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| 1 | AHA/ASA关于卒中和短暂性脑缺血发作患者卒中预防推荐的更新显示文摘在卒中和短暂性脑缺血发作(transient ischemic attack,TIA)患者卒中预防推荐发表以后,美国心脏协会和美国卒中协会(American Heart Association/American Stroke Association,AHA/ASA)著述委员会对最近的一些试验结果进行了回顾。本文的目的是对这些新资料做简要回顾、更新某些推荐意见并说明进行这些修改的理由。在2个领域已发表了一些新的重要临床试验结果:(1)在非心源性栓塞所致缺血性卒中或TIA患者卒中二级预防中具体抗血小板药的应用;(2)他汀类药物在预防卒中复发中的应用。 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S. Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm 赵洪芹 李海峰 (译) | 2008 | 国际脑血管病杂志2008，16，4： | 123 |
| 2 | Bile-acid-induced cell injury and protection显示文摘Several studies have characterized the cellular and molecular mechanisms of hepatocyte injury caused by the retention of hydrophobic bile acids (BAs) in cholestatic diseases. BAs may disrupt cell membranes through their detergent action on lipid components and can promote the generation of reactive oxygen species that, in turn, oxidatively modify lipids, proteins, and nucleic acids, and eventually cause hepatocyte necrosis and apoptosis. Several pathways are involved in triggering hepatocyte apoptosis. Toxic BAs can activate hepatocyte death receptors directly and induce oxidative damage, thereby causing mitochondrial dysfunction, and induce endoplasmic reticulum stress. When these compounds are taken up and accumulate inside biliary cells, they can also cause apoptosis. Regarding extrahepatic tissues, the accumulation of BAs in the systemic circulation may contribute to endothelial injury in the kidney and lungs. In gastrointestinal cells, BAs may behave as cancer promoters through an indirect mechanism involvingoxidative stress and DNA damage, as well as acting as selection agents for apoptosis-resistant cells. The accumulation of BAs may have also deleterious effects on placental and fetal cells. However, other BAs, such as ursodeoxycholic acid, have been shown to modulate BA-induced injury in hepatocytes. The major beneficial effects of treatment with ursodeoxycholic acid are protection against cytotoxicity due to more toxic BAs; the stimulation of hepatobiliary secretion; antioxidant activity, due in part to an enhancement in glutathione levels; and the inhibition of liver cell apoptosis. Other natural BAs or their derivatives, such as cholyl-N- methylglycine or cholylsarcosine, have also aroused pharmacological interest owing to their protective properties. | Maria J Perez Oscar Briz | 2009 | World Journal of Gastroenterology2009，15，14： | 53 |
| 3 | Ligation-assisted endoscopic mucosal resection of gastric heterotopic pancreas显示文摘Heterotopic pancreas is a congenital anomaly characterized by ectopic pancreatic tissue.Treatment of heterotopic pancreas may include expectant observation,endoscopic resection or surgery.The aim of this report was to describe the technique of ligation-assisted endoscopic mucosal resection(EMR) for resection of heterotopic pancreas of the stomach.Two patients(both female,mean age 32 years) were referred for management of gastric subepithelial tumors.Endoscopic ultrasound in both disclosed small hypoechoic masses in the mucosa and submucosa.Band ligation-assisted EMR was performed in both cases without complications.Pathology from the resected tumors revealed heterotopic pancreas arising from the submucosa.Margins were free of pancreatic tissue.Ligation-assisted EMR is technically feasible and may be considered for the endoscopic management of heterotopic pancreas. | Mouen A Khashab Oscar W Cummings John M DeWitt | 2009 | World Journal of Gastroenterology2009，15，22： | 25 |
| 4 | Role of IL-10 and TGF-β1 in local immunosuppression in HPV-associated cervical neoplasia显示文摘Cervical cancer is a worldwide disease that constitutes a significant public health problem, especially in developing countries, not only due to its high incidence but also because the most affected population comprises women who belong to marginalized socio-economic classes. Clinical and molecular research has identified immunological impairment in squamous intraepithelial cervical lesions and cervical cancer patients. Human Papillomavirus(HPV) has several mechanisms for avoiding the immune system: it down-regulates the expression of interferon and upregulates interleukin(IL)-10and transforming growth factor(TGF)-β1 to produce a local immunosuppressive environment, which, along with altered tumor surface antigens, forms an immunosuppressive network that inhibits the antitumor immune response. In this review we analyzed the available data on several deregulated cellular immune functions in patients with NIC Ⅰ, NIC Ⅱ and NIC Ⅲ and cervical cancer. The effects of immunosuppressive cytokines on innate immune response, T-cell activation and cellular factors that promote tumor cell proliferation in cervical cancer patients are summarized. We discuss the functional consequences of HPV E2, E6, and E7 protein interactions with IL-10 and TGF-β1 promoters in the induction of these cytokines and postulate its effect on the cellular immune response in squamous intraepithelial cervical lesions and cervical cancer patients. This review provides a comprehensive picture of the immunological functions of IL-10 and TGF-β1 in response to HPV in humans. | Kirvis Torres-Poveda Margarita Bahena-Román Claudia Madrid-González Ana I Burguete-García Víctor Hugo Bermúdez-Morales Oscar Peralta-Zaragoza Vicente Madrid-Marina | 2014 | World Journal of Clinical Oncology2014，5，4： | 21 |
| 5 | High circulating D-dimers are associated with ascites and hepatocellular carcinoma in liver cirrhosis显示文摘AIM: To measure plasma D-dimer levels in cirrhotic patients with and without ascites, assessing the effect of ascites resolution in D-dimer concentration. METHODS: Seventy consecutive cirrhotic patients (M = 44, F = 26, mean age 65 years, SD ± 13), observed from October 2005 to March 2006 were enrolled. Circulating D-dimer levels were measured using a latex-enhanced, immunoturbidimetric test. In patients with ascites (n = 42) the test was repeated after ascites resolution. RESULTS: Ascites was present in 42 patients (group A) and absent in 28 (group B). Group A patients had more advanced liver disease. Hepatocellular carcinoma (HCC) was diagnosed in 14 patients and was more frequent in group B. Above normal range D-dimers were found in 45/70 patients. High D-dimers were more frequent in group A than in group B (P = 0.001). High D-dimers were associated with presence of HCC (P = 0.048) only in group B. After ascites resolution, obtained in all patients, mean D-dimer values decreased in those 34 patients with high basal levels (P = 0.007), returning to normal in 17. CONCLUSION: In patients with liver cirrhosis, ascites and HCC are the main factors associated with increased fibrinolytic activity. | Aldo Spadaro Vincenza Tortorella Carmela Morace Agostino Fortiguerra Paola Composto Caterina Bonfiglio Angela Alibrandi Carmelo Luigiano Giuseppe De Caro Antonino Ajello Oscar Ferraù Maria Antonietta Freni | 2008 | World Journal of Gastroenterology2008，14，10： | 19 |
| 6 | Serrated colorectal cancer: Molecular classification, prognosis, and response to chemotherapy显示文摘Molecular advances support the existence of an alternative pathway of colorectal carcinogenesis that is based on the hypermethylation of specific DNA regions that silences tumor suppressor genes. This alternative pathway has been called the serrated pathway due to the serrated appearance of tumors in histological analysis. New classifications for colorectal cancer(CRC) were proposed recently based on genetic profiles that show four types of molecular alterations: BRAF gene mutations, KRAS gene mutations, microsatellite instability, and hypermethylation of Cp G islands. This review summarizes what is known about the serrated pathway of CRC, including CRC molecular and clinical features, prognosis, and response to chemotherapy. | Oscar Murcia Miriam Juárez Eva Hernández-Illán Cecilia Egoavil Mar Giner-Calabuig María Rodríguez-Soler Rodrigo Jover | 2016 | World Journal of Gastroenterology2016，22，13： | 18 |
| 7 | 社会认知基本维度中文形容词词库的建立显示文摘为建立标准化社会认知基本维度中文形容词词库,以49名大学生为对象对300个备选词语在熟悉度、褒贬度、温暖性和能动性维度上进行评定,最终获得160个词语,其中积极温暖性词汇、消极温暖性词汇、积极能动性词汇和消极能动性词汇各40个.温暖性词汇与能动性词汇在温暖性和能动性含义上差异具有统计学意义;两类词在笔画、频级、熟悉度和褒贬度上匹配较好.熟悉度与褒贬度、能动性和温暖性呈正相关;词语的褒贬度与温暖性、能动性呈正相关,词语的温暖性和能动性相关不具有统计学意义. | 韩梦霏 Oscar Ybarra 毕重增 | 2015 | 西南大学学报(自然科学版)2015，37，8： | 15 |
| 8 | Immunomodulation by mesenchymal stem cells:Interplay between mesenchymal stem cells and regulatory lymphocytes显示文摘Mesenchymal stem cells(MSCs) possess immunomodulatory properties, which confer enormous potential for clinical application. Considerable evidence revealed their efficacy on various animal models of autoimmune diseases, such as multiple sclerosis, systemic lupus erythematosus and uveitis. MSCs elicit their immunomodulatory effects by inhibiting lymphocyte activation and proliferation, forbidding the secretion of proinflammatory cytokines, limiting the function of antigen presenting cells, and inducing regulatory T(Treg) and B(Breg) cells. The induction of Treg and Breg cells is of particular interest since Treg and Breg cells have significant roles in maintaining immune tolerance. Several mechanisms have been proposed regarding to the MSCs-mediated induction of Treg and Breg cells. Accordingly, MSCs induce regulatory lymphocytes through secretion of multiple pleiotropic cytokines, cell-to-cell contact with target cells and modulation of antigen-presenting cells. Here, we summarized how MSCs induce Treg and Breg cells to provoke immunosuppression. | Oscar Ka-Fai Ma Koon Ho Chan | 2016 | World Journal of Stem Cells2016，8，9： | 15 |
| 9 | Targeting cannabinoid signaling for peritoneal dialysisinduced oxidative stress and fibrosis显示文摘Long-term exposure to bioincompatible peritoneal dialysis(PD) solutions frequently results in peritoneal fibrosis and ultrafiltration failure,which limits the life-long use of and leads to the cessation of PD therapy.Therefore,it is important to elucidate the pathogenesis of peritoneal fibrosis in order to design therapeutic strategies to prevent its occurrence.Peritoneal fibrosis is associated with a chronic inflammatory status as well as an elevated oxidative stress(OS) status.Beyond uremia per se,OS also results from chronic exposure to high glucose load,glucose degradation products,advanced glycation end products,and hypertonic stress.Therapy targeting the cannabinoid(CB) signaling pathway has been reported in several chronic inflammatory diseases with elevated OS.We recently reported that the intra-peritoneal administration of CB receptor ligands,including CB_1 receptor antagonistsand CB_2 receptor agonists,ameliorated dialysis-related peritoneal fibrosis.As targeting the CB signaling pathway has been reported to be beneficial in attenuating the processes of several chronic inflammatory diseases,we reviewed the interaction among the cannabinoid system,inflammation,and OS,through which clinicians ultimately aim to prolong the peritoneal survival of PD patients. | Chih-Yu Yang Yat-Pang Chau Ann Chen Oscar Kuang-Sheng Lee Der-Cherng Tarng An-Hang Yang | 2017 | World Journal of Nephrology2017，6，3： | 13 |
| 10 | Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma显示文摘Viral-mediated gene transfer of thymidine kinase ofherpes simplex virus (HSV-tk) has been used to confercytotoxic sensitivity to ganciclovir (GCV) in a variety oftnmor cells. HSV-tk converts GCV into a phosphorylatedcompound which is toxic for dividing cells by blockingDNA synthesis. Our previous study has shown | Miguel Idoate Roberto Bilbao Bruno Sangro Oscar Bruna Jesus Vazquez Jesus Prieto | 1997 | 中国实验血液学杂志1997，5，3： | 13 |
| 11 | 风电氢联产系统功率平滑控制仿真研究显示文摘风能的随机性会引起风力发电出力不平稳,与此同时,电网电压跌落会给风电机组带来脱网运行的风险。针对该问题,文章将电解槽-储氢罐-质子交换膜燃料电池循环系统作为储能装置,接入风力发电系统背靠背变换器直流侧,构成了风电氢联产系统。在风电过剩时,系统通过电解水制氢储存多余电能;在风能不足时,消耗氢气产生电能,补偿不足的有功功率。文章在分析系统构成及运行方式的基础上,设计了各组成单元协调控制策略。MATLAB仿真结果表明:在文章提出的控制策略作用下,系统可以有效地抑制风速随机变化引起的输出功率的波动;配电网电压跌落时,系统具有较强的抵御风机脱网的能力。 | 孟现锋 罗勇 Crisalle Oscar Dardo | 2016 | 可再生能源2016，34，11： | 13 |
| 12 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 13 | 健康生活方式和社会经济状况与死亡和心血管疾病发病风险的关系:基于两项前瞻性队列研究显示文摘目的探究整体生活方式是否可以中介社会经济学地位与死亡和心血管疾病风险的关系,以及生活方式与社会经济学地位的交互作用和联合作用。研究设计来自一般人群的队列研究。参与者来自美国国家健康与营养调查(1988—1994年和1999—2014年)的44462名20岁以上的成年人和来自英国生物银行研究的399537名37~73岁成年人。暴露因素基于家庭收入、职业或就业情况、受教育程度和健康保险(仅美国国家健康与营养调查),利用潜类别分析衡量参与者的社会经济学地位,根据后验概率确定低、中、高水平社会经济学地位。利用吸烟、饮酒、体力活动和膳食质量的信息构建一个健康生活方式评分。主要结局两项研究均关注了全因死亡,而英国生物银行研究还关注了心血管疾病死亡和发病。疾病结局均来自登记系统。结果美国国家健康与营养调查在平均11.2年的随访时间中记录了8906例死亡事件,英国生物银行研究在平均8.8~11.0年的随访时间中记录了22309例死亡事件和6903例心血管疾病病例。与来自高社会经济学地位的成年人相比,来自低社会经济学地位的成年人全因死亡(美国国家健康与营养调查的风险比=2.13,95%可信区间1.90~2.38;英国生物银行研究的风险比=1.96,95%可信区间1.87~2.06)、心血管疾病死亡(风险比=2.25,95%可信区间2.00~2.53)和心血管疾病发病(风险比=1.65,95%可信区间1.52~1.79)风险较高,而生活方式在上述关系中的中介比例分别为12.3%(10.7%~13.9%)、4.0%(3.5%~4.4%)、3.0%(2.5%~3.6%)和3.7%(3.1%~4.5%)。美国国家健康与营养调查中未发现生活方式与社会经济学地位间的交互作用,而在英国生物银行研究,生活方式与结局间的关系在低社会经济学地位的人群中更强。相较于同时拥有高社会经济学地位和3或4个健康生活方式因素的成年人,同时拥有低社会经济学地位和0或1个健康生活方式因素的成年人全因死亡(美国国家健康与营养调查的风险比=3.53,95%可信区间3.01~4.14;英国生物银行研究的风险比=2.65,95%可信区间2.39~2.94)、心血管疾病死亡(风险比=2.65,95%可信区间2.09~3.38)和心血管疾病发病(风险比=2.09,95%可信区间1.78~2.46)风险均更高。结论在美国和英国的成年人中,不健康的生活方式在健康不平等现象中仅起了很小的作用,故单一地促进健康生活方式可能不会大幅减少健康不平等现象,还应同时处理其他决定健康的社会因素。然而,健康生活方式与死亡和心血管疾病风险的保护关联在不同社会经济学地位的人群中稳定存在,这强调了健康生活方式在减轻疾病负担中仍具有重要作用。 | 张言博 陈晨 潘雄飞 郭婧妤 李艳平 Oscar H Franco 刘刚 潘安 | 2021 | 英国医学杂志中文版2021，24，12： | 12 |
| 14 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 15 | Characteristics of developing scour-holes at a sand-embedded cylinder显示文摘Characteristics of developing scour-holes at a sand-embedded 0.2 m diameter circular cylinder are presented. Non-intrusive, high-resolution topographic measurements of developing scour-holes were made with an experimental installation using a laser distance sensor (LDS) and precision step-motors. A clear-water experiment was conducted with bed shear stress equal to 95% of the critical bed shear stress for the initiation of sediment motion at the undisturbed plane sand bed with a d50 of 0.26 mm. During the running experiment of 21 hours duration, measurements were taken by the LDS in different azimuthal half-planes with θ = 0, 15, 30, 45, 60, 75, 90, 105, 120, 135, 150, 165 and 180o in order to study the spatio-temporal variation of geometric properties in developing scour-holes. After 21 hours, the equilibrium condition was approached, with a scour rate less than d50 per hour. Measurement of maximum scour depth in different azimuthal half-planes at different points in time during the experiment show that scour started at the cylinder side and surrounded the cylinder after about 20% of experiment time. Slopes of developing scour-holes presented three regions with different inclinations, which were attributed to vortex action. Both maximum scour depth and maximum scour radius at different azimuthal half-planes are well correlated with the maximum scour depth at plane with θ = 0o. When providing maximum scour depth at the cylinder front, the presented correlations are useful for simple calculation of scour-hole topography. This work provides an experimental database for advanced numerical simulation for loose sediment hydraulics. | Oscar LINK Florian PFLEGER Ulrich ZANKE | 2008 | International Journal of Sediment Research2008，23，3： | 12 |
| 16 | Using old liver grafts for liver transplantation: Where are the limits?显示文摘The scarcity of ideal liver grafts for orthotopic liver transplantation(OLT) has led transplant teams to investigate other sources of grafts in order to augment the donor liver pool. One way to get more liver grafts is to use marginal donors, a not well-defined group which includes mainly donors > 60 years, donors with hypernatremia or macrosteatosis > 30%, donors with hepatitis C virus or hepatitis B virus positive serologies, cold ischemia time > 12 h, non-heart-beating donors, and grafts from split-livers or living-related donations. Perhaps the most practical and frequent measure to increase the liver pool, and thus to reduce waiting list mortality, is to use older livers. In the past years the results of OLT with old livers have improved, mainly due to better selection and maintenance of donors, improvements in surgical techniques in donors and recipients, and intra- and post-OLT management. At the present time, sexagenarian livers are generally accepted, but there still exists some controversy regarding the use of septuagenarian and octogenarian liver grafts. The aim of this paper is to briefly review the aging process of the liver and reported experiences using old livers for OLT. Fundamentally, the series of septuagenarian and octogenarian livers will be addressed to see if there is a limit to using these aged grafts. | Carlos Jiménez-Romero Oscar Caso Maestro Félix Cambra Molero Iago Justo Alonso Cristina Alegre Torrado Alejandro Manrique Municio Jorge Calvo Pulido Carmelo Loinaz Segurola Enrique Moreno González | 2014 | World Journal of Gastroenterology2014，20，31： | 11 |
| 17 | 短期饥饿和再投喂对岩原鲤仔鱼生存生长以及RNA/DNA和RNA/蛋白质比率的影响(英文)显示文摘研究通过对岩原鲤仔鱼在饥饿和再投喂条件下其生存、生长率、RNA/DNA和RNA/蛋白质比率的测定,评估了仔鱼对饥饿的耐受能力和恢复能力。在(19.5±0.5)℃水温下,将岀膜后第16天的岩原鲤仔鱼随机分成6个组:1个持续投饲对照组,实验组分别禁食1、2、3、4、5d后再投喂,实验共进行10d。每天分别从各组取9尾鱼测定体重、体长、RNA、DNA、蛋白质含量。实验结果显示,饥饿处理组仔鱼存活率和以上各项生长指标均随饥饿时间的增加而下降,在恢复投喂后均表现不同程度的补偿生长,其中饥饿1、2、3d的仔鱼在恢复投喂后显示出完全补偿生长,几乎弥补了饥饿所产生的影响,平均终体重与对照组比较无显著差异。饥饿4、5d的仔鱼显示部分补偿生长,恢复投喂只少量减轻了饥饿的影响,平均终体重与对照组相比存在显著差异。饥饿1、2、3d的仔鱼和4、5d的仔鱼在恢复投喂后分别需要1—2d和4d时间才能达到与对照组无显著差异水平。仔鱼生长率变动范围从0.59%到8.00%WW/day,仔鱼RNA/DNA比率、RNA/蛋白质比率与生长率的回归方程为:GR=3.63RNA/DNA 1.74(R2=0.80)和GR=120.14RNA/Protein 2.33(R2=0.31),两种比率均与生长率呈显著线性相关,RNA/DNA比率对生长变化的拟合度更好。结果表明,仔鱼阶段食物缺乏很可能是影响岩原鲤仔鱼存活、生长的主要因素。RNA/DNA更适合作为评定岩原鲤仔鱼营养条件和生长的指标。 | 李云 朱志强 Oscar Ortegón 叶勤 | 2012 | 水生生物学报2012，36，4： | 10 |
| 18 | 单一端元岩浆流体的减压沸腾作用是钨-锡矿形成的一种重要机制显示文摘全球范围内的锡(Sn)和钨(W)矿化普遍与高演化花岗岩有关,但是达到经济品位的矿床较少,且矿化的类型也各有不同,其矿床成因机制一直存在较大争议。近日,《地质学》杂志报道了德国地球科学研究中心的Maximilian Korges等人关于上述问题的研究成果。该团队以位于德国和捷克的Erzgebirge山脉的ZinnwaldS n-W矿床为研究对象,进行了系统的流体包裹体地球化学研究。 | Maximilian Korges Philipp Weis Volker Lüders Oscar Laurent 袁超 | 2018 | 矿物岩石地球化学通报2018，37，2： | 10 |
| 19 | Overall rate, location, and predictive factors for positive surgical margins after robot-assisted laparoscopic radical prostatectomy for high-risk prostate cancer显示文摘我们与高风险的前列腺癌症在 271 个病人报导全面的率,地点和积极外科的边缘(PSM ) 的预兆的因素。在 2008 年 4 月和 2011 年 10 月之间,我们有希望地从作为 D'Amico 分类的病人收集了数据高风险经历了帮助机器人的 laparoscopic 激进分子前列腺切除术。PSM 的全面的率和地点被报导。逐步的逻辑回归模型被适合估计 PSM 的预兆的因素。PSM 的全面的率是 25.1%(271 个病人中的 68 个) 。这些 PSM,(68 中的 26 个)38.2% 是 posterolateral (PL ) , 26.5%(68 中的 18 个) multifocal, 16.2%(68 中的 11 个) 在顶, 14.7%(68 中的 10 个) 在膀胱颈,并且 4.4%(3/68 ) 在另外的地点。有病理学的阶段 pT2 的病人的 PSM 率是 8.6%(140 中的 12 个) , 26.6%(64 中的 17 个) pT3a, 53.3%(32/60 ) pT4 的 pT3b,和 100%(7 中的 7 个) 。在包括 pre- , intra- ,和手术后的参数的一个逻辑回归模型,身体团索引(机会比率[或] :1.09;95% 信心间隔[CI ] :1.01-1.19, P= 0.029 ) ,病理学的舞台(pT3b 或更高对 pT2;或:5.14;95% CI:1.92-13.78;P = 0.001 ) 并且肿瘤的百分比(或:46.71;95% CI:6.37-342.57;P < 0.001 ) 是为 PSM 的独立预兆的因素。在病人在的 PSM 的最普通的地点高风险是 PL 方面,它反映报导肿瘤攻击性。PSM 的唯一的重要预兆的因素是病理学的结果,例如在标本和病理学的舞台的肿瘤的百分比。 | Sung Gu Kang Oscar Schatloff Abdul Muhsin Haidar Srinivas Samavedi Kenneth J Palmer Jun Cheon Vipul R Patel | 2016 | Asian Journal of Andrology2016，18，1： | 9 |
| 20 | 质子交换膜燃料电池建模与控制研究进展显示文摘针对质子交换膜燃料电池的建模与控制问题,概述了基于极化曲线和参数维度的经验模型和机理模型,分析了基于电化学反应、温度、压力等因素的电化学稳态模型和动态模型,介绍了基于神经网络辨识、群集智能算法和支持向量机等的智能方法模型,对质子交换膜燃料电池的现有智能控制策略进行了总结,最后指出:利用群集智能算法同时优化质子交换膜燃料电池的模型参数和环境参数将是建模的一个发展方向,预测广义Hamilton理论等也可被尝试用于质子交换膜燃料电池建模的研究中,同时融合新算法的智能控制策略将成为质子交换膜燃料电池控制的研究趋势. | CRISALLE Oscar Dardo 韩闯 吴莉莉 支长义 | 2015 | 郑州大学学报(工学版)2015，36，6： | 8 |
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