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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Rapid diagnosis of Entamoeba infection by using Entamoeba and Entamoeba histolytica stool antigen detection kits显示文摘 | Haque R Nevill LM Hahn P | 1995 | J Clin Microbiol1995，33，： | 2 |
| 3 | Radiometric correction of visible and infrared remote sensing data at the Canada Centre for Remote Sensing显示文摘 | AHERN F J Brown R J Cihlar J Gauthier R Murphy J Neville R A and Teillet P M | 1984 | International Journal of Remote Sensing1984，8，： | 2 |
| 4 | High performance concrete-- An overview显示文摘 | Neville A Aitcin P C | 1998 | Materials and Structures1998，31，3： | 2 |
| 5 | Integrated view of shrinkage deformation 显示文摘 | AITIN P C NEVILLE A ACKER P | 1997 | Concrete International1997，19，9： | 1 |
| 6 | High performance concrete--An overview显示文摘 | Neville A Aitcin P C | 1998 | Materials and Structures1998，31，3： | 1 |
| 7 | Experience with the generalized reciprocal method of seismic refraction interpretation for shallow engineering site investigation 显示文摘 | Hatherly P J Nevile M J | 1986 | Geophysics1986，51，： | 1 |
| 8 | Composite Metal Foams Processed Through Powder Metallurgy 显示文摘 | Neville B P Rabiei A | 2008 | Materials and Design2008，29，： | 1 |
| 9 | Non-Elastic Deformation of Concrete under Cyclic Compression 显示文摘 | Waley C P Neville A M | 1973 | Magazine of Concrete Research1973，25，84： | 1 |
| 10 | 103 Testing for clopidogrel and aspirin anti-platelet activity in patients with acute coronary syndromes (ACS):should we test,and if so when显示文摘 | A P Worrall V Amoah A Nevill | | 0，，： | 1 |
| 11 | Practice Nurse Use of Evi- dence in Clinical Practice: A Descriptive Survey显示文摘 | Prior P Wilkinson J Neville S | 2010 | Nurs Prax N Z2010，26，2： | 1 |
| 12 | Thyroid hormones and cortisol concentrations in offspring are influenced by maternal supranutritional selenium and nutritional plane in sheep 显示文摘 | Vonnahme K A Neville T L Lekatz L A Reynolds L P Hammer C J Redmer D A Caton J S | 2013 | Nutrition and Metabolic Insights2013，6，4： | 1 |
| 13 | Systemic lupus erythematosus, a disease associated with low levels of clusterin/apoJ, an antiinflammatory protein显示文摘 | Newkirk MM Apostolakos P Neville C | 1999 | J Rheumatol1999，26，3： | 1 |
| 14 | Impacts of maternal selenium supply and nutritional plane on visceral tissues and intestinal biology in 180 - day-old offspring in sheep 显示文摘 | Yuuusova R D Neville T L Vonnahme K A Hammer C J Reed J J Taylor J B Redmer D A Reynolds L P Eaton J S | 2013 | Journal of Animal Science2013，91，5： | 1 |
| 15 | Ovarian and uterine characteristics and onset of puberty in adolescent offspring: effects of maternal diet and selenium supplementation in sheep 显示文摘 | Grazul- Bilska A T Neville T L Borowczyk E Sharma A Reynolds L P Caton J S Redmer D A Vounahme K A | 2014 | Theriogeuology2014，81，7： | 1 |
| 16 | Non-elastic deformation of concrete under cyclic compression显示文摘 | WHALEY C P NEVILLE A M | 1973 | Magazine of Concrete Research1973，25，： | 1 |
| 17 | The basis of practical tanning systems reconciled with vegetable tanning theories显示文摘 | Neville D R Labbert P S | 1999 | JALCA1999，94，3： | 1 |
| 18 | Scleral remodeling during the development of and recovery from axial myopia in the tree shrew 显示文摘 | Neville AM Lawlor P Gentle A | 2000 | Invest Ophthalmol Vis Sci2000，41，12： | 1 |
| 19 | Effects of gestational plane of nutrition and selenium supplementation on mammary development and eolostrum quality in pregnant ewe lambs 显示文摘 | Swanson T J Hammer C J Luther J S Carlson D B Taylor J B Redmer D A Neville T L Reed J J Reynolds L P Caton J S Vonnahme K A | 2008 | Journal of Animal Science2008，86，9： | 1 |
| 20 | Do biometeorological indices improve modeling outcomes of heat-related mortality 显示文摘 | Vaneckova P Neville G Tippett V | 2011 | Journal of Applied Meteorology and Climatology2011，50，6： | 1 |
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