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| 1 | Clinical profile of diabetes at diagnosis among children and adolescents at an endocrine clinic in Ghana显示文摘AIM To determine the clinical features of diabetes in children and adolescents in Ghana.METHODS Retrospective review of clinical features of all children and adolescents with new-onset diabetes seen at the paediatric endocrinology clinic of Komfo Anokye Teaching Hospital in Kumasi, from February 2012 to Auguest 2016. RESULTS One hundred and six subjects presented with diabetes. Ninety(84.9%) were diagnosed by clinical features and family history as type 1, and 16(15.1%) type 2. For type 1 subjects, age range at diagnosis was 0.9-19.9 year(y), peak age of onset 12-13 year, and 3.3% were < 5 year, 21.1% 5-< 10 year, 45.6% 10-< 15 year and 30.0% 15-< 20 year. Seventy-one point one percent were female. Common clinical features were polyuria(100%), polydipsia(98.9%), and weight loss(82.2%). Mean BMI SD was -0.54, range -3.84 to 2.47. 60.0% presented in diabetic ketoacidosis(DKA). Nine had infections at onset(skin, abscess, leg ulcer). Mean± SD HbA 1c at diagnosis was 12.7% ± 1.9%(115±21 mmol/mol). Four have since died: Hypoglycaemia(2), recurrent DKA(1), osteosarcoma(1). Two other type 1 cases died of DKA at presentation in emergency before being seen by the paediatric endocrinologist. Crude mortality rate including these 2 cases was 32.2/1000 patient years. Type 2 cases were 81% female, age of onset 9-19 year. Mean BMI SD was 1.49, range -0.87 to 2.61. Forty-three point eight percent presented in DKA. All type 2 cases had acanthosis nigricans. Overall, 9.8% did not have home refrigeration, most using clay pot evaporative cooling for insulin storage. CONCLUSION Type 1 occurs with a female preponderance and high DKA rates. Type 2 also occurs. Typology based on clinical features is difficult. Community and professional awareness is warranted. | Emmanuel Ameyaw Serwah B Asafo-Agyei Sumithira Thavapalan Angela C Middlehurst Graham D Ogle | 2017 | World Journal of Diabetes2017,8,9: | 2 |
| 2 | The need for soeio - economic and environmental indicators to monitor degraded ecosystem rehabilitation: a ease study from Tanzania 显示文摘 | Ogle R B | 2001 | Agriculture Ecosystems & Environment2001,87,: | 1 |
| 3 | Growth performance, di- gestibility, gut environment and health status in weaned piglets fed a di- et supplemented with a complex of lactic acid bacteria alone or in com- bination with Bacillus subtilis and Saccharomyces boulardii显示文摘 | GIANG H H VIET T Q OGLE B | 2012 | Livest Sd2012,143,23: | 1 |
| 4 | Effect of enzyme treatment of piglet feeds on performance and post weaning diarrhoea 显示文摘 | INBORR J R OGLE B | 1988 | Swed Jour of Agri Res1988,18,: | 1 |
| 5 | Growth performance, digest- ibility, gut environment and health status in weaned piglets fed a diet supplemented with a complex of lactic acid bacteria alone or in com- bination with Bacillus subtilis and Saccharomyces boulardii 显示文摘 | GIANG H H VIET T Q OGLE B | 2012 | Li- vest Sci2012,143,23: | 1 |
| 6 | Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival显示文摘 | LIU X B WANG J A OGLE M E | 2009 | J Cell Biochem2009,106,5: | 1 |
| 7 | Obligatory running and gender: an analysis of participative motives and training habits显示文摘 | OGLES B M MASTERS K S RICHARDSON S A | 1995 | Intern J Sport Psychol1995,,26: | 1 |
| 8 | Psychological characteristicsof the obligatory runner:A critical examination of theanorexia analogue hypothesis显示文摘 | Coen S P Ogles B M | 1993 | Journal of Sport andExercise Psychology1993,15,3: | 1 |
| 9 | Growth per- formance, digestibility, gut environment and health sta- tus in weaned piglets fed a diet supplemented with po- tentially probiotics complexes of lactic acid bacteria 显示文摘 | GIANG H H VIET T Q OGLE B | 2010 | Livestock Science2010,129,: | 1 |
| 10 | Instability in slotted wall tunnels显示文摘 | King J L Doyle P Ogle J B | 1958 | Fluid Mech1958,14,: | 1 |
| 11 | Effects of supplementa- tion of probiotics on the performance, nutrient digestibility and faecal microflora in growing-finishing pigs显示文摘 | Giang H H Viet T Q Ogle B | 2011 | Asian-Austral- asian Journal of Animal Sciences2011,24,5: | 1 |
| 12 | Effect of scavenging and supplementation of lysine and methionine on the feed intake, performance and carcase quality of improved dual- purpose growing chickens显示文摘 | MINH D V OGLE B | 2005 | Tropical Animal Health and Production2005,37,7: | 1 |
| 13 | Growth per- formance, digestibility, gut environment and health sta- tus in weaned piglets fed a diet supplemented with a complex of lactic acid bacteria alone or in combination with Bacillus subtilis and Saccharomyces boulardii 显示文摘 | GIANG H H VIET T Q OGLE B | 2012 | Livestock Science2012,143,: | 1 |
| 14 | Biological implications of cell fusion显示文摘 | OGLE B M CASCALHO M PLATT J L | 2005 | Nature Renews Molecular Cell Biology2005,6,7: | 1 |
| 15 | Effects of different probiotic complexes of lactic acid bacteria on growth performance and gut environment of weaned piglets显示文摘 | GIANG H H VIET O T OGLE B | 2010 | Livestock Science2010,133,13: | 1 |
| 16 | Effects of supplementation of pro- biotics on the performance,nutlient and fecal micro flora in pigs显示文摘 | GIANG H H VIET T Q OGLE B | 2011 | Asi- an - australasian journal of animal sciences2011,24,5: | 1 |
| 17 | Effects of different probiotic complexes of lactic acid bacteria on growth performance and gut environment of weaned piglets显示文摘 | Giang HH Viet T Q Ogle B | 2010 | Livestock Science2010,133,: | 1 |
| 18 | Efficacy of bentonite clay in amelioratinga flatoxicosis in piglets fed aflatoxin contaminated diets显示文摘 | Nguyen Q T Ogle B Pettersson H | 2008 | Trop Anim Health Prod2008,40,: | 1 |
| 19 | Effect of enzyme treatment of piglet feeds on performance and post-weaning diarrhoea显示文摘 | Inborr J Ogle R B | | 0,,: | 1 |
| 20 | Hospice and primary care physicians:attitudes,knowledge and barriers显示文摘 | Ogle K Mavis B Wang T | | 0,,01: | 1 |