents a deep concern in these patients. Current guidelines recommend to preemptive therapy in patients with immunosuppressants in general, but preventive measures focused in patients with corticosteroids and inflammatory diseases are scarce. Screening for HBV infection should be done at diagnosis. The patients who test positive for hepatitis B surface antigen, but do not meet criteria for antiviral treatment must receive prophylaxis before undergoing immunosuppression, including corticosteroids at higher doses than prednisone 20 mg/d during more than two weeks. Tenofovir and entecavir are preferred than lamivudine because of their better resistance profile in long-term immunosuppressant treatments. There is not a strong evidence, to make a general recommendation on the necessity of prophylaxis therapy in patients with inflammatory diseases that are taking low doses of corticosteroids in short term basis or low systemic bioavailability corticosteroids such as budesonide or beclomethasone dipropionate. In these cases regularly HBV DNA monitoring is recommended, starting early antiviral therapy if DNA levels begin to rise. In patients with occult or resolved hepatitis the risk of reactivation is much lower, and excepting for Rituximab treatment, the prophylaxis is not necessary. | Pilar López-Serrano Elsa de la Fuente Briongos Elisa Carrera Alonso Jose Lázaro Pérez-Calle Conrado Fernández | 2015 | World Journal of Hepatology2015，7，3： | 4 |
| 2 | Analytical validation of commercially available methods for acute phase proteins quantification in pigs显示文摘 | Tecles F Fuentes P Subiela S M | 2007 | Res Vet Sci2007，83，： | 1 |
| 3 | Evaluation of a new co- mputer-assisted surgical planning and navigation system based on two--dimensional fluoroscopy for insertion of a proximal fem- oral nail: an experimental study显示文摘 | Muller M Belei P de la Fuente M | 2011 | Proc Inst Mech Eng H2011，225，5： | 1 |
| 4 | Individual differences in the Behavioral Inhibition System are associated with orbitofrontal cortex and precuneus gray matter volume 显示文摘 | Fuentes P Barros-Loscertales A Bustamante J C | 2012 | Cogn Affect Behav Neurosci2012，12，3： | 1 |
| 5 | Efficacy of intra-venous thrombolysis according to stroke subtypes: the Ma- drid Stroke Network data显示文摘 | FUENTES B EGIDO J SIMAL P | 2012 | Eur J Neurol2012，19，12： | 1 |
| 6 | Pectin esterase gene family in strawberry fruit:study of FaPE1, a ripening-specific isoform显示文摘 | Castillejo C de la Fuente J I Iannetta P | 2004 | J Exp Bot2004，55，398： | 1 |
| 7 | Sefety of inducing sputum in patients with asthma of varing severity显示文摘 | Romagmoli M Gocard P | 1998 | Am J Respir Crit Care Med1998，157，3： | 1 |
| 8 | Open kyphoplasty for man- agement of severe osteoporotic spinal fractures 显示文摘 | Fuentes S Blondel B Mctellus P | 2009 | Neurosurgery2009，64，52： | 1 |
| 9 | DDT induces apoptosis in human mononuclear cells in vitro and is associated with increased apoptosis in exposed children 显示文摘 | Pérez-Maldonado IN D??az-Barriga F de la Fuente H González-Amaro R Calderón J Yá?ez L | 2004 | Environ Res2004，94，1： | 1 |
| 10 | Direct sequence spread spectrum radio LANs显示文摘 | | 1995 | IEEE Colloquium (Digest)1995，71，4： | 1 |
| 11 | Open kyphoplas-ty for management of metastatic and severe osteoporotic spinalfracture:technical note显示文摘 | Fuentes S Metellus P Pech-Gourg G | 2007 | J Neurosurg Spine2007，6，3： | 1 |
| 12 | The effects of silver nitrate and different carbohydrate sources on somatic embryogenesis in coffea canephora显示文摘 | Fuentes S L Calheiros M P Manetti-Filho J | 2000 | Plant Cell Tiss Org Cult2000，60，： | 1 |
| 13 | Safety of inducing sputum in patients with asthma of varying severity显示文摘 | Dela Fuente PT Romagnoli M Godard P | 1998 | Am J Respir Crit Care Med1998，157，11： | 1 |
| 14 | Pectin esterase gene family in strawberry fruit:study of FaPE1,a ripening-specific isoform显示文摘 | CASTILLEJO C DE LA FUENTE J I IANNETTA P BOTELLA M A VALPUESTA V | 2004 | J Exp Bot2004，55，398： | 1 |
| 15 | Characterization of sex chromosomes in rainbow trout and coho salmon using fluorescence in situ hybridization ( FISH ) 显示文摘 | Iturra P Lam N de la Fuente M | 2001 | Genetica2001，111，13： | 1 |
| 16 | Overexpression of follistatin in trout stimulates increased muscling显示文摘 | Medeiros E F Phelps M P Fuentes F D | 2009 | American Journal of Physiology-regulatory Integrative and ComparativePhysiology2009，297，： | 1 |
| 17 | Fish Freshness Decay Measurement with a Colorimetric Array显示文摘 | Zaragoz~ P Ribes S Fuentes A | 2012 | Procedia Engineering2012，47，： | 1 |
| 18 | Indi-vidual differences in the Behavioral Inhibition System areassociated with orbitofrontal cortex and precuneus gray mat-ter volume显示文摘 | Fuentes P Barros-Loscertales A Bustamante JC | 2012 | Cogn Affect Behav Neurosci2012，12，3： | 1 |
| 19 | The origin of cor- relations in metabolomics data显示文摘 | Camacho D De La Fuente A Mendes P | 2005 | Metabolomics2005，1，1： | 1 |
| 20 | Percutaneous kyphoplas-ty and pedicle screw fixation for the management of thoraco-lum-bar burst fractures 显示文摘 | Fuentes S Blondel B Metellus P | 2010 | Eur Spine J2010，19，8： | 1 |
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