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| 1 | 脉搏波传导速度预测青年人血压进展与高血压发生显示文摘该研究旨在评估脉搏波传导速度(pulse wave velocity,PWV)是否能够预测青年人血压进展及高血压的发生,并探讨除传统心血管病危险因素外,PWV是否可改善高血压发生的风险预测。Koivistoinen等于2007年及2011年分别测量1449例芬兰成人(年龄30~45岁)的收缩压及舒张压水平。此外,于2007年还测定了其PWV及其他心血管病危险因素。 | Koivistoinen T Lyytik?inen LP Aatola H Luukkaala T Juonala M Viikari J Lehtim?ki T Raitakari OT K?h?nen M Hutri-K?h?nen N 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，1： | 12 |
| 2 | 儿童期肥胖、成年期肥胖和心血管风险因子显示文摘过去30年,儿童超重或肥胖的发生率明显增加[1]。儿童期肥胖是死亡率增加的预测因子,这主要是由于儿童期肥胖可导致心血管疾病发生率增加。相关的预测研究提示"肥胖流行症"可能改变目前心血管疾病死亡率下降的趋势,使现今儿童的寿命缩短。 | Juonala M Magnussen CG Berenson GS Venn A Burns TL Sabin MA Srinivasan SR Daniels SR Davis PH Chen W Sun C Cheung M Viikari JS Dwyer T Raitakari OT 叶鹏 | 2012 | 中华高血压杂志2012，20，1： | 6 |
| 3 | Helicobacter pylori and EBV in gastric carcinomas:Methylation status and microsatellite instability显示文摘AIM:To verify the methylation status of CDH1, DAPK, COX2, hMLH1 and CDKN2A genes and to evaluate their association with Helicobacter pylori (H. pylori)-cagA+ and Epstein Barr virus (EBV) infections in gastric adenocarcinomas.METHODS: Methylation-specific PCR (MSP) assay was performed in 89 primary gastric carcinomas (intestinal and diffuse types). Microsatellite instability (MSI) analysis was performed using the BAT26 primer set and PCR products were analyzed with the ABI PRISM 3100 Genetic Analyzer using Genescan 3.7 software (Applied Biosystems). Detection of H. pylori and genotyping were performed by PCR, using specifi c primers for ureaseC and cagA genes. The presence of EBV was assessed by in situ hybridization. Statistical analyses were performed using the χ2 or Fisher's exact test.RESULTS: The most frequent hypermethylated gene was COX-2 (63.5%) followed by DAPK (55.7%), CDH1 (51%), CDKN2A (36%) and hMLH1 (30.3%). Intestinal and diffuse adenocarcinomas showed different methylation profiles and there was an association between methylation of E-CDH1 and H. pylori-cagA+ in the intestinal adenocarcinoma type. MSI was correlated with hMLH1 methylation. There was an inverse correlation between DAPK hypermethylation and MSI.CONCLUSION: We found a strong association between CDH1 methylation and H. pylori-cagA+ in intestinal-type gastric cancer, association of MSI and better prognosis and an heterogeneous COX-2 overexpression. | Adriana Camargo Ferrasi Nídia Alice Pinheiro Silvia Helena Barem Rabenhorst Otávia Luisa Caballero Maria Aparecida Marchesan Rodrigues Fabrício de Carvalho Celso Vieira de Souza Leite Marcia Valéria Pitombeira Ferreira Marcos Aurélio Pessoa Barros Maria Inês de Moura Campos Pardini | 2010 | World Journal of Gastroenterology2010，16，3： | 6 |
| 4 | Improvement in corrosion resistance of magnesium coating with cerium treatment显示文摘Corrosion protection afforded by a magnesium coating treated in cerium salt solution on steel substrate was investigated using open circuit potential, polarization curves, and electrochemical impedance spectroscopy (EIS) in 0.005 M sodium chloride solution (NaCl). The morphology of the surface was characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD). The cerium treated coating was obtained by immersion in CeCl3 solution. The results showed that the corrosion resistance of the treated magnesium coating was improved. The corrosion potential of the treated coating was found to be nobler than that of the untreated magnesium coating and the corrosion current decreased significantly. Impedance results showed that the cerium treatment increased corrosion protection. The improvement of anti-corrosion properties was attributed to the formation of cerium oxides and hydroxides that gave rise to a physical barrier effect. | Samia Ben Hassen Latifa Bousselmi Patrice Berot El Mustafa Rezrazi Ezzeddine Triki | 2009 | Rare Metals2009，28，3： | 5 |
| 5 | Understanding plant drought resistance in a Mediterranean coastal sand dune ecosystem:differences between native and exotic invasive species显示文摘Aims Mediterranean coastal dunes are habitats of great conservation interest,with a distinctive and rich flora.In the last century,Acacia spp.,native from Australia,have been introduced in Portugal,with the objective of stabilizing sand dunes,and since have become dominant in numerous sand dune habitats.This invasion process led to the reduction of native plant species richness,changed soil characteristics and modified habitat’s microclimatic char-acteristics.The aim of this research was to typify and compare,in Mediterranean sand dune ecosystems,the ecophysiological responses to drought of Helichrysum italicum and Corema album,two native species,and Acacia longifolia,an exotic invasive spe-cies.We addressed the following specific objectives:(i)to com-pare water relations and water use efficiencies,(ii)to evaluate water stress,(iii)to assess water use strategies and water sources used by plants and(iv)to evaluate the morphological adaptations at leaf and phyllode level.Methods In order to obtain an integrative view of ecophysiological patterns,water relations and performance measuring methods have been applied:predawn(ψPD)and midday(ψMD)water potential,chloro-phyll a fluorescence,oxygen isotopic composition of xylem,rain and groundwater(δ18O)and leaf carbon isotopic discrimination(Δ13C).The leaf characteristics of the three species,as well as the histochemistry of non-glandular trichome cell walls,were also studied to identify morpho-traits related to drought resistance.Important Findings The results support our initial hypothesis:although A.longifolia clearly possesses a degree of resistance to water stress,such ability is provided by a different water strategy,when compared to native species.Natives relied on morphological adaptations to restrict water loss,whereas the invasive species adjusted the water uptake as a way to balance their limited ability of restricting water loss.We corroborate that woody native species(i)have a conservative water-saving strategy and minor seasonal variations relative to invasive species,(ii)use enriched water sources during drought periods,indicating different water sources and root systems com-paring with invasive species and(iii)present drought leaf morpho-functional adaptations related with limiting water loss.Comparing the physiological performance of invasive and native species can offer causal explanations for the relative success of alien plant invasions on sand dunes ecosystems. | Cristina Antunes Ana Júlia Pereira Patrícia Fernandes Margarida Ramos Lia Ascensão Otília Correia Cristina Máguas | 2018 | Journal of Plant Ecology2018，11，1： | 4 |
| 6 | 儿童和成人血压升高对成人动脉僵硬度的影响——芬兰年轻人心血管风险研究显示文摘用脉搏波传导速度(pulse wave velocity,PWV)评估的动脉僵硬度是心血管病的一项替代指标,是心血管事件和全因死亡率的独立预测因素。弹性动脉的僵硬度随年龄增大而增加,主要是由左心室产生的搏动性机械应力造成动脉壁弹性蛋白层的疲劳和断裂所致。高收缩压增加心脏负荷和动脉应力,因此加速心血管退化和动脉粥样硬化。研究已证明儿童期血压是成年期PWV的独立预测因素,且血压,尤其是血压升高,可从儿童期追踪到成年期。 | Aatola H Koivistoinen T Tuominen H Juonala M Lehtimaki T Viikari JSA Raitakari OT Kahonen M Hutri-Kahonen N 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 4 |
| 7 | Liver retransplantation: indications and outcomes显示文摘BACKGROUND: Liver transplantation is a life-saving the- rapeutic modality for patients with end-stage liver diseases. After liver transplantation, however, more than 10% pa- tients may lose the grafts caused by a variety of reasons. This review covers the most frequent indications for liver retransplantation as well as the results and specific problems with each indication. DATA RESOURCES: Searching MEDLINE (1997-2003) for articles on liver retransplantation. RESULTS: The most frequent indications of liver retrans- plantation are primary non-function, hepatic artery throm- bosis, graft rejection and recurrent diseases. The results af- ter liver retransplantation remain inferior to those after first transplantation. CONCLUSION: Liver retransplantation, which is the only means of prolonging survival in those patients whose initial graft has failed, makes an important contribution to overall survival. | Zi-Fa Wang and Chang Liu Pittsburgh, USA Department ot Surgery, University of Pittsburgh Me- dical Center, Pittsburgh, PA 15213, USA Division of Hepa- tobiliary Surgery . First Hospital, Xi’ an Jiaotong University , Xi’ an 710061, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，2： | 4 |
| 8 | 激光诱导荧光技术测量大气OH自由基的研究进展显示文摘大气氢氧自由基(OH)是对流层大气中最重要的氧化剂,对酸雨、平流层臭氧的损耗等有重要影响。激光诱导荧光技术是目前测定大气OH自由基中使用最多的测量方法。文章总结了20多年来国内外的研究成果,论述了激光诱导荧光技术用于测定大气OH自由基的基本原理和研究进展,讨论了测量中不确定因素及其对策,并着重介绍了目前最常用的基于气体扩张的低压荧光(FAGE)技术。 | 任信荣 Matthias Otting 田洪海 | 1999 | 上海环境科学1999，18，12： | 3 |
| 9 | OH自由基绝对标定系统的建立和研究显示文摘利用H2 O在 1 85nm紫外光照射下产生定量OH自由基 ,用低压扩散激光诱导荧光技术建立了OH自由基标定系统 .在实验条件下 ,体系产生OH自由基的浓度范围为 3× 1 0 7— 2× 1 0 9个·cm- 3,得到归一化荧光信号 (S)与OH自由基浓度的定量关系为S =6 0 4× 1 0 - 9[OH]- 0 0 4 0 7(R2 =0 987) ,并研究和讨论了饱和效应以及体系中可能存在的干扰 . | 任信荣 Matthias Otting 邵可声 唐孝炎 | 2000 | 环境科学学报2000，20，6： | 3 |
| 10 | 使用外源性蛋白酶提高免疫力显示文摘在动物饲料中使用蛋白酶通常是为了降低饲料成本。然而,通过最大限度地提高蛋白饲料的消化率,动物生产者可以降低日粮的粗蛋白水平,使用低成本的蛋白饲料,且不会影响动物的健康和生产性能。 | José Otávio B.Sorbara 杨革玲(译) 王晶晶(校) 靳文广(制表) | 2017 | 国外畜牧学(猪与禽)2017，0，5： | 3 |
| 11 | 支撑国土资源管理 服务经济社会发展 促进地籍信息化建设再上新台阶显示文摘地籍工作是国土资源管理的基础,是一项打基础、利长远的工作。从原国家土地管理局到建部以来,地籍信息化建设一直未曾停止过,取得了重要进展和明显成效。1多年来特别是"十一五"期间,我国地籍信息化建设成效显著我国地籍信息化建设呈三个阶段性特点:一是起步早;二是发展快;三是成效显著。 | Department of Cadastral Management Division,ministey ot Lane and Resources | 2012 | 国土资源信息化2012，，2： | 2 |
| 12 | Structural phase relations in perovskite-structured BiFeO_(3)-based multiferroic compounds显示文摘In this review,the state of the art in understanding the structural phase relations in perovskite-structured BiFeO_(3)-based polycrystalline solid solutions is presented and discussed.Issues about the close relation between the structural phase and overall physical properties of the reviewed systems are pointed out and discussed.It is shown that,by adjusting the structural symmetric arrangement,the ferroelectric and magnetic properties of BiFeO_(3)-based polycrystalline solid solutions can be tuned to find specific multifunctional applications.However,an intrinsic mechanism linking structural arrangement and physical properties cannot be identified,revealing that this subject still deserves further discussion and investigation. | Valdirlei Fernandes FREITAS Gustavo Sanguino DIAS Otávio Algusto PROTZEK Diogo Zampieri MONTANHER Igor Barbosa CATELLANI Daniel Matos SILVA Luiz Fernando CÓTICA Ivair Aparecido dos SANTOS | 2013 | Journal of Advanced Ceramics2013，2，2： | 2 |
| 13 | Role of dynamic computed tomography scans in patients with congenital craniovertebral junction malformations显示文摘AIM To evaluate the role of dynamic computed tomography(CT)scan imaging in diagnosing craniovertebral junction(CVJ)instability in patients with congenital CVJ malformations.METHODS Patients with symptomatic congenital CVJ malformations who underwent posterior fossa decompression and had a preoperative dynamic CT scan in flexion and extended position were included in this study.Measurements of the following craniometrical parameters were taken in flexed and extended neck position:Atlanto-dental interval(ADI),distance of the odontoid tip to the Chamberlain’s line,and the clivus-canal angle(CCA).Assessment of the facet joints congruence was also performed in both positions.Comparison of the values obtained in flexion and extension were compared using a paired Student’s t-test.RESULTS A total of ten patients with a mean age of 37.9 years were included.In flexion imaging,the mean ADI was1.76 mm,the mean CCA was 125.4°and the mean distance of the odontoid tip to the Chamberlain’s line was+9.62 mm.In extension,the mean ADI was1.46 mm(P=0.29),the mean CCA was 142.2°(P<0.01)and the mean distance of the odontoid tip to the Chamberlain’s line was+7.11 mm(P<0.05).Four patients(40%)had facetary subluxation demonstrated in dynamic imaging,two of them with mobile subluxation(both underwent CVJ fixation).The other two patients with a fixed subluxation were not initially fixed.One patient with atlantoaxial assimilation and C23 fusion without initial facet subluxation developed a latter CVJ instability diagnosed with a dynamic CT scan.Patients with basilar invagination had a lower CCA variation compared to the whole group.CONCLUSION Craniometrical parameters,as well as the visualization of the facets location,may change significantly according to the neck position.Dynamic imaging can provide additional useful information to the diagnosis of CVJ instability.Future studies addressing the relationship between craniometrical changes and neck position are necessary. | Otávio Turolo da Silva Enrico Ghizoni Helder Tedeschi Andrei Fernandes Joaquim | 2017 | World Journal of Orthopedics2017，8，3： | 2 |
| 14 | Evolutionary relationships among the primate Mhc-DQA1 and DQA2 alleles 显示文摘 | Kenter M Otting N Anholts J | 1992 | Immunogenetics1992，36，2： | 2 |
| 15 | The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor显示文摘 | Yan Q Matheson C Lopez OT | 1994 | J Neurosci1994，14，9： | 2 |
| 16 | Testosterone and cognition in elderly men:a single testosterone injection blocks the practice effect in verbal fluence,but has no effect on spatial or verbal memory 显示文摘 | Preut R Hellhammer DH | 2000 | Biol Psychiatry2000，47，7： | 1 |
| 17 | Alveolar width distraction osteogenesis for early implant placement显示文摘 | Laster Z Rachmiel A Jensen OT | 2005 | J Oral Maxillofac Surg2005，63，12： | 1 |
| 18 | Effects of temperature on acute toxicity of ammonia to penaeus semisulcatus juveniles显示文摘 | Kumlu MKM Eroldogan OT | 2004 | Aquaculture2004，241，： | 1 |
| 19 | MRI of acute meniscal injury associated with tibial plateau fractures : prevalence, type, and loca- tion显示文摘 | Antti OT Mustonen MP Koivikko J | 2008 | AJR Am J Roentgeno12008，191，4： | 1 |
| 20 | Understanding Bartter syndrome andGitelman syndrome显示文摘 | Fremont OT Chan JC | 2012 | World J Pediatr2012，8，1： | 1 |
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