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| 1 | More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus显示文摘Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted. | Santosh K Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala Kamala Andrzej Ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius | 2019 | General Psychiatry2019，32，4： | 11 |
| 2 | Primary gastric mucosa associated lymphoid tissue lymphoma: Clinical data predicted treatment outcome显示文摘AIM: To determine clinical characteristics and treatment outcome of gastric lymphoma after chemotherapy and immuno-chemotherapy. METHODS: Thirty four patients with primary gastric mucosa associated lymphoid tissue (MALT) lymphoma (Ann Arbor stages Ⅰ to Ⅳ) were enrolled. All had upper gastric endoscopy, abdominal ultrasonography, CT and H pylori status assessment (histology and serology). After anti-H pylori treatment and initial chemotherapy, patients were re-examined every 4 mo. RESULTS: Histological regression of the lymphoma was complete in 22/34 (64.7%) and partial in 9 (26.5%) patients. Median follow up time for these 31 responders was 60 mo (range 48-120). No regression was noted in 3 patients. Among the 25 (73.5%) H pylori positive patients, the eradication rate was 100%.CONCLUSION: Using univariate analysis, predictive factors for overall survival were international prognostic index (IPI) score, hemoglobin level, erythrocyte sedimentation rate (ESR), and platelet numbers (P < 0.005). In addition to this, Cox proportion hazard model differentiate IPI score, ESR, and platelets as predictors of survival. | Milena Todorovic Bela Balint Miodrag Jevtic Nada Suvajdzic Amela Ceric Dragana Stamatovic Olivera Markovic Maja Perunicic Slobodan Marjanovic Miodrag Krstic | 2008 | World Journal of Gastroenterology2008，14，15： | 10 |
| 3 | Noninvasive diagnosis of vulnerable coronary plaque显示文摘Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease.For this reason,screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine.Necropsy studies have described histopathological changes associated with the development of acute coronary events.In this regard,thin-cap fibroatheroma has been identified as the main vulnerable coronary plaque feature.Hence,many imaging techniques,such as coronary computed tomography,cardiac magnetic resonance or positron emission tomography,have tried to detect noninvasively these histomorphological characteristics with different approaches.In this article,we review the role of these diagnostic tools in the detection of vulnerable coronary plaque with particular interest in their advantages and limitations as well as the clinical implications of the derived findings. | Eduardo Pozo Pilar Agudo-Quilez Antonio Rojas-González Teresa Alvarado María José Olivera Luis Jesús Jiménez-Borreguero Fernando Alfonso | 2016 | World Journal of Cardiology2016，8，9： | 4 |
| 4 | A further study of the kinetics and optimization of the essential oil hydrodistillation from lavender flowers显示文摘Hydrodistillation has commonly been used to recover essential oil from various plant materials,including lavender(Lavandula officinalis) flowers.The main objectives of the present study were to model the kinetics of the lavender essential oil(LEO) hydrodistillation using a phenomenological model,to evaluate the statistical significance of the hydromodule and hydrodistillation time on LEO yield combining a 4~2 full factorial design with the response surface methodology,to model statistically LEO yield by multiple non-linear regression and to determine the optimal process conditions that provided the maximum LEO yield.The fast-essential oil distillation(washing stage) in the initial period and the slow diffusion stage until the saturation occurring simultaneously were observed,justifying the use of the phenomenological model.With increasing the hydromodule,the saturation LEO yield and the washable fraction of the LEO decreased while the washing and diffusion rate constants increased.Knowledge of the LEO oil yield and the hydrodistillation kinetics is important from the techno-economical point of view. | Aleksandra Perovic Mihajlo Z.Stankovic Vlada B.Veljkovic Milan D.Kostic Olivera S.Stamenkovic | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 3 |
| 5 | 经皮经导管射频消融去肾交感神经术与螺内酯对难治性高血压昼夜节律和血压变异性的影响显示文摘经皮经导管射频消融去肾交感神经术(sympathetic renal denervation,SRD)可作为药物控制不佳的难治性高血压患者的一种替代治疗方法,SRD对减少短期血压变异性(blood pressure variability,BPV)有效。然而,这个作用尚未在随机对照试验中证实。本研究旨在比较螺内酯和SRD对昼夜血压和BPV的影响。方法:对一项随机试验进行析因分析, | de la Sierra A Pareja J Armario P Barrera Yun S Vázquez S Sans L Pascual J Oliveras A 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 6 | Mitotic crossover- an evolutionary rudiment which promotes carcinogenesis of colorectal carcinoma显示文摘Mitotic crossover is a natural mechanism that is a main source of the genetic variability of primitive organisms.In complex organisms such as mammals,it represents an evolutionary rudiment which persisted as one of the numerous DNA repair mechanisms,and results in the production of homozygous allele combinations in all heterozygous genes located on the chromosome arm distal to the crossover.This event is familiar as loss of heterozygosity,which is one of the key mechanisms responsible for the development and progression of almost all cancers.We propose the hypothesis in which mitotic crossover is a principal source of the increased loss of heterozygosity that leads to the initiation and progression of colorectal carcinoma.The hypothesis could be tested by in vitro inhibition of Rad51 protein,orthotopic grafting of human colon cancer tissue into the gut of mice,and treatment with potential inhibitors.After these procedures,the frequency of mitotic crossover would be estimated.The development of selective inhibitors of mitotic crossover could stop further carcinogenesis of colorectal carcinoma,as well as many other neoplastic events.Loss of heterozygosity is an event responsible for carcinogenesis,its reduction by selective inhibitors of mitotic crossover could have a positive effect on cancer chemoprevention,as well as on growth reduction and a cessation in the progression of earlier developed tumors. | Branislav Rovcanin Ivan Ivanovski Olivera Djuric Dimitrije Nikolic Jelena Petrovic Petar Ivanovski | 2014 | World Journal of Gastroenterology2014，20，35： | 2 |
| 7 | Effects of organic pollution on transplanted aquatic bryophytes 显示文摘 | MARTINE Abaigar J NUNEZ Olivera E SANCHEZ Diaz M | 1993 | J Bryol1993，17，4： | 2 |
| 8 | Cross-Sectional Survey on Complementary and Alternative Medicine Awareness among Health Care Professionals and Students Using CHBQ Questionnaire in a Balkan Country显示文摘在互补、其他的药(凸轮) 的态度,知识,和使用上进行研究的目的在塞尔维亚的治疗。关于在这个区域的凸轮治疗的可得到的数据是少见的,意见从健康缺乏扇区。巴尔干的区域国家在在凸轮治疗上发出国家政策有延期。使用的问询表基于的方法以前验证了凸轮健康信仰问询表(CHBQ ) ,作为 5 条款 Likert 类型规模提出了,为本地环境调整了。护理学生和专业人员被评估。问询表在凸轮治疗的态度,知识和使用上理解 10 个关上的问题。这调查在塞尔维亚的八个城市里被进行, 1 月 2010July 日 2011。797 个参加者的一个总数被包括。秒组参加者是 145 个保健专业人员(50 学术职员, 64 临床的职员, 19 个药剂师, 6 位另外的临床的分支专家和 6 个护士) 。数据被会见收集。应试者能获得 70 个点的最大值, 35 代表中立态度。牙科的结果学生(54.65 换 ???? , | Mihajlo B Jakovljevic Vera Djordjevic Veroljub Markovic Olivera Milovanovic Nemanja K Rancic Snezana M Cupara | 2013 | Chinese Journal of Integrative Medicine2013，19，9： | 2 |
| 9 | Expression of cytokeratins in Helicobacter pylori-associated chronic gastritis of adult patients infected with cagA+strains:An immunohistochemical study显示文摘瞄准:为了与长期的胃炎在成年病人的胃的上皮调查不同 cytokeratins (CK ) 的表示,与 Helicobacter pylori (H pylori ) 感染了 cagA+ 紧张。方法:CK 7 的表示, 8, 18, 19 和 20 在 84 个病人的窦的胃的活体检视组织化学地是学习免疫。所有 CK 是在 cagA+H pylori 胃炎(57 个案例) 染色的免疫, non-H pylori 胃炎(17 个案例) 和正常胃粘膜(10 个案例) 。结果:在 cagA+ H pylori 胃炎, CK8 从表面上皮可比较地被表示到正常的窦粘膜到深腺。CK18 和 CK 19 的分发是未改变的,即表示的 transmucosal,而是紧张在与正常相比的小凹的区域是不同的胃粘膜。Cytokeratin 18 免疫反应在与 H pylori 否定的胃炎和控制相比的 H pylori 积极的胃炎的小凹的上皮是显著地更高的。相反,在 CK19 免疫反应的减少发生在 H pylori 积极的胃炎的小凹的上皮。在没有 H pylori 感染的正常、煽动的窦粘膜, CK20 在表面上皮和上面的小凹的区域强烈 / 中等并且同类地被表示,但是在 H, pylori 导致了胃炎在小凹的区域的表示的重要减少被注意。通常,在正常窦的粘膜和 H pylori 否定的胃炎,, CK7 的表示没被观察在关于半 cagA+ , H 感染 pylori 的病人,节制颈的焦点的 CK7 免疫反应,卷的腺区域被登记,特别在区域与更严重煽动性渗入。结论:在 CK 7 的表示的改变, 18, 19 和 20 在感染 cagA+ 紧张的成年病人和 CK8 的正常表示发生在 H 联系 pylori 的长期的胃炎的窦粘膜。在不同 cytokeratins 表示力量的改变贡献在 H 感染 pylori 的胃粘膜观察的上皮的紧密的连接变弱。 | Vera Todorovic Neda Drndarevic Olivera Mitrovic Institutefor MedicalResearch Aleksandra Sokic-Milutinovic Tomica Milosavljevic Marjan Micev Ivan Nikolic Thomas Wex Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，12： | 2 |
| 10 | Impedance microbiology: quantification of bacterial content in milk by means of capacitance growth curves显示文摘 | Felice C J Madrid R E Olivera J M | 1999 | J Microbiological Methods1999，35，： | 1 |
| 11 | Memory System in Organizations:An Empirical Investigation of Mechanisms for Knowledge Collection显示文摘 | Fernando Olivera | 2000 | Storage and Access Journal of Management Studies2000，37，6： | 1 |
| 12 | Aldosterone regulates Na,K-ATPase and increases lung edema clearance in rats显示文摘 | Olivera WG Ciccolella DE Barquin N | 2000 | Am J Respir Crit Care Med2000，161，： | 1 |
| 13 | Memory System in Organizations: An Empirical Investigation of Mechanisms for Knowledge Collection显示文摘 | Fernando Olivera | 2000 | Storage and Access Journal of Management Studies2000，37，6： | 1 |
| 14 | Alpha S-conotoxin RVIIIA:a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors显示文摘 | Teichert RW Jimenez EC Olivera BM | 2005 | Biochemistry2005，44，21： | 1 |
| 15 | The square - root law of precautionary reserves 显示文摘 | Olivera J H G | 1971 | Journal of Political Economy1971，79，： | 1 |
| 16 | Open ring imaging sign: highly specific for atypical brain demyelination 显示文摘 | Masdeu JC Quinto C Olivera C | 2000 | Neurology2000，54，： | 1 |
| 17 | Increased pulse pressure is associated with left atrial enlargement in resistant hypertensive patients显示文摘 | Armario P Oliveras A Hernandez-Del-Rey R | 2013 | Blood Press2013，22，1： | 1 |
| 18 | Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegeneractive diseases 显示文摘 | Rego AC Olivera CR | 2003 | Neurochem Res2003，28，10： | 1 |
| 19 | Peptide toxins from Conus geographus venom 显示文摘 | Gray W R Luque A Olivera B M | 1981 | J Biol Chem1981，256，： | 1 |
| 20 | Preimplantation genetic diag- nosis for gender selection in the USA显示文摘 | Colls P Silver L Olivera G | 2009 | Reprod Biomed On- line2009，19，2： | 1 |
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