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| 1 | Clinical analysis of propofol deep sedation for 1,104 patients undergoing gastrointestinal endoscopic procedures:A three year prospective study显示文摘瞄准:在经历 gastros 拷贝和结肠镜检查的病人上分析 propofol 的血液动力学、呼吸的效果。方法:在这未来的研究,在三年的一个时期上进行了, 1,104 个病人参考了一一样的天官方补给的内视镜检查法过程被分析。所有病人被给一丸 propofol 大丸药(0.5-1.5 mg/kg ) 。动脉的血压(BP ) 在 3 min 间隔和心搏率被监视,氧饱和(SpO2 ) 被脉搏血氧定量法连续地记录。分析数据获得以前被执行,在期间,并且在过程以后。结果:在吝啬的动脉压的统计上重要的减小被表明(P <
0.001 ) 什么时候与干预前价值,而是严重低血压相比,在 60 毫米汞柱下面定义为收缩血压,在仅仅 5 个病人(0.5%) 被注意。氧饱和从 96.5% ~ 94.4 % 减少了(P <
0.001 ) 。在氧饱和的批评减少(<
90%) 在 27 个病人(2.4%) 被记录。结论:如果小心地滴定,我们的结果证明 propofol 向好镇静提供了优秀疼痛控制,短复原时间和没有重要血液动力学的副作用。所有病人(并且特别 ASA III 组) 要求监视并且一个麻醉学者关心。 | Stojanka Gaparovi Nadan Rustemovi Milorad Opai Marina Premuzi Andelko Korui Jadranka Bozikov Tamara Bates | 2006 | World Journal of Gastroenterology2006，12，2： | 41 |
| 2 | Endoscopic ultrasound elastography strain histograms in the evaluation of patients with pancreatic masses显示文摘AIM: To investigate the accuracy of the strain histogram endoscopic ultrasound(EUS)-based method for the diagnostic differentiation of patients with pancreatic masses. METHODS: In a prospective single center study, 149 patients were analyzed, 105 with pancreatic masses and 44 controls. Elastography images were recorded using commercially available ultrasound equipment in combination with EUS linear probes. Strain histograms(SHs) were calculated by machine integrated software in regions of interest and mean values of the strain histograms were expressed as Mode 1(over the mass) and Mode 2(over an adjacent part of pancreatic tissue, representing the reference area). The ratio between Mode 2 and Mode 1 was calculated later, representing a new variable, the strain histogram ratio. After the final diagnosis was established, two groups of patients were formed: a pancreatic cancer group with positive cytology achieved by fine needle aspiration puncture or histology after surgery(58 patients), and a massforming pancreatitis group with negative cytology and follow-up after 3 and 6 mo(47 patients). All statistical analyses were conducted in SPSS 14.0(SPSS Inc., Chicago, IL, United States).RESULTS: Results were obtained with software for strain histograms with reversed hue scale(0 represents the hardest tissue structure and 255 the softest). Based on the receiver operating characteristics(ROC) curve coordinates, the cut-off point for Mode 1 was set at the value of 86. Values under the cut-off point indicated the presence of pancreatic malignancy. Mode 1 reached 100% sensitivity and 45% specificity with overall accuracy of 66%(95%CI: 61%-66%) in detection of pancreatic malignant tumors among the patients with pancreatic masses. The positive and negative predictive values were 54% and 100%, respectively. The cut-off for the new calculated variable, the SH ratio, was set at the value 1.153 based on the ROC curve coordinates. Values equal or above the cut-off value were indicative of pancreatic malignancy. The SH ratio reached 98% sensitivity, 50% specificity and an overall accuracy of 69%(95%CI: 63%-70%). The positive and negative predictive values were 92% and 100%, respectively.CONCLUSION: SH showed high sensitivity in pancreatic malignant tumor detection but disappointingly low specificity. Slight improvements in specificity and accuracy were achieved using the SH ratio. | Dalibor Opa?i? Nadan Rustemovi? Mirjana Kalauz Pave Marko? Zvonimir Ostoji? Matea Majerovi? Iva Ledinsky Ana Vi?nji? Juraj Krznari? Milorad Opa?i? | 2015 | World Journal of Gastroenterology2015，21，13： | 3 |
| 3 | Calretieulin, a Ca^2-binding chaperone of the endoplasmic reticulum 显示文摘 | Gelebart P Opas M Miehalak M | 2005 | The International Journal of Biochemistry & Cell Biology (IJBCB)2005，37，： | 1 |
| 4 | Development of cytochalasin B-induced tetraploid and diploid/tetraploid mosaic mouse embryos 显示文摘 | TARKOWSKI A K WlTKOWSKA A OPAS J | 1977 | J Embryol Exp Morphol1977，41，： | 1 |
| 5 | Prostaglandin E2-bisphosphonate conjugates:potential agents for treatment of osteoporosis显示文摘 | Gil L Han Y Opas E E | 1999 | Bioorg Med Chem1999，7，： | 1 |
| 6 | Calreticulin: not just another calcium-binding protein 显示文摘 | Nash PD Opas M Michalak M | 1994 | Mol Cell Biochem1994，135，1： | 1 |
| 7 | A Modified Hough Transformation for Line Detection and Its Performance显示文摘 | Opas Chutatape Linfeng Guo | 1999 | Pattern Recognition1999，32，2： | 1 |
| 8 | Preliminary linkage map of the chicken genome based on microsatellite markers:77 new markers mapped显示文摘 | Crooijmans RP Van OPA | 1996 | Poult Sci1996，75，6： | 1 |
| 9 | Information tech- nologies and business value- An analytic and empirical investigation 显示文摘 | BARUA A KRIEBEL C H MUKH OPA D T | 1995 | Information Systems Research1995，6，1： | 1 |
| 10 | The ins and outs of ealreticulin: From the ER lumen to the extracellular space 显示文摘 | Johnson S Michalak M Opas M | 2001 | Trends in Cell Biology2001，11，： | 1 |
| 11 | Adhesiveness and proliferation of epithelial cells are differentially modulated by activation and inhibition of protein kinase C in a substratum-dependent manner显示文摘 | Zhou Y Dziak E Opas M | 1993 | J Cell Physiol1993，155，1： | 1 |
| 12 | Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle ceils显示文摘 | Opas M Dziak E Fliegel L | 1991 | Cell Physiol1991，149，1： | 1 |
| 13 | Virtual reality enhanced volumetric cellular visualization显示文摘 | Guan Y Q Cai Y Y Opas M | 2005 | Current Issues on Multidisciplinary Microscopy Research and Education2005，，： | 1 |
| 14 | A modified Hough transform for line detection and its performance显示文摘 | OPAS CHUTATAPE LINFENG GUO | 1999 | Pattern Recognition1999，，32： | 1 |
| 15 | Requirement of a 5-1ipoxygenaseactivating protein for leukotriene synthesis 显示文摘 | Dixon RA Diem RE Opas E | 1990 | Nature1990，343，6255： | 1 |
| 16 | Calreticulin,Ca^2+ -binding chanperon of the endoplasmic reticulum显示文摘 | SZPERLI M OPAS M | 2005 | Poatepy Biochem2005，51，4： | 1 |
| 17 | Calreticulin,a Ca^2+ -binding chaperone of the endoplasmic reticulum显示文摘 | GELEBART P OPAS M MICHALAK M | 2005 | Int J Biochem Cell Biol2005，37，2： | 1 |
| 18 | Calreticulin, a Ca^2+- binding chaperone of the endoplasmic retieulum显示文摘 | Gelebar TP Opas M Michala KM | 2005 | Int J Bioehm Cell Biol2005，37，： | 1 |
| 19 | Calreticulin, a Ca 2+ -binding chaperone of the endoplasmic reticulum显示文摘 | Pascal Gelebart Michal Opas Marek Michalak | 2004 | International Journal of Biochemistry and Cell Biology2004，，2： | 1 |
| 20 | The ins and outs of calreticulin:from the ER lumen to the extracellular space显示文摘 | Johnson S Michalak M Opas M | 2001 | Trend Cell Biol2001，11，： | 1 |
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