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| 1 | 气团来源对瓦里关地区颗粒物数谱分布的影响显示文摘通过对2005年8月到2007年5月在瓦里关全球本底站观测的气溶胶数谱分布资料和同期后向轨迹资料分析,发现气团来源对瓦里关地区颗粒物的数浓度及其谱分布有显著影响.气团起源于瓦里关东北部地区或者途径东北部地区,传输路径较短,传输速度相对较慢,大气中出现较高数浓度的爱根核模态颗粒物;气团来源于瓦里关西部或者西北地区时,传输路径较长,传输速度较快,大气中一般出现较高浓度的核模态颗粒物. | 占明锦 孙俊英 张养梅 张晓春 乜虹 德力格尔 Niku Kivekas Heikki Lihavainen | 2009 | 冰川冻土2009，31，4： | 12 |
| 2 | Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma显示文摘BACKGROUND Overexpression of heat shock proteins(HSPs) is associated with several malignancies and contributes to the development, progression, and metastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several malignancies. Due to the poor prognosis of esophageal adenocarcinoma(EAC), it would be valuable to find new biomarkers for the development of cancer treatments.AIM To evaluate the expressions of HSP27 and HSP70 and their effect on survival in EAC.METHODS Immunohistochemical analyses and evaluations of HSP27 and HSP70 expression were performed on all available samples from 93 patients diagnosed with EACbetween 1990 and 2007 at two university hospitals. Fifteen cases with Barrett's metaplasia and 5 control cases from the same patient population were included in the analysis. HSP expression was quantitatively assessed and classified as high or low. Kaplan-Meier analyses and Cox regression models adjusting for age and sex as well as tumor site, stage, and grade were used to evaluate the effect on survival.RESULTS Tumor stage and surgical treatment were the main prognostic factors. High HSP27 expression in cancer cases was a strong negative predictive factor, with a mean survival of 23 mo compared to the 49 mo in cases with a low expression(P= 0.018). The results were similar for HSP70, with a poorer survival of 17 mo in cases with high HSP70 expression, in contrast to 40 mo(P = 0.006) in cases with a low expression. A Cox regression survival analysis was performed, adjusting for possible confounding factors, and higher HSP27 and HSP70 expressions remained an independent negative prognostic factor. The HSPs' correlation with survival was not affected by cancer treatments. When the analysis was adjusted for all factors, the odds ratios for HSP27 and HSP70 were 3.3(CI: 1.6–6.6, P =0.001) and 2.2(CI: 1.2–3.9, P = 0.02), respectively.CONCLUSION HSP27 and HSP70 overexpression is associated with poor survival in EAC, which is, to the best of our knowledge, reported for the first time. | Henna K S?derstr?m Juha T Kauppi Niku Oksala Timo Paavonen Leena Krogerus Jari R?s?nen Tuomo Rantanen | 2019 | World Journal of Clinical Cases2019，7，3： | 7 |
| 3 | Performance of activated sludge process and reliability-based design 显示文摘 | Niku S Schroeder E D Samaniego F J | 1979 | Journal of Water Pollution Control Federation1979，51，12： | 1 |
| 4 | PR depression is useful in the differential diagnosis of myopericarditis and ST elevation myocardial infarction显示文摘 | Porela P Kyto V Nikus K | | 0，，02： | 1 |
| 5 | Predicting the culpritartery in acute ST-elevation myocardial infarction and introducing a new algorithm to predict infarct-related artery in inferior ST-elevation myocardial infarction: correlation with coronary anatomy in the HAAMU Trial显示文摘 | Tierala I Nikus KC Sclarovsky S | 2009 | J Electrocardiol2009，42，2： | 1 |
| 6 | Lymphangioleiomyomatosis:clinical,pathologic,and radiologicm anifestations显示文摘 | Niku S Stark P Levin DL | 2005 | J Thorac Imaging2005，20，2： | 1 |
| 7 | Introduction to Robotics: Analysis, Systems, Application 显示文摘 | Saeed B Niku | 2001 | USA: Pearson Education2001，，： | 1 |
| 8 | Lymphangioleiomyomatosis:clinical,pathologic,and radiologic manifestations显示文摘 | Niku S Stark P Levin DL | | 0，，： | 1 |
| 9 | Metabolite fi ndings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy显示文摘 | Cianfoni A Niku S Imbesi SG | 2007 | AJNR2007，28，： | 1 |
| 10 | Acute respiratory failure dur- ng routine blood transfusion : a case report and review of the litera- ture 显示文摘 | Torbati SS Schlesinger S Niku D | 2014 | J Emerg Med2014，46，3： | 1 |
| 11 | Electrocardiogram patterns in acute left main coronary artery occlusion显示文摘 | Nikus KC Eskola MJ | 2008 | J Electrocardiol2008，41，6： | 1 |
| 12 | A novel combination of prosthetic groups in a fungal laccase ; PQQ and two copper atoms 显示文摘 | KARHUNEN E NIKU -PAAVOLA M L VIIKARI L | 1990 | FEBS Lett1990，267，1： | 1 |
| 13 | Metabolite findings in tume- factive demyelinating lesions utilizing short echo time pro- ton magnctic resonance spectroscopy 显示文摘 | Cianfoni A Niku S Imbesi SG | 2007 | Am J Neuroradiol2007，28，2： | 1 |
| 14 | Manifestation of left main coronary artery stenosis is diffuse ST depression in inferior and precordial leads on ECG显示文摘 | Sclarovsky S Nikus KC Brinbaum Y | 2002 | J Am Coll Cardiol2002，40，3： | 1 |
| 15 | Detection of white-rot fungi by non-toxic stain 显示文摘 | Niku P Raaskam I | 1990 | Mycology Res1990，94，： | 1 |
| 16 | Lymphangioleiomyomatosis : clini cal,pathologic, and radiologic manifestations显示文摘 | Niku S Stark P Levin DL | 2005 | J Thorac Imaging2005，20，2： | 1 |
| 17 | PR depression is useful in the differential diagnosis of myopericarditis and ST elevaticm myocardial infarction 显示文摘 | Porela P Kyte V Nikus K | 2012 | Ann Noninvasive Electrocardioi2012，17，2： | 1 |
| 18 | Predicting the culprit artery in acute ST-elevation myocardial infarotion and introducing a new algorithm to predict infarct-related artery in inferior ST-elevation myocardial infarction:correlation with coronary anatomy in the HAAMU Trial显示文摘 | Tierala I Nikus KC Sclarovsky S | | 0，，02： | 1 |
| 19 | Lymphangioloeiomymatosis: clin ical,pathologygic,and Radiologic manifestations显示文摘 | NikuS StarkP LevinD L etal | 2005 | J Thorac imaging2005，20，2： | 1 |
| 20 | Metabolite findings in tumefac-tive demyelinating lesions utilizing short echo time proton mag- netic resonance spectroscopy 显示文摘 | Cianfoni A Niku S Imbesi SG | 2007 | AJNR Am J Neuroradiol2007，28，2： | 1 |
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