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| 1 | Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis显示文摘The liver is an important site for iron and lipid metabolism and the main site for the interactions between these two metabolic pathways. Although conflicting results have been obtained, most studies support the hypothesis that iron plays a role in hepatic lipogenesis. Iron is an integral part of some enzymes and transporters involved in lipid metabolism and, as such, may exert a direct effect on hepatic lipid load, intrahepatic metabolic pathways and hepatic lipid secretion. On the other hand, iron in its ferrous form may indirectly affect lipid metabolism through its ability to induce oxidative stress and inflammation, a hypothesis which is currently the focus of much research in the field of nonalcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH). The present review will first discuss how iron might directly interact with the metabolism of hepatic lipids and then consider a new perspective on the way in which iron may have a role in the two hit hypothesis for the progression of NAFLD via ferroportinand the iron regulatory molecule hepcidin. The review concludes that iron has important interactions with lipid metabolism in the liver that can impact on the development of NAFLD/NASH. More defined studies are required to improve our understanding of these effects. | Umbreen Ahmed Patricia S Latham Phillip S Oates | 2012 | World Journal of Gastroenterology2012，18，34： | 20 |
| 2 | 无精症男性的病因分析显示文摘对一个无精症病例来说,透彻的病史分析和详细周全的体检常常能得出一个明确的或推测性的诊断结果。系统、逻辑的思考过程对最后得出结果是非常重要的。辅助性的实验室检查,如,激素检查或遗传学分析,对于病因学研究(不管是遗传性的还是后天获得性的)通常是互补的或/和可以有额外的收获,以得到一个准确的病因结论。有了这个信息才可以为病人制定一个治疗方案。所以一个明确的有针对性的实验室检查方案远比盲目、随意的诊断更令人满意、更省钱。 | Robert Oates | 2012 | Asian Journal of Andrology2012，14，1： | 9 |
| 3 | Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility显示文摘胃肠道被经历包含两极分裂,区别和细胞死亡的经常的更新的一张单层上皮衬里。另外,上皮的衬里分开由保护上皮免受被突破的伤害的防御机制从内部周围的无菌的环境发生在肠的腔的消化和吸收的敌对过程。对这些防御过程中央是合成他我和它的分解代谢由他我氧合酶(惊讶) 。饮食他我也是为被收起的身体的铁的重要来源由 enterocyte 未经触动。这评论在肠道在 heme/HO 的多样的性质上描述最近的文学。在房间 cycle/apoptosis, xenobiotics 的 detoxification,氧化压力,发炎,结肠癌的发展, heme 铁吸收和肠的活动性的规定的 heme/HO 的角色明确地被检验。 | Phillip S Oates Adrian R West | 2006 | World Journal of Gastroenterology2006，12，27： | 8 |
| 4 | Mechanisms of heme iron absorption:Current questions and controversies显示文摘Iron is a critical micronutrient, and iron derived from heme contributes a large proportion of the total iron absorbed in a typical Western diet. Heme iron is absorbed by different mechanisms than non-heme iron, but despite considerable study over many years these mechanisms remain poorly understood. This review provides an overview of the importance of heme iron in the diet and discusses the two prevailing hypotheses of heme absorption; namely receptor mediated endocytosis of heme, and direct transport into the intestinal enterocyte by recently discovered heme transporters. A specific emphasis is placed on the questions surrounding the site of heme catabolism and the identity of the enzyme that performs this task. Additionally, we present the hypothesis that a non-heme iron transport protein may be required for heme iron absorption and discuss the experiences of our laboratory in examining this hypothesis. | Adrian R West Phillip S Oates | 2008 | World Journal of Gastroenterology2008，14，26： | 5 |
| 5 | 块根与块茎淀粉显示文摘本文是一篇关于块根与块茎淀粉的综述,从历史与市场潜力的角度,论述了此类淀粉潜在的资源,从产率、提取淀粉的纯度,原材料供应在市场以及淀粉加工的探讨,并着重论述了不同淀粉的功能性质和特性。 | Oates,CG 蒋高松 | 1997 | 淀粉与淀粉糖1997，，1： | 4 |
| 6 | Toward A Second-Generation Theory of Fiscal Federalism显示文摘 | Wallace E. Oates | | International Tax and Public Finance0，，： | 2 |
| 7 | Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury显示文摘 | Ramasamy R Oates P J Schaefer S | 1997 | Diabetes1997，46，2： | 1 |
| 8 | Mutations in PAXI may be associated with Klippel - Feil syndrome显示文摘 | MeGaughran Ji Oates A Donnai D | 2003 | Eur J Hum Genet2003，11，： | 1 |
| 9 | Solar disinfection(SODIS)' simulation of solar radiation for global assessment and application for point-of-use water treatment in Haiti显示文摘 | Peter M Oates Peter Shanahan Martin F Polz | 2003 | Water Research2003，37，1： | 1 |
| 10 | The role of osteopontin in tuworigenesis and metastasis 显示文摘 | Oates AJ Barraclough R Rudland PS | 1997 | Invasion Metastasis1997，17，： | 1 |
| 11 | ,An Essay on Fiscal Federalism 显示文摘 | Oates W | 1999 | Journal of Eco- nomic Literature1999，，3： | 1 |
| 12 | Suboptimal Inhibition of Platelet Cyclooxygenase-1 by Aspirin in Metabolic Syndrome显示文摘 | James P. Smith Elias V. Haddad Mary B. Taylor Denise Oram Dana Blakemore Qingxia Chen Olivier Boutaud John A. Oates | 2012 | Hypertension2012，，3： | 1 |
| 13 | The relationship between dose of vitamin E and suppression of oxidative stress in humans显示文摘 | L Jackson Ⅱ Roberts John A Oates MacRae F Linton | | 0，，10： | 1 |
| 14 | Designing glucokinasc activators with reduced hypoglycemia risk: discovery of N,N-dimethyl- 5-(2-methyt-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy) pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus显示文摘 | Pfefferkorn J A Guzman-Perez A Oates P L | 2011 | Med Chem Comm2011，2，9： | 1 |
| 15 | The effects of property taxes and local public spending on property values: An empirical study of tax capitalization and the A reply and yet further results 显示文摘 | Oates W E | 1973 | Journal of Political Economy1973，81，4： | 1 |
| 16 | Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD显示文摘 | Di Stefano A Caramori G Oates T | 2002 | Eur Respir J2002，20，3： | 1 |
| 17 | Fiscal Decentralization and Economic Development显示文摘 | Oates W E | 1993 | National Tax Journal1993，，： | 1 |
| 18 | The Effects of Property Taxes and Local Public Spending on Property Values: An Empirical Study of Tax Capitalization and the Tiebout Hypothesis显示文摘 | Wallace E Oates | 1969 | The Journal of Political Economy1969，，6： | 1 |
| 19 | Mitogenic effects of growth factors on human periodontal ligament cells in vitor显示文摘 | Rouse CA Cochran DL | 1993 | J Periodontal1993，64，2： | 1 |
| 20 | A modified version of the Bayley scales of infant development - Ⅱ for cognitive matching of infants with and without Down syndrome 显示文摘 | Moore DG Goodwin JE Oates JM | 2008 | J Intellect Disabil Res2008，52，6： | 1 |
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