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| 1 | Current status and prospects of clinical proteomics studies on detection of colorectal cancer:Hopes and fears显示文摘Colorectal adenocarcinoma (CRC) is the third most com-mon type of cancer and the fourth most frequent cause of death due to cancer worldwide. Given the natural history of CRC, early diagnosis appears to be the most appropriate tool to reduce disease-related mortality. A fi eld of recent interest is clinical proteomics, which was reported to lead to high sensitivity and specifi cities for early detection of several solid tumors. This emerging fi eld uses mass spectrometry-based protein profi les/pat-terns of easy accessible body fluids to distinguish cancer from non-cancer patients. These discrepancies may be a result of: (1) proteins being abnormally produced or shed and added to the serum proteome, (2) proteins clipped or modified as a consequence of the disease process, or (3) proteins subtracted from the proteome owing to disease-related proteolytic degradation path-ways. Therefore, protein pattern diagnostics would pro-vide easy and reliable tools for detection of cancer. This paper focuses on the current status of clinical proteomics research in oncology and in colorectal cancer especially, and will re? ect on pitfalls and fears in this relatively new area of clinical medicine, which are reproducibility issues and pre-analytical factors, statistical issues, and identifi -cation and nature of discriminating proteins/peptides. | ME de Noo RAEM Tollenaar AM Deelder LH Bouwman | 2006 | World Journal of Gastroenterology2006，12，41： | 3 |
| 2 | Effects of traditional Chinese herbal medicine San-HuangXie-Xin-Tang on gastrointestinal motility in mice显示文摘AIM: To investigate the effects of San-Huang-Xie-XinTang(SHXXT), a herbal product used in traditional Chinese medicine, on gastrointestinal(GI) motility in mice.METHODS: The in vivo effects of SHXXT on GI motility were investigated by measuring the intestinal transit rates(ITRs) using Evans blue in normal mice and in mice with experimentally induced GI motility dysfunction(GMD).RESULTS: In normal ICR mice, ITRs were significantly and dose-dependently increased by SHXXT(0.1-1 g/kg). GMD was induced by injecting acetic acid or streptozotocin intraperitoneally. The ITRs of GMD mice were significantly reduced compared to normal mice, and these reductions were significantly and dose-dependently inhibited by SHXXT(0.1-1 g/kg).CONCLUSION: These results suggest that SHXXT is a novel candidate for the development of a prokinetic agent that may prevent or alleviate GMD. | Min Woo Hwang Tae Seok Ahn Noo Ri Hong Han-Sol Jeong Myeong Ho Jung Ki-Tae Ha Byung Joo Kim | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 3 | Truncated Hilbert transform and image reconstruction from limited tomographic data 显示文摘 | DEFRISE M NOO F CLACKDOYLE R KUDO H | 2006 | Inverse Problems2006，22，3： | 1 |
| 4 | A quantitative reconstruction from truncated projections in classical tomography 显示文摘 | Clackdoyle R Noo F Guo Junyu | 2004 | IEEE Trans Nucl Sci2004，51，3： | 1 |
| 5 | Exact helical reconstruction using native cone-beam geometries显示文摘 | Noo F Pack J Heuscher D | 2003 | Physics in Medicine and Biology2003，48，： | 1 |
| 6 | Assessing environmental impacts of municipal solid waste of johor by analytical hierarchy process显示文摘 | Abba Ahmad Halilu Noo Zainura Zainon Yusuf Rafiu O | 2013 | Resources con- servation and recycling2013，73，： | 1 |
| 7 | A large class of inversion formula for the 2D Radon transform of functions of compact support 显示文摘 | Clackdoyle R Noo F | 2004 | Inverse Problems2004，20，4： | 1 |
| 8 | Analytic method based on identification of ellipse parameters for scanner calibration in cone-beam tomography显示文摘 | Noo F Clackdoyle R Mennessier C | 2000 | Physics in Medicine and Biology2000，45，11： | 1 |
| 9 | Cone-beam reconstruction using 1D filtering along the projection of M-lines显示文摘 | Pack JD Noo F | 2005 | Inverse Problem2005，21，： | 1 |
| 10 | Cone-beam reconstruction using the bockprojection of locally filtered projections显示文摘 | Pack JD Noo F Clack R | 2005 | IEEE Trans Med Imag2005，24，1： | 1 |
| 11 | Wavelet based approach for structural damage detection 显示文摘 | Hou Z Noo ri M Amand R St | 2000 | Journal of Engineering Mechanics ASCE2000，126，7： | 1 |
| 12 | Solving the generalized Burgers-Huxley equation using the Adomian decomposition method 显示文摘 | HA I NOO M S M SAID M R | 2006 | Math Compu Mod2006，43，1112： | 1 |
| 13 | Quasiexact filtered backprojection algorithm for long-object problem in helical cone-beam tomography显示文摘 | Hiroyuki Kudo Frederic Noo Michel Defrise | 2000 | IEEE Trans Medlmag2000，19，90： | 1 |
| 14 | Analyticmethod based on identification of ellipse parametersfor scanner calibration in cone-beam tomography 显示文摘 | Noo F Clackdoyle R Mennessier C | 2000 | Physics in Medicine and Biology2000，45，11： | 1 |
| 15 | Tiny a prior knowledge solves the interior problem in compu- terd tomography 显示文摘 | KUDO H COURDURIER M NOO F DEFRISE M | 2008 | Physics in Medicine and Biology2008，53，7： | 1 |
| 16 | Fan-beam filtered- backprojection reconstruction without backprojection weight 显示文摘 | Dennerlein F Noo F Homegger J | 2007 | Physics in Medicine and Biology2007，52，： | 1 |
| 17 | Exact helical reconstruction us- ing native cone-beam geometries显示文摘 | NOO F PACK J HFUSCHER D | 2003 | Physics in Medicine and Biolo- gy2003，48，23： | 1 |
| 18 | Image reconstruction from fan-beam projections on less than a half scan 显示文摘 | Noo F Defrise M Clackdoyle R | 2002 | Phys Med Biol2002，47，： | 1 |
| 19 | Cone-beam filtered-backprojection algorithm for truncated data 显示文摘 | H Kudo F Noo and M Defrise | 1993 | Physics in Medicine and Biology1993，43，： | 1 |
| 20 | Exact helical reconstruction using na-tive cone-beam geometries显示文摘 | Noo F Pack J Heuseher D | 2003 | Phys Med Biol2003，48，： | 1 |
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