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| 1 | 甲状腺结节:基于甲状腺癌风险评估的诊断性评价显示文摘甲状腺结节十分常见,通过灵敏的影像学检查在一般人群中的检出率可达到60%以上。大多数患者没有甲状腺相关的临床症状,他们通常在因其他不适就诊检查时发现甲状腺结节。盲目对甲状腺结节进行活检可能造成甲状腺癌的过度诊断,但未能充分完善甲状腺结节活检也可能导致临床漏诊甲状腺癌。最近的临床指南提倡在甲状腺癌风险评估的基础上采用更保守的方法来评估甲状腺结节,即通过临床和超声征象决定活检的必要性。此外,最新证据表明,对于活检无法得出确切结论者,可以通过超声风险分层或其他辅助检查(分子标记物、甲状腺细胞学第二诊疗意见)的联合评估进一步明确甲状腺癌的风险和管理策略。本文总结了对甲状腺结节进行充分评估的临床意义,重点介绍了与明确甲状腺癌风险的诊断性试验相关的临床证据,并强调了在甲状腺癌风险不确定时,考虑患者的价值观和选择倾向的重要性。 | Naykky Singh Ospina Nicole M Iniguez-Ariza M Regina Castro 杨思珏 叶绮婷(译) | 2021 | 英国医学杂志中文版2021，24，9： | 3 |
| 2 | Probiotics for the prevention of pediatric antibiotic-associated diarrhea显示文摘 | Johnston BC Supina AL Ospina M | 2007 | Cochrane Database Syst Rev2007，18，00： | 1 |
| 3 | Probiotics for the prevention of pediatric antibiotic· associated diarrhea显示文摘 | Johnston BC Supina AL Ospina M | 2007 | Coehrane Database Syst Rev2007，，00： | 1 |
| 4 | Meditationpractices for health : state of the research 显示文摘 | Ospina MB Bond K Karkhaneh M | 2007 | Evid RepTechnol Assess (Full Rep)2007，，155： | 1 |
| 5 | Probiotics for the prevention of pediatric antibiotic-associated diarrhea显示文摘 | Johnston BC Supina AL Ospina M | 2007 | Cochrane Database Syst Rev2007，，00： | 1 |
| 6 | Probiotics for the prevention of pediatric anti- biotic associated diarrhea 显示文摘 | JOHNSTON B C SUPINA A L OSPINA M | 2007 | Cochrane Database Syst Rev2007，3，2： | 1 |
| 7 | Risk of bias ver-sus quality assessment of randomised controlled trials : crosssectional study显示文摘 | HARTLING L OSPINA M LIANG Y | 2009 | BMJ2009，339，： | 1 |
| 8 | Clinical trials of meditation practices in health care: characteristics and quality显示文摘 | Ospina MB Bond K Karkhaneh M | 2008 | J Altern Complem Med2008，14，10： | 1 |
| 9 | Olmesartan medoxomil:recent clinical and experimental acquisitions显示文摘 | Destro M Preti P D'ospina A | 2009 | Expert opinion on drug metabolism&toxicology2009，5，9： | 1 |
| 10 | Risk of bias versus quality assessment of randomised controlled trials: cross sectional study 显示文摘 | Hartling L Ospina M Liang Y | 2009 | BMJ2009，339，： | 1 |
| 11 | Key indicators of overcrowdingin Canadian emergency departments: a Delphi study 显示文摘 | Ospina MB Bond K’Schull M | 2007 | CJEM2007，9，5： | 1 |
| 12 | Risk of bias versus quality as?sessment of randomised controlled trials: cross sectional study显示文摘 | Hartling L Ospina M Liang Y | 2009 | BMJ2009，339，： | 1 |
| 13 | Assessment of the relation between biomarkers for smoking and biomarkers for acrylamide exposure in humans 显示文摘 | Vesper HW Bernert JT Ospina M | 2007 | Cancer Epidemiol Biomarkers Prev2007，16，11： | 1 |
| 14 | New in- sights about the bacterial oxidation of arsenopyrite:a min- eralogical scope显示文摘 | MARQUEZ M A OSPINA J D MORALES A L | 2012 | Minerals Engineering2012，39，12： | 1 |
| 15 | Probiotics for the prevention of pediatrec antibiotic-associated diarrhea 显示文摘 | Johnston BC Supina AL Ospina M | 2007 | Cochrane Database Syst Rev2007，18，00： | 1 |
| 16 | Probiotics for the prevention of pediatric antibiotic-associated diarrhea 显示文摘 | Johnston BC Supina AL Ospina M | 2007 | Cochrane Database Syst Rev2007，，00： | 1 |
| 17 | Persistently high venous - to - arterial carbon dioxide differences during early resuscitation are associated with poor outcomes in septic shock显示文摘 | Ospina - Tascrn CA Bautista - Rincrn DF Umafial M | 2013 | Crit Care2013，17，6： | 1 |
| 18 | Clinical trials of meditation practices in health care: characteristics and quality 显示文摘 | Ospina MB Bond K Karkhaneh M | 2008 | J Ahem Complement Med2008，14，10： | 1 |
| 19 | Rhodium catalyzed hydroformylation of β- pinene and camphene: effect of phosphorous ligands and reaction conditions on diastereoselectivity 显示文摘 | Barros H J V Ospina M L Arguello E | 2003 | Journal of Organometalic Chemistry2003，671，12： | 1 |
| 20 | Abeta2s_35j peptide and iron promote apoptosis in lymphocytes by an oxidative stress mechanism: involvement of H2 02 , caspase-3, NF-kappaB, p53 and c- Jun显示文摘 | Velez-Pardo C Ospina G G Jimenez del Rio M | 2002 | Neurotoxicology2002，23，3： | 1 |
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