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| 1 | 单髁与全膝关节置换治疗内侧间室膝骨关节炎:5年假体在位率比较显示文摘背景:单髁置换越来越多的被应用于治疗单纯内侧胫股间室型膝关节骨关节炎。目的:比较膝关节单髁置换与全膝关节置换对膝关节单纯内侧间室骨关节炎的修复效果。方法:纳入单纯内侧间室型膝关节骨关节炎患者109例,根据修复方式分为两组,单髁置换组41例,全膝关节置换组68例。比较两组患者的平均住院时间、置换后并发症发生率、身体健康总评分、精神健康总评分、牛津膝关节评分以及置换后5年假体在位率。结果与结论:单髁置换组患者平均住院时间(4.21±2.44)d,较全膝关节置换组(6.11±2.23)d短(P=0.001)。两组患者置换后并发症发生率、身体健康总评分、精神健康总评分、牛津膝关节评分等方面差异均无显著性意义(P>0.05)。置换后5年,单髁置换组假体在位率(90%)较全膝关节置换组(100%)低(P<0.05)。提示对于单纯内侧胫股间室型膝关节骨关节炎患者,单髁置换与全膝关节置换具有相似的修复效果,但单髁置换后5年假体在位率稍低。 | 梁宁 Samuel Yih Shyan Wong Nick Clement Deborah MacDonald Daniel E Porter | 2015 | 中国组织工程研究2015，19，53： | 12 |
| 2 | Does aspirin or non-aspirin non-steroidal anti-inflammatory drug use prevent colorectal cancer in inflammatory bowel disease?显示文摘AIM: To determine whether aspirin or non-aspirin nonsteroidal anti-inflammatory drugs(NA-NSAIDs) prevent colorectal cancer(CRC) in patients with inflammatory bowel disease(IBD).METHODS: We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD related to aspirin or NANSAID use. Pooled odds ratios(OR) and 95%CIs were determined using a random-effects model. Publication bias was assessed using Funnel plots and Egger's test. Heterogeneity was assessed using Cochran's Q and the I2 statistic.RESULTS: Eight studies involving 14917 patients and 3 studies involving 1282 patients provided data on the risk of CRC in patients with IBD taking NA-NSAIDs and aspirin respectively. The pooled OR of developing CRC after exposure to NA-NSAIDs in patients with IBD was 0.80(95%CI: 0.39-1.21) and after exposure to aspirin it was 0.66(95%CI: 0.06-1.39). There was significant heterogeneity(I2 > 50%) between the studies. There was no change in the effect estimates on subgroup a na ly s e s o f t he po pulat io n s t udie d o r w he t he r adjustment or matching was performed.CONCLUSION: There is a lack of high quality evidence on this important clinical topic. From the available evidence NA-NSAID or aspirin use does not appear to be chemopreventative for CRC in patients with IBD. | Nick E Burr Mark A Hull Venkataraman Subramanian | 2016 | World Journal of Gastroenterology2016，22，13： | 6 |
| 3 | Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancer显示文摘 | HEASLEY L E THALER S NICKS M | 1997 | J Biol Chem1997，272，14： | 1 |
| 4 | Increased NADH-oxidase mediated superoxide production in the early stages of atherosclerosis显示文摘 | WARNHOLTZ A NICKEING G SCHULZ E | 1999 | Circulation1999，99，15： | 1 |
| 5 | Management of acute organophosphorus pesticide poisoning显示文摘 | Michael E Nick AB Peter E | 2008 | Lancet2008，371，9612： | 1 |
| 6 | Minimally invasive saphenous vein harvesting: effect on endothelial and smooth muscle function显示文摘 | EDWARD A B TOMAS J G NICK E J | 2001 | Ann Thorac Surg2001，71，： | 1 |
| 7 | Physical Activity and Physical Function in Older Adults With Knee Osteoarthritis 显示文摘 | Chmelo E Nick/as B Davis C | 2013 | J Phys Act Health2013，10，6： | 1 |
| 8 | Genomic regions determining resistance to leaf stripe (Pyrenophora graminea ) in barley显示文摘 | Arru L Nicks R E Lindhout P | 2002 | Genome2002，45，： | 1 |
| 9 | Management of acute or-ganophos-phorus pesticide poisoning显示文摘 | Michael E Nick AB Peter E | 2008 | Lancet2008，371，9612： | 1 |
| 10 | The Relationship of Hamstrings and Quadriceps Strength to Anterior Cruciate Ligament Injury in Female Athletes显示文摘 | Gregory D Myer Kevin R Ford Kim D Barber Foss Chunyan Liu Todd G Nick Timothy E Hewett | 2009 | Clinical Journal of Sport Medicine2009，，1： | 1 |
| 11 | Medical management of acute organophosphorus pesticide self-poisoning显示文摘 | Michael E Nick AB Peter E | 2008 | Lancet2008，371，9612： | 1 |
| 12 | Analyses of hydrogen sorption kinetics and thermodynamics of magnesium-misch metal alloys显示文摘 | Tran Nick E | 2006 | Alloys and Compds2006，，407： | 1 |
| 13 | Light induced reduction of rhodium(Ⅲ) and palladium(Ⅱ) on the titanium dioxide dispersions and the selective photochemical separation and recovery of gold(Ⅲ) platium(Ⅳ),and rhodium(Ⅲ) in chloride media显示文摘 | ENRICO B NICK S GARY E | 1986 | Inorg Chem1986，25，25： | 1 |
| 14 | Molecular ordering in HIV-induced apoptosis显示文摘 | Banki K Hutter E Nick J G | 1998 | J Biol Chem1998，273，11： | 1 |
| 15 | Auxin Redistribution during First Positive Phototropism in Corn Coleoptiles Microtubule Reorientation and the Cholodny-Went Theory显示文摘 | Nick P Schifer E Furuya M | 1992 | Plant Physiology1992，99，4： | 1 |
| 16 | Isolation,structure and activity of GID,a novel 4/7α-conotoxin with an extended N-terminal sequence显示文摘 | Nicke A Loughnan M L Millard E L | 2003 | J Biol Chem2003，278，： | 1 |
| 17 | A 2D numerical model of wave run-up and overtopping显示文摘 | Matthew E Hubbard Nick Dodd | 2002 | Coastal Engineering2002，，47： | 1 |
| 18 | Medical management of acute organophosphorus pesticide se1f-poisoning显示文摘 | Michael E Nick AB Peter E | 2012 | Lancet2012，371，9616： | 1 |
| 19 | Intelligent ship arrangements:A new approach to general arrangement显示文摘 | PARSONS M CHUNG H NICK E | 2008 | Journal of the American Society of Naval Engineers2008，120，3： | 1 |
| 20 | Activation of anthocyanin synthesis in Cymbidium orchids variability between known regulators显示文摘 | Nick W Albert Steve A Vern E Collette | 2010 | Plant Cell Tiss Organ Culture2010，100，3： | 1 |
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