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| 1 | Search for the QCD critical point with fluctuations of conserved quantities in relativistic heavy-ion collisions at RHIC: an overview显示文摘Fluctuations of conserved quantities, such as baryon, electric charge, and strangeness number, are sensitive observables in relativistic heavy-ion collisions to probe the QCD phase transition and search for the QCD critical point. In this paper, we review the experimental measurements of the cumulants(up to fourth order) of event-byevent net-proton(proxy for net-baryon), net-charge and netkaon(proxy for net-strangeness) multiplicity distributions Au+Au collisions at sNN^(1/2) 7:7; 11:5; 14:5; 19:6; 27;39; 62:4; 200 Ge V from the first phase of beam energy scan program at the relativistic heavy-ion collider(RHIC). We also summarize the data analysis methods of suppressing the volume fluctuations, auto-correlations, and the unified description of efficiency correction and error estimation.Based on theoretical and model calculations, we will discuss the characteristic signatures of critical point as well as backgrounds for the fluctuation observables in heavy-ion collisions. The physics implications and the future secondphase of the beam energy scan(2019–2020) at RHIC will also be discussed. | Xiaofeng Luo Nu XU | 2017 | Nuclear Science and Techniques2017，28，8： | 19 |
| 2 | Circular RNAs and human glioma显示文摘As a newly discovered type of RNA, circular RNAs(circRNAs) are widespread throughout the eukaryotic genome. The expression of circRNAs is regulated by both cis-elements and trans-factors, and the expression pattern of circRNAs is cell type-and diseasespecific. Similar to other types of non-coding RNAs, functions of circRNAs are also versatile. CircRNAs have been reported previously to function as microRNA(miRNA) sponges, protein sponges, coding RNAs or scaffolds for protein complexes.Recently, several circRNAs have been reported to play important roles in human malignancies, including glioma. Here, we reviewed several reports related to circRNAs and glioma, as well as the potential diagnostic and therapeutic applications of circRNAs in brain cancer. In general, some circRNAs, such as circSMARCA5 and circCFH, are found to be expressed in a gliomaspecific pattern, these circRNAs may be used as tumor biomarkers. In addition, some circRNAs have been found to play oncogenic roles in glioma(e.g., circNFIX and circNT5E), whereas others have been reported to function as tumor suppressors(e.g.,circFBXW7 and circSHPRH). Furthermore, circRNA is a good tool for protein expression because of its higher stability compared to linear RNAs. Thus, circRNAs may also be an ideal choice for gene/protein delivery in future brain cancer therapies. There are some challenges in circRNA research in glioma and other diseases. Research related to circRNAs in glioma is comparatively new and many mysteries remain to be solved. | Jinglei Liu Kun Zhao Nunu Huang Nu Zhang | 2019 | Cancer Biology & Medicine2019，16，1： | 16 |
| 3 | 分泌型乳腺癌的临床病理特征显示文摘目的:探讨乳腺分泌型癌的临床病理特征、诊断和鉴别诊断要点。方法:分析14例分泌型乳腺癌患者的临床病理资料,进行光镜观察,部分病例进行组织化学及免疫组化染色,并复习文献。结果:分泌型乳腺癌临床及病理大体观察与其他类型乳腺癌无明显区别,主要表现为乳房内肿块,多位于乳晕区,大体观察肿物大多边界不清、质地硬,光镜下肿瘤细胞主要排列成实性、小囊性和导管性三种结构,瘤细胞有颗粒性嗜酸性胞质,瘤细胞内外有大量均质嗜伊红PAS阳性分泌物。腋下淋巴结转移较少(2/14)。无局部复发或远处转移(随访3~14年)。结论:分泌型乳腺癌为罕见且预后较好的乳腺癌,确诊必须依靠病理检查。 | 郎荣刚 Nu Yun 牛昀 范宇 | 2001 | 临床与实验病理学杂志2001，17，1： | 9 |
| 4 | Portal hypertensive colopathy is associated with portal hypertension severity in cirrhotic patients显示文摘AIM:To assess the prevalence of portal hypertension (PH) related colorectal lesions in liver transplant candidates, and to evaluate its association with the severity of PH.METHODS: Between October 2004 and December 2005, colonoscopy was performed in 92 cirrhotic liver transplant candidates. We described the lesions resulting from colorectal PH and their association with the grade of PH in 77 patients who underwent measurement of hepatic venous pressure gradient (HVPG).RESULTS: Mean age was 55 years and 80.7% of patients were men. The main etiology of cirrhosis was alcoholism (45.5%). Portal hypertensive colopathy (PHC) was found in 23.9%, colonic varices in 7.6% and polyps in 38% of patients (adenomatous type 65.2%). One asymptomatic patient had a well-differentiated adenocarcinoma. The manifestations of colorectal PH were not associated with the etiology of liver disease or with the Child-Pugh grade. Ninety percent of patients with colopathy presented with gastroesopha-geal varices (GEV), and 27.5% of patients with GEV presented with colopathy (P=0.12). A relationship between higher values of HVPG and presence of col-opathy was observed (19.9±6.2 mmHg vs 16.8±5.4 mmHg, P=0.045), but not with the grade of col-opathy (P=0.13). Preneoplastic polyps and neoplasm (P=0.02) and spontaneous bacterial peritonitis (P=0.006) were more prevalent in patients with colopathy. We did not observe any association between previous β-blocker therapy and the presence of colorectal portal hypertensive vasculopathy.CONCLUSION: PHC is common in cirrhotic liver trans-plant candidates and is associated with higher portal pressure. | Antonio Diaz-Sanchez Oscar Nuez-Martinez Cecilia Gonzalez-Asanza Ana Matilla Beatriz Merino Diego Rincon Inmaculada Beceiro Maria Vega Catalina Magdalena Salcedo Rafael Baares Gerardo Clemente | 2009 | World Journal of Gastroenterology2009，15，38： | 6 |
| 5 | Simulation study on cavity growth in ductile metal materials under dynamic loading显示文摘 | Ai-Guo Nu Guang-Cai Zhang Yang-Jun Ying Xi-Jun Yu | 2013 | Frontiers of physics2013，8，4： | 5 |
| 6 | Trephination mini-craniectomy for traumatic posterior fossa epidural hematomas in selected pediatric patients显示文摘以后的窝硬膜上的 hematomas (PFEDH ) 在孩子是不平常的,但是通常由于威胁生活的 brainstem 压缩的风险要求及时外科的干预。我们试图由与回顾地考察的 trephination mini-craniectomy.MethodsWe 对待选择小儿科的病人使外科的过程更少侵略从2010年1月为创伤的 PFEDH 在我们的部门被对待到2015年1月 .ResultsDuring 的小儿科的病人的临床的功课,放射学的调查结果,外科的过程,和预测这个时期, 17 个病人的一个总数通过手术为 PFEDH 被对待, 7 为 hemato 与 trephination 微型部分颅骨切除术被管理结果在与格拉斯哥结果 20 评估了的所有 7 个病人好。在这个系列没有死亡。平均 30 月的临床的后续证明没有 complications.ConclusionOur 结果,病人们经历了令人满意的恢复建议 trephination 微型部分颅骨切除术是为有中等 hematoma 的选择 PFEDH 病人的一种安全外科的技术体积和稳定的神经病学的功能。然而,标准部分颅骨切除术是当在神经病学的功能或 hematomas 是的病人有快速的恶化时,推荐大、施加的严重集体效果。 | Han-Song Sheng Chao-Guo You Liang Yang Nu Zhang Jian Lin Fen-Chun Lin Mao-De Wang | 2017 | Chinese Journal of Traumatology2017，20，4： | 5 |
| 7 | Adaptive contourlet-wavelet iterative shrinkage/thresholding for remote sensing image restoration显示文摘In this paper, we present an adaptive two-step contourlet-wavelet iterative shrinkage/thresholding(TcwIST) algorithm for remote sensing image restoration. This algorithm can be used to deal with various linear inverse problems(LIPs), including image deconvolution and reconstruction. This algorithm is a new version of the famous two-step iterative shrinkage/thresholding(TwIST) algorithm. First, we use the split Bregman Rudin-Osher-Fatemi(ROF) model, based on a sparse dictionary, to decompose the image into cartoon and texture parts, which are represented by wavelet and contourlet, respectively. Second, we use an adaptive method to estimate the regularization parameter and the shrinkage threshold. Finally, we use a linear search method to find a step length and a fast method to accelerate convergence. Results show that our method can achieve a signal-to-noise ratio improvement(ISNR) for image restoration and high convergence speed. | Nu WEN Shi-zhi YANG Cheng-jie ZHU Sheng-cheng CUI | 2014 | Journal of Zhejiang University-Science C(Computers and Electronics)2014，15，8： | 5 |
| 8 | Gallstone ileus:One-stage surgery in a patient with intermittent obstruction显示文摘Gallstone ileus, an uncommon complication of cholelithiasis, is described as a mechanical intestinal obstruction due to impaction of one or more large gallstones within the gastrointestinal tract. The clinical presentation is variable, depending on the site of obstruction, manifested as acute, intermittent or chronic episodes. A 51-year-old female patient was referred to our hospital with 3 events of intestinal obstruction during the previous 7 d. At admission, there were clinical signs of intestinal obstruction; abdominal film demonstrated dilated bowel loops, air-fluid levels and a vague image of a stone in the inferior left quadrant. Once stabilized, a laparotomy was performed. Surgical findings were distention of the jejunum and ileum proximal to a palpable stone in the ileum as well as gallstones and a cholecystoduodenal fistula in the gallbladder. An enterolithotomy, repair of the cholecystoduodenal fistula and cholecystectomy were performed. The postoperative course was uneventful. There is no uniform surgical procedure for this disease. When the patient is too ill or when biliary surgery is not advisable, an enterolithotomy is the best option. The one-stage procedure should be the offered to adequately stabilized patients when local and general conditions, such as good cardiorespiratory and metabolic reserve permit a more prolonged surgical procedure. | Carlos M Nuo-Guzmán José Arróniz-Jáuregui Pável A Moreno-Pérez édgar A Chávez-Solís Nereida Esparza-Arias Cuauhtémoc I Hernández-González | 2010 | World Journal of Gastrointestinal Surgery2010，2，5： | 5 |
| 9 | Conceptual design of the HIRFL-CSR external-target experiment显示文摘One of the main purposes of heavy-ion collisions over a wide range of beam energy is to study the bulk properties of strong interaction matter and understand the Quantum Chromo Dynamics(QCD)phase diagram,which carries wealth of information of the phase transition and the possibly existing critical point of the strongly interacting system[1].Such system exists as hadron gases at lower temperature and low baryon density.By increasing the temperature or density,the boundary of the hadrons disappears and the confined quarks | LiMing Lu Hart Yi ZhiGang Xiao Ming Shao Song Zhang GuoQing Xiao Nu Xu | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，1： | 3 |
| 10 | 在培养基和食料中添加铅和镉对轮虫种群动态的影响(英文)显示文摘由于工业活动的影响 ,墨西哥水体环境中的重金属浓度在上升。浮游动物 ,尤其是轮虫类 ,由于对环境变化十分敏感而且是淡水中的常见组成部分 ,因此被广泛用于生态毒理试验以确定水质标准。在不同的胁迫途径下 (如通过培养基或食料 ) ,重金属的毒性是不同的。在本研究中 ,通过在轮虫Brachionusrubens的培养基和食料中添加重金属这两种途径 ,我们评估了镉和铅的效应。对于这两种重金属 ,均采用将轮虫置于含 0 5×10 6个 /ml绿藻的培养基中或每天喂食经 5倍于LC50 值的金属处理 (1,2和 4h)的绿藻。对于在培养基中添加镉 ,使用了三个毒性水平 (0 1,0 2和 0 4mg/L) ,铅的浓度分别为 0 0 0 5 ,0 0 10和 0 0 15mg/L。基于LC50的数据 ,B .rubens对铅的敏感性要比镉高 2 4倍。镉浓度为 0 4mg/L时 ,培养基中加入镉造成B .rubens的生长趋缓。而喂食经不同时间处理的绿藻后 ,轮虫的密度随着食料在重金属中处理时间的延长而减小。培养基中或食料中添加铅时 ,轮虫种群生长的的趋势与在镉处理下的情况类似。随着培养基中重金属浓度的增加 ,每天种群增长率 (r值 )会减小。在培养基和食料处理两种不同途径下 ,r值会在 0 33(对照 )到 0 0 2d-1(经重金属处理 ) | S.S.S.SARMA Hilda Fabiola NU'EZ-CRUZ S. NANDINI | 2005 | 动物学报2005，51，1： | 3 |
| 11 | Successful treatment of pyogenic ventriculitis caused by extensively drug-resistant Acinetobacter baumannii with multi-route tigecycline: A case report显示文摘BACKGROUND Pyogenic ventriculitis caused by extensively drug-resistant Acinetobacter baumannii(A.baumannii)is one of the most severe complications associated with craniotomy.However,limited therapeutic options exist for the treatment of A.baumannii ventriculitis due to the poor penetration rate of most antibiotics through the blood-brain barrier.CASE SUMMARY A 68-year-old male patient with severe traumatic brain injury developed pyogenic ventriculitis on postoperative day 24 caused by extensively drug-resistant A.baumannii susceptible to tigecycline only.Successful treatment was accomplished through multi-route administration of tigecycline,including intravenous combined with continuous ventricular irrigation plus intraventricular administration.The pus was cleared on the 3rd day post-irrigation,and cerebrospinal fluid cultures were negative after 12 d.CONCLUSION Our findings suggest that multi-route administration of tigecycline can be a therapeutic option against pyogenic ventriculitis caused by extensively drugresistant A.baumannii. | Wei Li Dan-Dong Li Bo Yin Dong-Dong Lin Han-Song Sheng Nu Zhang | 2021 | World Journal of Clinical Cases2021，9，3： | 2 |
| 12 | Serum tumor markers CEA,CYFRA21-1,and CA-125 are associated with worse prognosis in advanced non-small-cell lung cancer (NSCLC)显示文摘 | Cedrés S Nu?ez I Longo M | | 0，，03： | 2 |
| 13 | The black pottery coating of longshan times from Taosi Site显示文摘Taosi is an archaeological site in Xiangfen county, Shanxi province. It is considered as a capital city site with the rudiment of an early country in Longshan Times. In this work, the black pottery coating was found on the surface of black and grey pottery of Longshan times and confirmed by scientific studies for the first time. It filled in the blank of pottery coating study in this time period at the Yellow River Valley, as well as supplied a new study method of 'black skin pottery' besides the carburization craft. In addition, according to the archaeological materials, we inferred that the wares with this pottery coating might be only used by the nobility at that time. | LU XiaoKe LI WeiDong LUO HongJie HE Nu LI XinWei | 2011 | Science China(Technological Sciences)2011，54，7： | 2 |
| 14 | Forage biomass of 22 shrub species from Monfragüe Natural Park (SW Spain) assessed by log–log regression models显示文摘 | D. Paton J. Nu?ez D. Bao A. Mu?oz | 2002 | Journal of Arid Environments2002，，2： | 2 |
| 15 | 航空器巡航阶段空气污染的排放和扩散显示文摘为了探索航空器巡航阶段的排放和扩散,假设航空器巡航阶段推力为其最大推力的70%,以国际民航组织发动机排放数据库中的GEnx-2B67/P发动机氮氧化物(NO x)的排放为例,利用全空域航空排放评估系统(SAGE)进行数值仿真,计算得到飞行方向上的排放强度。然后假设飞行方向为恒定的线源排放方向,且与风向垂直,基于高斯扩散模型,得到航空器巡航阶段的污染扩散模型。最后采取ICAO在2012年美国俄亥俄州Peebles数据,对NO x浓度扩散进行数值仿真,成功计算出当时当地GEnx-2B67/P发动机在巡航状态下飞机排放的NO x浓度分布情况。仿真结果表明随着航空器距线源高度的增加,NO x浓度分布符合高斯分布的性质,且在不同高度上NO x浓度都是先急剧增大到峰值后缓慢减少。 | YU Nu 张梦雅 张耀 田勇 曾若鸣 | 2020 | 科学技术与工程2020，20，34： | 2 |
| 16 | Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers显示文摘瞄准:分析在肝的 anti-HBs 的存在是否移植接受者在阻止 HBV 感染是有效的。方法:23 个病人收到 anti-HBc 积极的肝被学习。九个接受者是由于以前的 HBV 感染积极的 anti-HBc。他们,一个人也收到了在肝前移植时期期间疫苗的 HBV。十四个接受者是由于在预先移植经期期间管理的 HBV 疫苗积极的 anti-HBs。肝活体检视在 10/14 anti-HBc negative/anti-HBs 被获得积极接受者并且在 4/9 anti-HBc 积极接受者。结果:在 46 个月的一个吝啬的后续时期以后,有保护的浆液 anti-HBs 层次的 1 个接受者作为有免疫力的逃跑 HBV 异种的后果得了 de novo HBV 感染。在 14 之中种牛痘的 anti-HBc negative/anti-HBs 积极接受者,有可得到的肝活体检视(10%) 的 1/10 病人在 13 瞬间有肝 HBV-DNA 没有浆液的肝以后的移植病毒的标记并且没得 de novo HBV 感染。种牛痘的 anti-HBc 没有 HBV 疫苗的反应的积极接受者是在浆液和肝积极的 HBV-DNA,病毒的 DNA 在下列测试是连续地否定的,自发的 seroconversion 因此被诊断。结论:由于 HBV 疫苗或过去的 HBV 感染的 anti-HBs 的存在似乎在保护从 anti-HBc 收到肝的病人有效积极施主。然而,有免疫力的逃跑 HBV 异种的出现,能躲避 anti-HBs 保护,应该被看作 HBV 感染的风险。 | Rafael Barcena Gloria Moraleda Javier Moreno M Dolores Martín Emilio de Vicente Jesús Nuo M Luisa Mateos Santos del Campo | 2006 | World Journal of Gastroenterology2006，12，13： | 2 |
| 17 | Vascular endothehal growth factor receptor-1 mediates migration of human colorectal carcinoma ceils by activation of Src family kinases 显示文摘 | Lesslie DP Summy JM Parikh NU | 2006 | Br J Cancer2006，94，11： | 1 |
| 18 | An update on cardioembolic stroke 显示文摘 | Weir NU | 2008 | Postgrad Med J2008，84，： | 1 |
| 19 | Combined inhibition of IGF-IR/IR and Src family kinases enhances antitumor effects in prostate cancer by decreasing activated survival pathways显示文摘 | Dayyani F Parikh NU Varkaris AS | | 0，，12： | 1 |
| 20 | Monte Carlo simulation of stellar intensity interferometry显示文摘 | Rou J Nu N Ez P D Kieda D | 2013 | Monthly Notices of the Royal Astronomieal Society2013，430，4： | 1 |
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