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| 1 | ARNI and SGLT2i: a promising association to be used with caution显示文摘During the last years, several pharmacological treatments have significantly improved outcome of patients with heart failure with reduced ejection fraction(HFr EF) particularly by inhibiting the renin–angiotensin–aldosterone system(RAAS) and by blocking the sympathetic system.[1,2] More recently, it was demonstrated that a further positive neurohormonal modulation of RAAS and of the natriuretic peptides pathway with Sacubitril/Valsartan(Sa/Va). | Andrea Herbst Francesco Orso Marta Migliorini Simona Virciglio Silvia Tognelli Viola Camartini Alessandra Pratesi Francesco Fattirolli NiccolòMarchionni Andrea Ungar Samuele Baldasseroni | 2020 | Journal of Geriatric Cardiology2020，17，11： | 2 |
| 2 | The power of microRNAs as diagnostic and prognostic biomarkers in liquid biopsies显示文摘In the last decades,progresses in medical oncology have ameliorated the treatment of patients and their outcome.However,further improvements are still necessary,in particular for certain types of tumors such as pancreatic,gastric,and lung cancer as well as acute myeloid leukemia where early detection and monitoring of the disease are crucial for final patient outcome.Liquid biopsy represents a great advance in the field because it is less invasive,less time-consuming,and safer compared to classical biopsies and it can be useful to monitor the evolution of the disease as well as the response of patients to therapy.Liquid biopsy allows the detection of circulating tumor cells,nucleic acids,and exosomes not only in blood but also in different biological fluids:urine,saliva,pleural effusions,cerebrospinal fluid,and stool.Among the potential biomarkers detectable in liquid biopsies,microRNAs(miRNAs)are gaining more and more attention,since they are easily detectable,quite stable in biological fluids,and show high sensitivity.Many data demonstrate that miRNAs alone or in combination with other biomarkers could improve the diagnostic and prognostic power for many different tumors.Despite this,standardization of methods,sample preparation,and analysis remain challenging and a huge effort should be made to address these issues before miRNA biomarkers can enter the clinic.This review summarizes the main findings in the field of circulating miRNAs in both solid and hematological tumors. | Lorena Quirico Francesca Orso | 2020 | Cancer Drug Resistance2020，3，2： | 2 |
| 3 | microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression 显示文摘 | Dentelli P Rosso A Orso F etal | 2010 | Arterioscler Thromb Vasc Biolj2010，30，8： | 1 |
| 4 | Unusual onset of venous thromboembolism and heparin-induced thrombocytopenia in a patient with essential thrombocythemia显示文摘 | Mario Lapecorella Alessandro Lucchesi Mauro Di Ianni Mariasanta Napolitano Gino Coletti Gabriella Di Leonardo Luigi Dell?Orso Remo Barnabei Guglielmo Mariani | 2010 | Blood Coagulation & Fibrinolysis2010，，1： | 1 |
| 5 | Regulation of scaven- ger receptor CD163 expression in human monocytes and macrophages by pro- and antiinfiammatory stimuli 显示文摘 | Buechler C Ritter M Orso E | 2000 | J Leukoc Biol2000，67，： | 1 |
| 6 | Adiponectin in outpatients with coronary artery disease: independent predictors and relationship with heart failure显示文摘 | Baldasseroni S Mannucci E Orso F | 2012 | Nutr Metab Cardiovasc Dis2012，22，3： | 1 |
| 7 | Adiponectin in outpatients with coronary artery disease : independent predictors and relationship with heart failure 显示文摘 | Baldasseroni S Mannucci E Orso F | 2012 | Nutr Metab Cardiovasc Dis2012，22，3： | 1 |
| 8 | The execution of the transcriptional axismutant p53, E2F1 and ID4 promotes tumor neo -angiogenesis显示文摘 | Fontemaggi G Dell Orso S Trisciuoglio D | 2009 | Nat Struet Mol Biol2009，6，10： | 1 |
| 9 | Heart rate in coronary syndromes and heart failure 显示文摘 | Orso F Baldasseroni S Maggioni AP | 2009 | Prog Cardiovasc Dis2009，52，1： | 1 |
| 10 | Improving penetration testing through static and dynamic analysis显示文摘 | William G J Halfond Shauvik Roy Choudhary Alessandro Orso | 2011 | Software Testing Verifieation&Reliability2011，21，3： | 1 |
| 11 | MicroRNA -214 contributes to melanoma tumour progression through suppression of TFAP2C显示文摘 | Penna E Orso F Cimino D Tenag|ia E Lembo A Quaglino E Poliseno L Haimovic A Osella-Abate S De Pitta C Pinatel E Stadler M B Provero P Bemengo M G Osman I Taverna D | 2011 | EMBO Journal2011，30，10： | 1 |
| 12 | The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease显示文摘 | Bodzioch M Orso E Klucken J | 1999 | Nat Genet1999，22，： | 1 |
| 13 | Impact of comprehensive pulmonary rehabilitation on anxiety and depression in hospitalized COPD patients 显示文摘 | Garuti G Cilione C Dell 'orso D | 2008 | Monaldi Arch Chest Dis2008，59，1： | 1 |
| 14 | The gene encoding ATP- binding cassette transporter 1 is mutated in Tangier disease显示文摘 | Bodzioch M Orso E Klucken J | 1999 | Nat Genet1999，22，4： | 1 |
| 15 | Regulation of scavenger recep?tor CD]63 expression itt human monocytes and macrophages by pro?and antiinflammatory stimuli 显示文摘 | Buechler C Ritter M Orso E | 2000 | J Leukoc BioI2000，67，： | 1 |
| 16 | Tat aeetylation modulates assembly of a viral-host RNA-protein transcription complex 显示文摘 | D'Orso I Frankel AD | 2009 | Proe Natl Acad Sci US A2009，106，9： | 1 |
| 17 | The gene coding ATP-binding cassette transporter 1 is mutated in Tangier disease 显示文摘 | Bodzioch M Orso E Klucken J | 1999 | Nat Genet1999，22，4： | 1 |
| 18 | Regulation of scavenger receptor CD 163 in human monocyte and macrophages by pro-and antiimflammatory stimuli显示文摘 | Buechler C Ritter M Orso E | 2000 | J Leukoc Biol2000，67，1： | 1 |
| 19 | Impact of comprehensive pulmonary rehabilitation on anxiety and depression in hospitalized COPD patients显示文摘 | Garuti G Cilione C Dell'Orso D | 2003 | Monaldi Arch Chest Dis2003，59，1： | 1 |
| 20 | Impact of comprehensive pulmonary rehabilitation on anxiety and depression in hospitalized COPD patients显示文摘 | Garuti G Cilione C Dell'orso D | 2003 | Monaldi Arch Chest Dis2003，59，1： | 1 |
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