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1标准·方案·指南——2014年美国癌症学会最新宫颈癌筛查指南及筛查中存在的问题显示文摘美国癌症学会(ACS)每年都会发布有关癌症早期检测、癌症筛查率数据与趋势报告及相关问题的指南,并会持续关注可能需要在癌症筛查指南中做出相应改变与更新的医学科学文献中出现的新证据以及需要传达给临床工作者与公众的筛查相关信息。在制定新指南的过程中,ACS至少每5年对指南更新1次,如有重要新证据出现,则更新间隔时间会更短。本期就2014年ACS关于宫颈癌筛查的最新指南报道如下。Robert A Smith Deana Manassaram-Baptiste Durado Brooks Vilma Cokkinides Mary Doroshenk Debbie Saslow Richard C Wender Otis W Brawley 王静 2014中国全科医学2014,17,27:16
2An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing显示文摘Prolonged,intense inflammation and excessive oxidative stress hinder diabetic wounds from healing normally,leading to disorders downstream including the postponement of re-epithelialization and extracellular matrix(ECM)formation.Herein,we report a hyaluronic acid(HA)and chitosan based hydrogel(OHA-CMC)with inherent antibacterial and hemostatic activities fabricated via Schiff base reaction.By encapsulating nanotechnologically-modified curcumin(CNP)and epidermal growth factor(EGF)into the hydrogel,OHA-CMC/CNP/EGF exhibited extraordinary antioxidant,anti-inflammatory,and migration-promoting effects in vitro.Meanwhile,OHA-CMC/CNP/EGF presented on-demand drug release in synchrony with the phases of the wound healing process.Specifically,curcumin was rapidly and constantly released to alleviate inflammation and oxidative stress in the early phase of wound healing,while a more gradual and sustained release of EGF supported late proliferation and ECM remodeling.In a diabetic full-thickness skin defect model,OHA-CMC/CNP/EGF dramatically improved wound healing with ideal re-epithelialization,granulation tissue formation,and skin appendage regeneration,highlighting the enormous therapeutic potential this biomaterial holds as a diabetic wound dressing.Bin Hu Mingzhu Gao Kofi Oti Boakye-Yiadom William Ho Wei Yu Xiaoyang Xu Xue-Qing Zhang 2021Bioactive Materials2021,6,12:4
3分子机器并非幻想显示文摘Otis Port 王乃粒 2000世界科学2000,22,1:3
4ABH and Lewis antigen distributions in blood,saliva and gastric mucosa and H pylori infection in gastric ulcer patients显示文摘瞄准:调查 ABH 和路易斯抗原在红血球,口水和胃的上皮的表示,以及在 H pylori 和胃的上皮的损害的存在之间的协会。方法:在 H 感染 pylori 的胃溃疡病人的红血球,口水和胃粘膜的 ABH 和路易斯血型抗原的分发被分析。有胃溃疡的 42 个病人被学习,并且五十个健康个人被用作控制组。血型抗原被直接红血球凝聚, dot-ELISA 和免疫决定在红血球,口水和胃粘膜标本的组织化学的方法分别地。为 H pylori 感染的诊断被常规光显微镜学和 ELISA 执行。结果:IgG H pylori specific 抗体的更高的 seroprevalence 与控制组(60%) 相比在胃溃疡病人(90%) 被观察。我们在 H 感染 pylori 的病人观察了显型 O, A2 和路易斯 b 的重要增加。这些抗原的表示在溃疡性的损害和肠的组织变形的区域有进步改变。结论:ABH 和路易斯血型抗原是为在胃的上皮的细胞的改变的好指示物。LuisaCaricioMartins TerezaCristinadeOliveiraCorvelo Henrique Takeshi Oti RosanedoSocorroPompeuLoiola DéliaCristinaFigueiraAguiar KatarineAnt niadosSantosBarile RenataKellyCostadoAmaral HivanaPatriciaMeloBarbosa AmandaAlvesFecury JuciclaytonTavaresdeSouza 2006World Journal of Gastroenterology2006,12,7:3
5癌症筛查之未来显示文摘1引言癌症已成为美国的第二大致死病因,52%的人死于肺癌、支气管癌、女性乳腺癌、宫颈癌、结直肠癌、口腔及咽喉癌、前列腺癌和皮肤癌(黑色素瘤)。19世纪30年代,包括宫颈癌在内的子宫癌,位居美国女性癌症死亡第一位。50年代,随着巴氏涂片技术(Pap test)的应用,可以在细胞水平检测宫颈的变化,宫颈癌死亡率显著降低,这是第一个癌症筛查检测技术。此后,已有多种影像学检查(例如乳腺癌钼靶X线、内窥镜检查和计算机体层扫描)和实验室检测方法(粪便隐血试验)用于癌症筛检。Cheryll C.Thomas Thomas B.Richards Marcus Plescia Faye L.Wong Rachel Ballard Theodore R.Levin Bruce N.Calonge Otis W.Brawley John Iskander 徐海燕(翻译) 陆仁敏(审校) 蔡颖(审校) 2017上海预防医学2017,29,3:2
6A method for spatial–temporal forecasting with an application to real estate prices显示文摘R.Kelley Pace Ronald Barry Otis W. Gilley C.F. Sirmans 2000International Journal of Forecasting2000,,2:2
7Cancer screening in the United States, 2014: A review of current American Cancer Society guidelines and current issues in cancer screening显示文摘Robert A. Smith Deana Manassaram-Baptiste Durado Brooks Vilma Cokkinides Mary Doroshenk Debbie Saslow Richard C. Wender Otis W. Brawley 2014CA A Cancer Journal for Clinicians2014,,:2
8The unsatisfactory nargin in breast cancer surgery 显示文摘Luu HH Otis CN Reed WP Jr 1999Am J Surg1999,178,5:2
9Calcineurin activation influences muscle phenotype in a muscle-specific fashion显示文摘Talmadge RJ Otis JS RiUler MR 2004BMC Cell Biol2004,5,:1
10Design of ultra-low power biopotential amplifiers for biosignaI acquisition applications显示文摘ZHANG Fan HOLLEMAN J OTIS B P 2012IEEE Transactions on Biomedical Circuits and Systems2012,,6:1
11The impact of eliminating socioeconomic and racial disparities on premature cancer deaths 显示文摘Rebecca S Elizabeth W Otis B 2011CA Cancer J Clin2011,61,:1
12Revalence, awareness, treatment and control of hypertension among slum dwellers in Nairobi, Kenya 显示文摘vande Vijver SJ Oti SO Agyemang C 2013J Hypertens2013,31,5:1
13Cannabinoids in pancreatic cancer: correlation with survival and pain显示文摘MICHALSKI C W OTI F E ERKAN M 2008Inte J Can2008,122,4:1
14An experiment thermal time-constant correlation for hydraulic accumulators显示文摘Pourmovahed A Otis D R 1990Journal of Dynamic Systems Measurement and Control1990,1990,112:1
15Effects of stress on susceptibility of native channel catfish in immersion challenge with Edwardsiella ictalui显示文摘WISE D J SCHWEDLER T E OTIS D L 1993Aquat Anim Health1993,,5:1
16Distribution of carbon,nitrogen and phosphorus in water-stable aggregates of an organic waste amended Ultisol in southern Nigeria显示文摘Adesodun J.K Mbagwu J.S.C Oti N 0,,:1
17Pain in muhiple sclerosis: a biopsychosocial perspective 显示文摘Kerns R D Kassirer M Otis J 2002J Rehabil Res Dev2002,39,:1
18Calibrating Recruitment Estimates for Mourning Doves From Harvest Age Ratios显示文摘Miller David A Otis David L 2010Journal of Wildlife Management2010,,:1
19An algorithm for computing nonflow gas processes in gas springs and hydropneumatic Accumulator显示文摘Otis D R Pourmovahed A 1985Journal of Dynamic Systems Measurement and Control1985,1985,107:1
20Prevalence of chronic pain, posttrau- rnatic stress disorder, and persistent post concussive symptoms in OIF/OEF veterans:Polytranma clinical triad显示文摘Lew HL Otis J D Tun C 2009J Rehabil Res Dev2009,46,6:1
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