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| 1 | 猪生长激素基因第二外显子区遗传变异的序列基础显示文摘采用聚合酶链反应(PCR)及PCR产物的直接序列分析方法,对猪生长激素基因第二外显子区遗传变异的序列基础进行了研究。PCR扩增片段长度为230bp,包含全部的生长激素基因的第二外显子区序列(161bp)。共分析了6头二花脸和6头长白猪,结果表明:在猪的生长激素基因第二外显子区,共有7处碱基替换,依次为507处的C/T替换、520处的C/T替换、546处的G/A替换、555处的G/A替换、556处的C/A替换、595处的C/T替换及634处的C/T替换。只有507、546、555和556处的突变可引起氨基酸序列的变异,其余均为无意义突变。采用GCG软件包对限制酶酶切图谱进行分析。 | 姜志华 Rott.,OJ | 1997 | 南京农业大学学报1997，20，2： | 21 |
| 2 | MODELLING AND STABILITY ANALYSIS OF POPULATION GROWTH WITH SPATIAL DIFFUSION显示文摘In recent years, population growth models with spatial diffusion have beenextensively studied by many authors (for example, see [1-5]). In this paper, a populationgrowth model is considered with a discrete age-dependence and spatial diffusion, and isinvestigated in a semigroup framework. The spectral properties of the population oper-ator are given. On the basis of such spectral consideration, the asymptotic behaviourof the semigroup generated by the population operator is obtained. Finally, a nonlinearpopulation growth model is considered and its stability is analyzed. | W.L.CHAN FENG Dexing Department of Mathematice,the Chinese University of Hong Kong,Shatin,N.T,Hong Kong Institute oj Systems Science, Academia Sinica, Beijing 100080, China | 1993 | Systems Science and Mathematical Sciences1993，6，4： | 10 |
| 3 | Antioxidant, hepatoprotective and hypolipidemic effects of methanolic root extract of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication显示文摘Objective: To evaluate in vivo antioxidant and hepatoprotective activities of the methanolic extract of the root of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication. Methods: Malondialdehyde (MDA), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin as indices of liver damage and lipid peroxidation were detected in rats after intraperitoneal administration of extract (5 mg/kg). Results: The liver, kidney and heart showed significant reduction ( P <0.05) in the levels of MDA from (0.18依0.04), (0.23 依0.07) and (0.26依0.10) nmol/mg respectively in the CCl 4 control to (0.15依0.03), (0.17依0.04) and (0.17 依0.07) nmol/mg protein in groups pre-treated with the extract for three days at 5 mg/kg). Similarly, compared to the CCl 4 control, significant reduction ( P<0.05) in serum AST, ALT and bilirubin as well as in level of total cholesterol and MDA with concomitant increase in HDL cholesterol, superoxide dismutase and catalase levels when CCl 4 -intoxicated rats were treated with Cassia singueana root extract for two weeks. Conclusions: These results suggest that methanolic extract of Cassia singueana contain potent antioxidant compounds that can offer significant protection against hepatic and oxidative injuries. | Ottu OJ Atawodi SE Onyike E | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，8： | 5 |
| 4 | Fluid-Rock Interaction of Shear Zones in Continental Crust:as Evidenced by Xincheng-Xishui and Hetai Shear Zones显示文摘There is a coupling of thermal, mechanical, chemical and fluidal processes in a continental shear zone. Both Xincheng-Xishui and Hetai shear zones are typical continental crust shear zones of greenschist facies environment. The representative mylonite zones of the shear zones are studied with whole rock major and trace element analyses. The chemical compositional variation tendencies in both shear zones are very similar and the gain-loss ratios of various components in the mylonitic rocks are reflected in the mass balance equations. The enrichment of those immobile high-field-strengh elements is considered to he related to the volume loss of the myionitic rocks in a shear zone. Based on the volume loss expression Cs/Co=1/(1-V),the fractional volume losses (V)are 37.5% and 36.5%-42.3% respectively for mylonites and ultramylonites in the Xincheng-Xishui shear zone and 11% and 28% respectively for mylonites and phyllonites in the Hetai shear zone. The high volume loss and large removal of SiO2 | Zhong Zengqiu You Zhendong Xu QidongFaculty oj Earth Sciences, China University of Geosciences, Wuhan 430074 | 1995 | Journal of Earth Science1995，14，2： | 4 |
| 5 | Spectrofluorimetric determination of zinc(Ⅱ)with N-salicylidene phenylalanine显示文摘Spectrofluorimetricdeterminationofzinc(Ⅱ)withN-salicylidenephenylalanineLiuShaopu;WangLujun;ZhouGuangming(InstttvteojEnvironm... | Liu Shaopu Wang Lujun Zhou Guangming(Instttvte oj Environmental Chemistry, Souxthwest Mormal University,Chongqing 630715) | 1995 | 西南师范大学学报(自然科学版)1995，20，4： | 3 |
| 6 | The developmental fate of green fluorescent mouse embryonic germ cells in chimeric embryos显示文摘Primordial germ cells (PGCs), as precursors of mam-malian germ lineage, have been gaining more attention as anew resource of pluripotent stem cells, which bring a greatpossibility to study developmental events of germ cell invitro and at animal level. EG4 cells derived from 10.5 dayspost coitum (dpc) PGCs of l29/svJ strain mouse wereestablished and maintained in an undifferentiated state.With an attempt to study the differentiation capability ofEG4 cells with a reporter protein: green fluorescence pro-tein, and the possible application of EG4 cells in the re-search of germ cell development, we have generated severalEG4-GFP cell lines expressing enhanced green fluorescenceprotein (EGFP) and still maintaining typicaI characteris-tics of pluripotent stem cells. Then, the differentiation ofEG4-GFP cells in vitro as well as their developmental fatein chimeric embryos which were produced by aggregatingEG4-GFP cells to 8-cell stage embryos were studied. Theresults showed that EG4 cells carrying green fluorescencehave a potential use in the research of germ cell develop-ment and other related studies. | XU XIN YONG SHEN YU HSIAO CHlEN TSUNGSUMIO SUGANO YUAN CHANG YAN(Shanghai Institute of Cell BiolOgy, Chinese Academy ofScience, Shanghai 200031, China)(Department of Virology, The Institute oj Medical Sci-ence) The University of Tokyo, Tokyo, Japan) | 1999 | Cell Research1999，9，3： | 3 |
| 7 | 肝脏和胰腺创伤的分类(综述)显示文摘 肝脏是腹部外伤中最常见的易损脏器之一,尤其在合并其他器官损伤时,其并发症的发生率和死亡率较高.胰腺外伤性损伤少见且表现隐匿,常合并其他腹腔内脏器损伤,因其有类似实性或空腔脏器损伤的特点,这种少见的病变常表现出很高的并发症发生率和死亡率.本文作者重点综述了用于肝脏和胰腺创伤的各种分类方法和临床应用评估.…… | Oniscu GC Parks RW Garden OJ 邹一平(摘) | 2006 | 中华肝胆外科杂志2006，12，8： | 3 |
| 8 | Gel-microemulsion as vaginal spermicides and intravaginal drug delivery vehicles显示文摘 | D'Cruz OJ Uckun FM | 2001 | Contraception2001，64，： | 2 |
| 9 | Marrow stromal cells as stem cells for nonhematopoietic tissues显示文摘 | Prockop OJ | 1997 | Science1997，276，： | 2 |
| 10 | Cyclin B1 and other cyclins as tumor antigens in immunosurveillance and immunotherapy of cancer显示文摘 | Egloff AM Vella LA Finn OJ | 2006 | Cancer Res2006，66，： | 1 |
| 11 | Iatrogenic injury to the bile duct显示文摘 | Garden OJ | 1991 | Br J Surg1991，78，12： | 1 |
| 12 | Cardiopulmonary and Systemic effects of methylprednisolone in patients undergoing cardiac surgery 显示文摘 | Liakopoulos OJ Schmitto JD Kazmaier S | 2007 | Ann Thorac Surg2007，84，7： | 1 |
| 13 | Dysregulation of beta-catenin expression correlates with tumor differentiation in pancreatic duct adenocarcinoma显示文摘 | Lowy AM Fenoglio-Preiser C Kim OJ | 2003 | Ann Surg Oncol2003，10，3： | 1 |
| 14 | In vitro cultivation of Microphallus turgidus ( Trematoda : microphalldae) from metacercaria to ovigerousadult with continuation of the life cycle in the laboratory 显示文摘 | Pung OJ Burger AR Walker MF | 2009 | J Parasitol2009，95，4： | 1 |
| 15 | Oxidative mechanisms of brain dysfunction during sepsis显示文摘 | Dal-Pizzol F Ritter C Cassol-Jr OJ | 2010 | Neurochem Res2010，35，1： | 1 |
| 16 | Hea, d-to-hea, dcomparison of N-terminal pro-brain natrJuretic peptide, brain natriuretic peptide and N-terminal pro-atrial natiriuretic peptide in diagnosing left ventricular dysfunction显示文摘 | Pemberton OJ Johnson ML Ya ndle TQ et a I | 2001 | Clin Chim Acta2001，310，： | 1 |
| 17 | Overwhelming infection in a splenic patients:Current best practice preven-tive measures are not being followed显示文摘 | Wanhorn OJ | 2001 | JClin-Pathol2001，54，3： | 1 |
| 18 | Reduction of blood cholesterol in man显示文摘 | Pollak OJ | 1953 | Circulation1953，，7： | 1 |
| 19 | Bronchioloalveolar Carcinoma:Focal Area of Ground-Glass Attenuation at Thin-section CT as an Early Sign显示文摘 | Jang H J Lee KS Kwon OJ | 1996 | Radiology1996，199，2： | 1 |
| 20 | Immunity显示文摘 | Theze J Mccanee OJ Campion MJ | 1996 | Today1996，17，10： | 1 |
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