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266篇 您的检索式:作者名="OLIVARES M"
    题名 作者 年代 出处 被引量
1Conversion from calcineurin inhibitors to mTOR inhibitors stabilizes diabetic and hypertensive nephropathy after liver transplant显示文摘AIM: To investigate if conversion to the mammalian target of rapamycin inhibitors(mTORi) improves renal function in diabetic and/or hypertensive liver transplant patients immunosuppressed with tacrolimus or cyclosporine.METHODS: The study included 86 liver graft recipients immunosuppressed with mTORi treatment after orthotopic liver transplantation(OLT), including all liver recipients with worsening renal function before conversion to mTORi(n = 55 patients) and recipients with normal renal function who converted to m TORi for other reasons(n = 31 patients). We identified patients with diabetes mellitus(n = 28), arterial hypertension(n = 27), proteinuria(n = 27) and all three factors(n = 8)(some patients have hypertension and diabetes and no proteinuria). The primary endpoint was evolution in renal function defined as the development in plasma creatinine as a function of diabetes mellitus(DM), hypertension(HT) or proteinuria. We required elevated serum creatinine for at least two weeks to define renal dysfunction.RESULTS: Only patients that converted because of renal failure with plasma creatinine levels > 1.5 mg/dL showed an improvement of renal function(2.14 to 1.77 mg/dL)(P = 0.02). Patients with DM showed no improvement of serum creatinine levels(1.31 mg/dL to 1.37 mg/dL) compared with non DM patients(1.31 mg/dL to 1.15 mg/dL)(P = 0.01), HT patients(1.48 mg/dL to 1.5 mg/dL) with non HT patients(1.21mg/d L to 1.08 mg/dL) and patients with proteinuria(1.44 mg/dL to 1.41 mg/dL) and no proteinuria(1.31 mg/dL to 1.11 mg/dL). CONCLUSION: In OLT recipients with diabetes or hypertensive nephropathy, conversion to m TORi does not improve renal function but stabilizes plasma levels of creatinine. Proteinuria is not a contraindication to conversion to m TORi; it also stabilizes renal function. Conversion to m TORi should only be avoided in patients with diabetes, hypertension and proteinuria.José M álamo Claudia Olivares Lydia Barrera Luis M Marín Gonzalo Suarez Carmen Bernal Juan Serrano Jordi Muntané Francisco J Padillo Miguel A Gómez 2015World Journal of Transplantation2015,5,1:6
2In vivo correetion of routine hereditary tyrosinemia type I by phiC31 integrase-mediated gene delivery 显示文摘Held P K Olivares E C Grompe M 2005Mol Ther2005,11,3:1
3Evaluation of fungal-and photo-degradation as potential treatments for the removal of sunscreens BP3 and BPI 显示文摘GAGO-FERRERO P BADIA-FABREGAT M OLIVARES A 2012Science of the Total Environment2012,427,15:1
4Essentiality of copper in humans显示文摘UAUY R OLIVARES M MAURICIO G 1998Am J Clin Nutr1998,,:1
5Antimicrobial susceptibility of Helicobacter pylori and mechanisms of clarithromycin resistance in strains isolated from patients in Uruguay显示文摘Torres-Debat M E Prez-Prez G Olivares A 2009Rev Esp Enferm Dig2009,101,5:1
6Risks and benefits of copper in light new insights of copper homeostasis 显示文摘De Romana DL Olivares M Uauy R 2011J Trace Elem Med Biol2011,25,1:1
7A Centralized Energy Management System for Isolated Microgrids显示文摘OLIVARES D E CANIZARES C A KAZENRANI M 2014IEEE Transactions on smart grid2014,5,4:1
8Biomass gasification : Produced gas upgrading by in-bed use of dolomite显示文摘Olivares A Aznar M P Caballero M A 1997Ind Eng Chem Res1997,36,:1
9Benefi- cial Effects of Probiotic Bacteria Isolated from Breast Milk 显示文摘LARA-VILLOSLADA F OLIVARES M SIERRA S 2007British Journal of Nutrition2007,,98:1
10Cloning and identification of conjugative transfer origins in the Rhizobium meliloti genome显示文摘HERRERA-CERVERA J A SANJUAN-PINILLA J M OLIVARES J 1998J Bacteriol1998,180,:1
11Determination of unsaturation grade and trans isomers generated during thermal oxidation of edible oils and fats by FTIR显示文摘MORENO M M C M OLIVARES M D LOPEZ A F J 1999J Mol Struct1999,,:1
12A grain conductivity approch to shaly sandstones显示文摘Olivar A L De Lima Mukul M 1990Geophysics1990,55,10:1
13Controlled production of aligned-nanotube bundles 显示文摘Terrones M Grobert N Olivares J 1997Nature1997,388,6037:1
14Transcriptional and posttranslational upregulation of HER3(ErbB3) compensates for inhibition of the HER2 tyrosine kinase显示文摘GARRETT J T OLIVARES M G RINEHART C 2011Proc Natl Acad Sci2011,108,12:1
15Determination of unsaturation grade and trans isomers generated during thermal oxidation of edible oils and fats by P'TIR显示文摘MOYA MORENO C M MENDOZA OLIVARES D AMEZQUITA LOPEZ J V 1999Journal of Molecular Structure1999,482,1:1
16Effects of a selective cy clooxygenase-2 inhibitor on endometrial epithelial cells from pa tientswith endometriosis 显示文摘Olivares C Bilotas M Buquet R 2008Hum Reprod2008,23,12:1
17The inhibitory effect of cele- coxib and rosiglitazane on experimental endometriosis 显示文摘Olivares C Ricci A Bilotas M 2011Fertil Steril2011,96,2:1
18Static and Dynamic Behavior of Recycled Tyre Rubber-filled Concrete 显示文摘Hernandez Olivares F Barluenga G Bollatib M 2002Cement Concrete Res2002,32,10:1
19Antimicrobial potential of four Lactobacillus strains isolated from breast milk 显示文摘OLIVARES M DIAZ-ROPERO M P MARTIN R 2006J Appl Microbiol2006,101,1:1
20Characterization of a reuterin-producing Lactobacillus coryniformis strain isolated from a goat’s milk cheese显示文摘Martín R Olivares M Martín M L 2005International Journal of Food Microbiology2005,104,3:1
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