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| 1 | 腔内介入治疗血管性勃起功能障碍显示文摘过去一个世纪里,勃起功能障碍(ED)的治疗一直是一件引人关注的事情,涉及到泌尿、心血管以及手术领域的多个学科。随着ED与心血管疾病的相关性被充分证实,血管造影技术已被用来鉴别血管性阳痿。由于腔内血管药物洗脱支架植入术在治疗冠状动脉疾病获得成功,采用该技术来治疗血管性ED已激起了医务人员的浓厚兴趣。最近报道了针对阴茎流入血管狭窄的男性,植入药物洗脱支架绕过病变处动脉已获得了较高的成功率。同样,血管内栓塞治疗静脉闭塞功能障碍也取得了惊人的手术成功率。然而,查阅文献发现动脉介入只推荐应用于治疗年轻的孤立性血管损伤的患者,通常为那些先前经历过创伤的患者。该手术的短期功能恢复没有达到最佳,长期疗效也有待进一步观察。总之,用微创方法治疗勃起功能障碍的希望仍然存在,但是在获得普遍认可之前仍需要进一步的研究。 | Edward D Kim Ryan C Owen Gregory S White Osama O Elkelany Cyrus D Rahnema | 2015 | Asian Journal of Andrology2015，17，1： | 3 |
| 2 | In vitro and in vivo effects of ferulic acid on gastrointestinal motility:Inhibition of cisplatin-induced delay in gastric emptying in rats显示文摘AIM: To study the effects of ferulic acid on gastrointe-stinal motility both in vitro and in vivo.METHODS: Ferulic acid induced concentration-dependent stimulation of the basal tone of isolated guinea pig ileum (2-20 μmol/L) and isolated rat fundus (0.05-0.4 mmol/L). RESULTS: Ferulic acid significantly accelerated the gastrointestinal transit and gastric emptying in rats in a dose-dependent manner (50-200 mg/kg, po). Cisplatin (2.5-20 mg/kg, ip) induced a dose-dependent delay in gastric emptying in rats. Pretreatment with ferulic acid dose-dependently, significantly reversed the cisplatin-induced delay in gastric emptying. CONCLUSION: The endogenous prostaglandins (PGs) are involved in mediating the stimulant effects of ferulic acid. This effect of dietary ferulic acid may help improve other accompanying gastrointestinal symptoms such as abdominal discomfort and also may protect against emesis induced by cytotoxic drugs. | Osama A Badary Azza S Awad Mohey A Sherief Farid MA Hamada | 2006 | World Journal of Gastroenterology2006，12，33： | 2 |
| 3 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 4 | Lymphocytic colitis: A clue to bacterial etiology显示文摘AIM: To find out the role of bacteria as a possible etiological factor in lymphocytic colitis.METHODS: Twenty patients with histopathological diagnosis of lymphocytic colitis and 10 normal controls were included in this study. Colonoscopic biopsies were obtained from three sites (hepatic and splenic flexures and rectosigmoid region). Each biopsy was divided into two parts. A fresh part was incubated on special cultures for bacterial growth. The other part was used for the preparation of histologic tissue sections that were examined for the presence of bacteria with the help of Giemsa stain.RESULTS: Culture of tissue biopsies revealed bacterial growth in 18 out of 20 patients with lymphocytic colitis mostly Escherichia coli(14/18), which was found in all rectosigmoid specimens (14/14), but only in 8/14 and 6/14 of splenic and hepatic flexure specimens respectively. In two of these cases, E coliwas associated with proteus. Proteus was found only in one case, Klebsiella in two cases, and Staphylococcus aureus in one case. In the control group, only 2 out of 10 controls showed the growth of E coliin their biopsy cultures.Histopathology showed rod-shaped bacilli in the tissue sections of 12 out of 14 cases with positive E coliin their specimen's culture. None of the controls showed these bacteria in histopathological sections.CONCLUSION: This preliminary study reports an association between E coliand lymphocytic colitis, based on histological and culture observations. Serotyping and molecular studies are in process to assess the role of E coliin the pathogenesis of lymphocytic colitis. | Thanaa EA Helal Naglaa S Ahmed Osama Abo El Fotoh | 2005 | World Journal of Gastroenterology2005，11，46： | 2 |
| 5 | Imaging strongly scattering media using a multiple frequency distorted born iterative method 显示文摘 | Osama S Haddadin | 1998 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control1998，45，6： | 1 |
| 6 | Characterization of an allelic series in the MONOPTEROS gene of Arabidop- sis显示文摘 | OSAMA O JASON G MEGAN G S | 2013 | Genesis2013，52，2： | 1 |
| 7 | Response to intra-arterial and combined intravenous and intra-arterial thrombolytic therapy in patients with distal internal carotid artery occlusion 显示文摘 | Osama OZ Jose IS Concepcion S | 2002 | Stroke2002，33，： | 1 |
| 8 | Quantitative characterizationof mixing of free-flowing granular material in tote (bin)-blenders显示文摘 | OSAMA S COFFIN-BEACH D MUZZIO F J | 2002 | PowderTechnology2002，126，： | 1 |
| 9 | Cerebral blood flow velocity in a- cute schizophrenia patients:a transcranial doppler uhrasonography study 显示文摘 | Ammar O Jurgen K Osama S | 1998 | Journal of the Amercian Heart Association1998，29，： | 1 |
| 10 | Minimum-cost canal cr- oss section显示文摘 | Ghazaw Y Salem Ariel A S Osama K | 2000 | Alexandria Engineering Journal2000，39，1： | 1 |
| 11 | Hemodialysis in management of hypothermia显示文摘 | Owda A Osama S | 2001 | Am J Kidney Dis2001，38，2： | 1 |
| 12 | Quantitative characterization of mixing of free-flowing granular material in the tote (bin)-blenders 显示文摘 | Osama S S Coffin B D Muzzio F J | 2002 | Powder Technology2002，126，2： | 1 |
| 13 | Freauency- scalable SiGe bipolar RF front-end design 显示文摘 | SHANA' s Osama LINSCOTT Ivan TYLER Len | 2001 | Journal of Solid-State Circuit2001，36，6： | 1 |
| 14 | A behavior and delay equivalent petri net model for performance evaluation of communication 显示文摘 | Osama S Youness Wail S El-Kilani Waiel F Abd El-Waheda | 2008 | Computer Communications (S0140-3664)2008，31，10： | 1 |
| 15 | Styrene synthesis: high conversion over unpromoted iron oxide catalysts under practical working conditions显示文摘 | OSAMA S WOLFGANG R ACHIM S | 2003 | Angew Chem Int Edit2003，42，46： | 1 |
| 16 | Hot melt extrusion: an emerging drug delivery technology 显示文摘 | Andrews G P J David S Osama A M | 2009 | Pharm Tech Eur2009，21，1： | 1 |
| 17 | Testosterone,sex hormone-binding globulin,and the development of type 2 diabetes in middle-aged men显示文摘 | Henry A F Osama h | 2000 | Diabetes Care2000，23，4： | 1 |
| 18 | Quantitative characterization of mixing processes in rotary calciners 显示文摘 | Osama S Sudah Chester A W Kowalski J A | 2002 | Powder technology2002，126，： | 1 |
| 19 | Energy method for incremental collapse analysis of framed structures显示文摘 | Sidney A G Thomas E Osama S | 1988 | Journal of Structural Engineering1988，114，1： | 1 |
| 20 | A thermal creep model for the contact of nominally flat surfaces: Jeffreys ' linear visco-elastic model显示文摘 | Abuzeid Osama M Hashem S Alkhaldi Peter Eberhard | 2011 | International Journal of Mechanical Sciences2011，53，10： | 1 |
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