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您的检索式：作者名="Norman CDuke"
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| 1 | Convergent adaptation of the genomes of woody plants at the land-sea interface显示文摘Sequencing multiple species that share the same ecological niche may be a new frontier for genomic studies.While such studies should shed light on molecular convergence,genomic-level analyses have been unsuccessful,due mainly to the absence of empirical controls.Woody plant species that colonized the global tropical coasts,collectively referred to as mangroves,are ideal for convergence studies.Here,we sequenced the genomes/transcriptomes of 16 species belonging in three major mangrove clades.To detect convergence in a large phylogeny,a CCS+model is implemented,extending the more limited CCS method(convergence at conservative sites).Using the empirical control for reference,the CCS+model reduces the noises drastically,thus permitting the identification of 73 convergent genes with Ptrue(probability of true convergence)>0.9.Products of the convergent genes tend to be on the plasma membrane associated with salinity tolerance.Importantly,convergence is more often manifested at a higher level than at amino-acid(AA)sites.Relative to>50 plant species,mangroves strongly prefer 4 AAs and avoid 5 others across the genome.AA substitutions between mangrove species strongly reflect these tendencies.In conclusion,the selection of taxa,the number of species and,in particular,the empirical control are all crucial for detecting genome-wide convergence.We believe this large study of mangroves is the first successful attempt at detecting genome-wide site convergence. | Ziwen He Shaohua Xu Zhang Zhang Wuxia Guo Haomin Lyu Cairong Zhong David EBoufford Norman CDuke The International Mangrove Consortium Suhua Shi | 2020 | National Science Review2020，7，6： | 3 |
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