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您的检索式：作者名="Nicholas ATinker"
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| 1 | An integrated framework reinstating the environmental dimension for GWAS and genomic selection in crops显示文摘Identifying mechanisms and pathways involved in gene–environment interplay and phenotypic plasticity is a long-standing challenge.It is highly desirable to establish an integrated framework with an environmental dimension for complex trait dissection and prediction.A critical step is to identify an environmental index that is both biologically relevant and estimable for new environments.With extensive field-observed complex traits,environmental profiles,and genome-wide single nucleotide polymorphisms for three major crops(maize,wheat,and oat),we demonstrated that identifying such an environmental index(i.e.,a combination of environmental parameter and growth window)enables genome-wide association studies and genomic selection of complex traits to be conducted with an explicit environmental dimension.Interestingly,genes identified for two reaction-norm parameters(i.e.,intercept and slope)derived from flowering time values along the environmental index were less colocalized for a diverse maize panel than for wheat and oat breeding panels,agreeing with the different diversity levels and genetic constitutions of the panels.In addition,we showcased the usefulness of this framework for systematically forecasting the performance of diverse germplasm panels in new environments.This general framework and the companion CERIS-JGRA analytical package should facilitate biologically informed dissection of complex traits,enhanced performance prediction in breeding for future climates,and coordinated efforts to enrich our understanding of mechanisms underlying phenotypic variation. | Xianran Li Tingting Guo Jinyu Wang Wubishet ABekele Sivakumar Sukumaran Adam EVanous James PMcNellie Laura Tibbs Cortes Marta SLopes Kendall RLamkey Mark EWestgate John KMcKay Sotirios VArchontoulis Matthew PReynolds Nicholas ATinker Patrick SSchnable Jianming Yu | 2021 | Molecular Plant2021，14，6： | 0 |
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