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| 1 | Multimodality treatment strategies have changed prognosis of peritoneal metastases显示文摘For a long time, treatment of peritoneal metastases(PM) was mostly palliative and thus, this status was link with 'terminal status/despair'. The current multimodal treatment strategy, consisting of cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC), has been strenuously achieved over time, but seems to be the best treatment option for PM patients. As we reviewed the literature data, we could emphasize some milestones and also, controversies in the history of proposed multimodal treatment and thus, outline the philosophy of this approach, which seems to be an unusual one indeed. Initially marked by nihilism and fear, but benefiting from a remarkable joint effort of human and material resources(multi-center and-institutional research), over a period of 30 years, CRS and HIPEC found their place in the treatment of PM. The next 4 years were dedicated to the refinement of the multimodal treatment, by launching research pathways. In selected patients, with requires training, it demonstrated a significant survival results(similar to the Hepatic Metastases treatment), with acceptable risks and costs. The main debates regarding CRS and HIPEC treatment were based on the oncologists' perspective and the small number of randomized clinical trials. It is important to statement the PM patient has the right to be informed of the existence of CRS and HIPEC, as a real treatment resource, the decision being made by multidisciplinary teams. | corneliu lungoci aurel ion mironiuc valentin muntean traian oniu hubert leebmann max mayr pompiliu piso | 2016 | World Journal of Gastrointestinal Oncology2016，8，1： | 2 |
| 2 | Circulatory and re spiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 3 | Krukenberg tumors of gastric o-rigin versus Krukenberg tumors of colorectal origin显示文摘 | Man M M Cazacu T Oniu | | 0，，： | 1 |
| 4 | Fewer adhesions induced by laparoscopic surgery 显示文摘 | Gutt CN Oniu T Schemmer P | 2004 | Surg Endosc2004，18，6： | 1 |
| 5 | Staging laparoscopy in digestive cancers显示文摘 | Muntean V Oniu T Lungoci C | 2009 | J Gastrointestin Liver Dis2009，18，4： | 1 |
| 6 | Circul- atory and respiratory complications of carbon dioxide insuffiation 显示文摘 | Gutt C N Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 7 | Circulatory and respiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 8 | Staging laparoscopy in digestive cancers 显示文摘 | Muntean V Oniu T Lungoei C | 2009 | J Gaslrointestin Liver Dis2009，18，4： | 1 |
| 9 | Circulatory and respiratory complications of carbon dioxide insuftlation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，2，1： | 1 |
| 10 | The influence of Isorel on the ad-vanced colorectal cancer显示文摘 | CAZACU M ONIU T LUNGOCI C | 2003 | Cancer Biother Radio2003，18，1： | 1 |
| 11 | Cir- culatory and respiratory complications of carbondioxide insufflations 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 12 | Circulatory and respirato-ry complications of carbon dioxide insufflation 显示文摘 | Gutt C N Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 13 | Circulatory and respiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 14 | Circulatory and respiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 15 | Circulatory and respiratory complications of carbon dioxide insufflation 显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 16 | Fewer adhesions induced by laparo- scopic surgery显示文摘 | Gutt C N Oniu T Schemmer P | 2004 | Surg Endo sc2004，18，6： | 1 |
| 17 | Robot-assisted abdominal surgery显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | British Journal of Surgery2004，91，11： | 1 |
| 18 | Sound generation in a mixing layer显示文摘 | COI~ONIUS T LELE S MOIN P | 1997 | Journal of Fluid Mechanics1997，330，： | 1 |
| 19 | Circulatory and respira- tory complications of carbon dioxide insufflation 显示文摘 | Gutt C N Oniu T Mehrabi A | 2004 | Dig Surg2004，21，2： | 1 |
| 20 | Robot-assisted abdominal surgery显示文摘 | Gutt CN Oniu T Mehrabi A | 2004 | Br J Surg2004，91，11： | 1 |
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