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| 1 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 3 |
| 2 | Attributes of cancer patients admitted to the emergency department in one year显示文摘BACKGROUND: Cancer patients frequently visit the emergency department(ED) with various symptoms of cancer. The purpose of this study was to determine the clinical characteristics and 1-year survival rate of cancer patients in the ED of a university hospital.METHODS: We conducted a retrospective review of 408 cancer patients who visited the ED between January 2011 and December 2011. Patient information on demographics, chief complaints, fi ndings, and survival was gathered from the hospital registry and corresponding health administration.RESULTS: The study included 240(58.8%) males and 168(41.2%) females with a median age of 57.9 years(range 19–87). Regarding cancer staging, 266 patients(65.3%) had metastatic disease and 142(34.7%) had local and loco-regional disease. The hospitalization rate was 59.6%. The most common symptoms were shortness of breath(23.2%), pain(17.8%), fever(14.2%), and nausea/vomiting(14.4%). The most common cancer sites were the lung(32.5%), gastrointestinal system(25.4%), and breast(9.3%). The initial evaluation determined progressive disease(42.4%), chemotherapy effects(20.7%), infections(17.2%), radiotherapy effects(4.7%), extravasation(1.8%), anemia(1.4%), and unknown(11.3%). During follow up, 191(46.8%) patients died after admission to the ED. The 1-year overall survival of all patients was 7.3 months.CONCLUSIONS: Symptom management in cancer patients is a complex multifaceted concern for the emergency physician. Because of the increasing prevalence of cancer patients, emergency physicians should develop consensus algorithms in collaboration with the relevant disciplines to manage the commonly encountered problems. | Muallaoglu Sadik Karagün Ozlem Mertsoylu Huseyin Besen AliAyberk Sezer Ahmet Ozyilkan Ozgur | 2014 | World Journal of Emergency Medicine2014，5，2： | 3 |
| 3 | Langenbecks Arch Surg显示文摘 | Ozlem N Ozdogan M Gurer A Gomceli I Aydin R | | 0，，03： | 1 |
| 4 | A Comparison of Nonabsorbable Polymeric Clips and Endoloop Ligatures for the Closure of the Appendieular Stump in Laparoscopic Appendectomy: A Prospective, Randomized Study 显示文摘 | Colak E Kement M Ozlem N | 2013 | Surg Laparosc Endosc Percutan Tech2013，23，3： | 1 |
| 5 | Uncommon content in groin hernia sac显示文摘 | Gurer A Ozdogan M Ozlem N Yildirim A Kulacoglu H Aydin R | 2006 | Hernia2006，10，2： | 1 |
| 6 | Graft copolymerization of butyl acrylate and 2 - ethyl hexyl acrylate from labile chlorines of poly(vinyl chloride) by atom transfer radical polymerization显示文摘 | N Bicak M Ozlem | 2003 | J Polym Sci Part A: Polym Chem2003，41，： | 1 |
| 7 | A rare inguinal mass: Round ligament leiomyoma 显示文摘 | COLAK E OZLEM N KESMER S | 2013 | Int J Surg Case Rep2013，4，7： | 1 |
| 8 | Achievement Orientations from Subjective Histories of Success:Promotion Price versus Prevention Pride 显示文摘 | Higgins E T Roney C Ronald S Friedman Robert E Harlow Lorrain Chen Idson Ozlem N Ayduk Amy Taylor | 2001 | European Journal of Social Psychol- ogy2001，31，7： | 1 |
| 9 | 查看详情显示文摘 | Bicak N Ozlem M | | 0，，： | 1 |
| 10 | A novel material in seton treatment of fistula-in-ano 显示文摘 | Gurer A Ozlem N Gokakin A K | 2007 | American Journal of Surgery2007，193，6： | 1 |
| 11 | Role of natural products and intestinal flora on type 2 diabetes mellitus treatment显示文摘Diabetes mellitus(DM)is a complicated,globally expanding disease that is influenced by hereditary and environmental variables.Changes in modern society’s food choices,physical inactivity,and obesity are significant factors in the development of type 2 DM(T2DM).The association between changes in intestinal flora and numerous disorders,including obesity,diabetes,and cardiovascular diseases,has been studied in recent years.The purpose of this review is to analyze the mechanisms underlying the alteration of the diabetic patients’intestinal flora,as well as their therapeutic choices.Also included is a summary of the antidiabetic benefits of natural compounds demonstrated by studies.The short-chain fatty acids theory,the bile acid theory,and the endotoxin theory are all potential methods by which intestinal flora contributes to the establishment and progression of T2DM.Due to an intestinal flora imbalance,abnormalities in shortchain fatty acids and secondary bile acids have been found in diabetic patients.Additionally,metabolic endotoxemia with altering flora induces a systemic inflammatory response by stimulating the immune system via bacterial translocation.The agenda for diabetes treatment includes the use of short-chain fatty acids,probiotics,prebiotics in the diet,fecal bacteria transplantation,and antibiotics.Animal studies have proven the antidiabetic benefits of numerous bioactive substances,including Flavonoids,Alkaloids,Saponin,and Allicin.However,further research is required to contribute to the treatment of diabetes. | Ozlem Celik Aydin Sonay Aydın Sureyya Barun | 2023 | World Journal of Clinical Cases2023，11，1： | 1 |
| 12 | Uncommon content in groin hernia sac显示文摘 | Gurer A Ozdogan M Ozlem N | 2006 | Henia2006，10，2： | 1 |
| 13 | Mutlu TA comparison of nona- bsorbable polymeric clips and endoloop ligatures for the closure of the appendicular stump in laparoscopic appendectomy: a pros- pective,randomized study显示文摘 | Colak E Kement M Ozlem N | 2013 | Surg Laparosc Endosc Percutan Tech2013，23，3： | 1 |
| 14 | Mediastinal intraoperative radioisotope sentinel lymph node mapping in non- small-cell lung cancer 显示文摘 | Atinkaya C Ozlem Ktictik N Koparal H | 2005 | Nucl Med Commun2005，26，8： | 1 |
| 15 | Graft copolymerization of butyl acrylate and 2-ethyl hexyl acrylate from labile chlorines of poly(vinyl chloride)by atom transfer radical polymerization显示文摘 | Bicak N Ozlem M | 2003 | Journal of Polymer Science:Polymer Chemistry2003，41，21： | 1 |
| 16 | Analysis and network representation of hotspots in protein interfaces using minimum cut trees显示文摘 | Tuncbag N Sibel Salman F Ozlem Keskin | 2010 | Proteins2010，78，10： | 1 |
| 17 | A novel material in seton treatment of fistula-in-ano显示文摘 | GURER A OZLEM N GOKAKIN AK | 2007 | Am J Surg2007，193，6： | 1 |
| 18 | A novel material in seton treatment of fistula - in - ano 显示文摘 | GURER A OZLEM N GOKAKIN AK | 2007 | Am J Surg2007，193，6： | 1 |
| 19 | A novel material in seton treatment of fistulainano 显示文摘 | Gurer A Ozlem N Gokakin AK | 2007 | Am J Surg2007，193，79： | 1 |
| 20 | Mediastinal intraoperative radioisotope sentinel lymph node mapping in non-small-cell lung cancer 显示文摘 | Atinkaya C Ozlem Kucuk N Koparal H | 2005 | Nucl Med Commun2005，26，8： | 1 |
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