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| 1 | 利用厌氧颗粒污泥处理氯代有毒有机物显示文摘用能进行还原脱氯的微生物富集物接种,在小型试验装置内成功地培养出了具有还原脱氯功能的颗粒污泥。五氯苯酚能被这种颗粒污泥完全脱氯并进一步分解为甲烷和二氧化碳。四氯乙烯和其他氯代乙烯能被颗粒污泥还原脱氯为乙烯。这种脱氯的颗粒污泥可用来处理含有五氯苯酚和氯乙烯类的废水和地下水。 | 吴唯民 Nye,J | 1995 | 应用与环境生物学报1995，1，1： | 21 |
| 2 | The Future of American Power: Dominance and Decline in Perspective显示文摘 | Nye Joseph S | 2010 | Foreign Affairs2010，，6： | 3 |
| 3 | Thrombospondin peptide ABT-898 inhibits inflammation and angiogenesis in a colitis model显示文摘AIM: To evaluate the efficacy of the improvedthrombospondin mimetic peptide ABT-898 in a murine model of ulcerative colitis. METHODS: The dextran sodium sulfate(DSS) was used for the induction of colitis in both TSP-1 deficient(TSP-1-/-) and wild type(WT) mice during 7 d. While mice were receiving the DSS dissolved in the drinking water, the ABT-898 peptide was dissolved in sterile 5% glucose solution and delivered using mini pumps subcutaneously implanted. Plasma samples were analyzed for interleukin(IL)-6 by ELISA assay and colonic tissues were harvested, fixed and processed for histological evaluation. Immunohistochemistry using antibodies for the detection of CD31 and MECA in endothelial cells was performed. Inflammation was graded in colonic sections and the number of microvessels in each lesion was assessed. Activation of signal transducer and activator of transcription 3(STAT3) in colonic samples was quantified by immunohistochemistry and Western blotting using antibodies against total STAT3 and phosphorylated STAT3(p STAT3)(Ser727).RESULTS: Treatment with ABT-898 considerably diminished the inflammatory response in WT and TSP-1-/- mice(P < 0.0001 in both groups vs control). Identification of blood vessels highlighted by CD31/MECA immunohistochemistry, showed significantly reduced vessel counts in colitic lesions of WT and TSP-1-/- mice treated with ABT898(TSP-1-/- controls/TSP-1-/- treated, P = 0.0002; WT controls/WT treated, P = 0.0005). Consistently, IL-6 was significantly diminished in plasma samples of TSP-1-/- and WT treated with the peptide when compared to the control mice(P = 0.0002 and P = 0.0148, respectively). p STAT3 positive cells were quantified in WT and TSP-1-/- treated with ABT-898. A significant decrease in positive cells for p STAT3 was observed in treated mice(TSP-1-/- controls/TSP-1-/- treated, P = 0.0089; WT/WT treated, P = 0.0110). These results were confirmedby Western blotting analyses showing lower levels of p STAT3 in colitic lesions from mice treated with the peptide ABT-898.CONCLUSION: These findings indicate that the new peptide ABT-898 ameliorates inflammation and angiogenesis and might be a therapeutic alternative in IBD and inflammatory diseases. | Linda S Gutierrez Jun Ling Derek Nye Konstantina Papathomas Catherine Dickinson | 2015 | World Journal of Gastroenterology2015，21，20： | 2 |
| 4 | Diffusion of phosphate to plant roots in soil显示文摘 | K. K. S. Bhat P. H. Nye | 1974 | Plant and Soil1974，，2： | 2 |
| 5 | Diffusion of phosphate to plant roots in soil显示文摘 | K. K. S. Bhat P. H. Nye | 1973 | Plant and Soil1973，，1： | 2 |
| 6 | Statin therapy is associated with lower mortality among patients with severe heart failure显示文摘 | Mozaffarian D Nye R Levy WC | 2004 | Am J Cardiol2004，93，： | 1 |
| 7 | Anaerobic dechlorination of trichloroethylene (TCE) to ethylene using complex organic materials显示文摘 | Wu W Nye J Hickey R F | 1998 | Water Res1998，32，5： | 1 |
| 8 | Rainbows from Ellipsoidal Water Drops显示文摘 | Nye J F | 1992 | Proceedings:Mathematical and Physical Sciences1992，438，1903： | 1 |
| 9 | The Challenge of Soft Power 显示文摘 | Joseph Nye | 1999 | Time Magazine Febary 221999，，： | 1 |
| 10 | America ' s Information Edge显示文摘 | Nye Owens | 1996 | For- eign Affairs1996，，34： | 1 |
| 11 | Statin therapy is associated with lower mortality among patients with severe heart failure显示文摘 | Mozaffrian D Nye R Levy W | 2004 | Am Cardid2004，93，9： | 1 |
| 12 | Mammalian neurotro- phin-4: structure, chromosomal localization, tissue distribu- tion, and receptor specificity 显示文摘 | Ip N Y Ibanez C F Nye S H | 1992 | PNAS1992，89，： | 1 |
| 13 | Large-scale chromatin structure and function显示文摘 | Dietzel S Nye AC | 1999 | Curr Opin Cell Biol1999，11，3： | 1 |
| 14 | A technique to evaluate an internal spinal device by use of the Selspot system:An application to Luque closed loop显示文摘 | Goel VK Nye TA Clark CR | 1987 | Spine1987，12，： | 1 |
| 15 | Soft Power显示文摘 | Nye J S | 1990 | Foreign Policy1990，，80： | 1 |
| 16 | The Challenge of Soft Power显示文摘 | Josephs Nye | 1999 | Time1999，，： | 1 |
| 17 | Conflicts After the Cold War 显示文摘 | Joseph Nye | 1996 | The Washington Quarterly(volume 19)1996，，： | 1 |
| 18 | Statin therapy is associated with lower mortality among patients with severe heart failure 显示文摘 | Mozaffarian D Nye R Levy WC | 2004 | Am J Cardiol2004，93，9： | 1 |
| 19 | Soft Power显示文摘 | Nye J.S Jr | | 0，，： | 1 |
| 20 | Alzheimer’s disease research and development: a call for a new research roadmap显示文摘 | Howard H. Feldman Magali Haas Sam Gandy Darryle D. Schoepp Alan J. Cross Richard Mayeux Reisa A. Sperling Howard Fillit Diana L. Hoef Sonya Dougal Jeffrey S. Nye | 2014 | Ann NY Acad Sci2014，，1： | 1 |
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