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| 1 | A rare case of hyaline-type Castleman disease in the liver显示文摘Castleman disease often develops in the neck, mediastinum and pulmonary hilum. Its onset in the peritoneal cavity is very rare. The patient, a woman in her 70s, was referred to our department for a detailed examination of an abdominal mass. On abdominal ultrasonography, computed tomography scan, magnetic resonance imaging and positron emission tomography, a mass approximately 15 mm in diameter was noted in the hepatic S6. We attempted radical treatment and conducted a laparoscope-assisted right lobectomy. On the basis of histopathological findings, the patient was diagnosed as having hyaline type Castleman disease in the liver, a very rare condition. | Hisaaki Miyoshi Shima Mimura Takako Nomura Joji Tani Asahiro Morishita Hideki Kobara Hirohito Mori Hirohito Yoneyama Akihiro Deguchi Takashi Himoto Naoki Yamamoto Keiichi Okano Yasuyuki Suzuki Tsutomu Masaki | 2013 | World Journal of Hepatology2013，5，7： | 14 |
| 2 | A Blowdown Cryogenic Cavitation Tunnel and CFD Treatment for Flow Visualization around a Foil显示文摘成穴是在火箭引擎的发展的主要问题之一。有很少试验性的研究设想低温实验法的陪衬成穴。因此, blowdown 类型的一条新低温实验法的成穴隧道被造。陪衬形状是鈥減l ano 凸的鈥吗?因为简洁,这侧面被选择,而且类似于为火箭 inducer impeller 的。工作液体是在房间温度,热水和液体氮的水。在攻击(AOA )=8 掳的角度的情况下,期刊洞离开在 90 掳 C 和氮在两水的实验被观察在 ? 在一样的速度下面的 190 掳 C 10 m/sec 和一样的成穴数 0.7。频率被观察分别地,是 110 和 90 Hz 并且几乎旋涡从陪衬流与那些与一致。温度消沉特别在低温实验法的成穴在实验和模拟由于热力学的效果被证实。关键词成穴 - 隧道 - 致冷剂 - CFD - 可视化 - 模拟 - 陪衬 CLC 数字 | Yutaka ITO Kazuya SAWASAKI Naoki TANI Takao NAGASAKI Toshio NAGASHIMA | 2005 | Journal of Thermal Science2005，14，4： | 6 |
| 3 | Cryogenic Cavitating Flow in 2D Laval Nozzle显示文摘Cavitation is one of the troublesome problems in rocket turbo pumps,and since most of high-efficiency rocket propellants are cryogenic fluids,so called 'thermodynamic effect' becomes more evident than in water.In the present study.numerical and experimental study of liquid nitrogen cavitation in 2D Laval nozzle was carried out ,so that the influence of thermodynamic effect was examined.It was revealed that temperature and cavitation have strong inter-relationship with each other in thermo-sensitive cryogenic fluids. | Naoki Tani Toshio Nagashima | 2003 | Journal of Thermal Science2003，12，2： | 3 |
| 4 | Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma显示文摘AIM To evaluate the inhibitory effects of deferasirox(DFX) against hepatocellular carcinoma(HCC) through basic and clinical studies.METHODS In the basic study, the effect of DFX was investigated in three hepatoma cell lines(Hep G2, Hep3 B, and Huh7), as well as in an N-nitrosodiethylamine-induced murine HCC model. In the clinical study, six advanced HCC patients refractory to chemotherapy were enrolled. The initial dose of DFX was 10 mg/kg per day and was increased by 10 mg/kg per day every week, until the maximum dose of 30 mg/kg per day. The duration of a single course of DFX therapy was 28 consecutive days. In the event of dose-limiting toxicity(according to the Common Terminology Criteria for Adverse Events v.4.0), DFX dose was reduced.RESULTS Administration of DFX inhibited the proliferation of hepatoma cell lines and induced the activation of caspase-3 in a dose-dependent manner in vitro. In the murine model, DFX treatment significantly suppressed the development of liver tumors(P < 0.01), and significantly upregulated the mR NA expression levels of hepcidin(P < 0.05), transferrin receptor 1(P < 0.05), and hypoxia inducible factor-1α(P < 0.05) in both tumor and non-tumor tissues, compared with control mice. In the clinical study, anorexia and elevated serum creatinine were observed in four and all six patients, respectively. However, reduction in DFX dose led to decrease in serum creatinine levels in all patients. After the first course of DFX, one patient discontinued the therapy. We assessed the tumor response in the remaining five patients; one patient exhibited stable disease, while four patients exhibited progressive disease. The one-year survival rate of the six patients was 17%.CONCLUSION We demonstrated that DFX inhibited HCC in the basic study, but not in the clinical study due to dose-limiting toxicities. | Issei Saeki Naoki Yamamoto Takahiro Yamasaki Taro Takami Masaki Maeda Koichi Fujisawa Takuya Iwamoto Toshihiko Matsumoto Isao Hidaka Tsuyoshi Ishikawa Koichi Uchida Kenji Tani Isao Sakaida | 2016 | World Journal of Gastroenterology2016，22，40： | 3 |
| 5 | Genetic structure within a Japanese stone pine (Pinus pumila regel) population on Mt. Aino-dake in central Honshu, Japan显示文摘 | Naoki Tani Nobuhiro Tomaru Yoshihiko Tsumura Masayuki Araki Kihachiro Ohba | 1998 | Journal of Plant Research1998，，1： | 1 |
| 6 | Preoperative detection and localization of small bowel hemangioma: Two case reports显示文摘Among the various diagnostic modalities for small bowel hemangioma,video capsule endoscopy(VCE)and double-balloon enteroscopy( BE)can be recommended as part of the work-up in patients with obscure gastrointestinal bleeding(OGIB). BE is superior to VCE in the accuracy of diagnosis and therapeutic potential,while in most cases total enteroscopy cannot be achieved through only the antegrade or retrograde BE procedures.As treatment for small bowel bleeding,especially spout bleeding,localization of the lesion for the decision of BE insertion facilitates early treatment,such as endoscopic hemostatic clipping,allowing patients to avoid useless transfusion and the worsening of their disease into life-threatening status.Applying endoscopic India ink marking prior to laparoscopic surgical resection is a particularly useful technique for more minimally invasive treatment.We report two cases of small bowel hemangioma found in examinations for OGIB that were treated with combination of laparoscopic and endoscopic modalities. | Nobuhisa Takase Keisuke Fukui Takafumi Tani Tohru Nishimura Tomohiro Tanaka Naoki Harada Kimihiko Ueno Manabu Takamatsu Akihiko Nishizawa Akiharu Okamura Kunihiko Kaneda | 2017 | World Journal of Gastroenterology2017，23，20： | 1 |
| 7 | Genetic structure within a Japanese stone pine (Pinus pumila regel) population on Mt. Aino-dake in central Honshu, Japan显示文摘 | Naoki Tani Nobuhiro Tomaru Yoshihiko Tsumura Masayuki Araki Kihachiro Ohba | 1998 | Journal of Plant Research1998，，1： | 1 |
| 8 | Community structure and growth habit of Siberian dwarf pine (Pinuspumila) 显示文摘 | Araki Masayuki Naoki Tani Araki Masatake | 1993 | Japanese Journal of Forestry Research1993，75，5： | 1 |
| 9 | Microsatellite markers reveal high allelic variation in natural populations of Cryptomeria japonica near refugial areas of the last glacial period显示文摘 | Tomokazu Takahashi Naoki Tani Hideaki Taira | 2005 | J Plant Res2005，118，： | 1 |
| 10 | A Consensus consensus linkage map for Sugi(Cryptomeria japonica)from two pedigrees, based on microsatellites and expressed sequence tags显示文摘 | Naoki Tani Tomokazu Takahashi Hiroyoshi Iwata | 2003 | Genetics2003，165，： | 1 |
| 11 | Laparoscopic splenectomy for patients with liver cirrhosis: Improvement of liver function in patients with Child-Pugh class B显示文摘 | Naoki Yamamoto Keiichi Okano Minoru Oshima Shitaro Akamoto Masao Fujiwara Joji Tani Hisaaki Miyoshi Hirohito Yoneyama Tsutomu Masaki Yasuyuki Suzuki | 2015 | Surgery2015，，6： | 1 |
| 12 | Calibration of Modified Spalart-Ailmaras Model Parameters for Linear Compressor Cascade Corner Flow显示文摘In this study,Bayesian parameter calibration is applied to Saplart-Allmaras(SA)turbulence model,and the prediction improvement by the calibrated model is demonstrated.The quantity of interest(QOI)is the pitch-wise distribution of Mach number in the comer separation flow region.The 10 model parameters included in the SA model with Rotation-Curvature correction are considered as random variables obeying uniform prior probability distributions.The order of generalized Polynomial Chaos(gPC)used for sensitivity analysis and surrogate model in calibration is incrementally increased during the calibration process.Posterior convergence is obtained at the 3rd order expansion level in this study.At this final level,sensitivity analysis indicates 3 model parameters,cbl,k and cr3 are the most influential random variables,and 3-parameter Bayesian calibration is conducted.The likelihood function in the Bayesian theorem is specified in the form of Gaussian distribution,including experimental uncertainty.The combination of prior and likelihood brings the posterior distribution of model parameters,and Maximum A Posterior(MAP)value is selected as a calibrated parameter set.The flow simulation with calibrated parameters shows a significant increase in the accuracy of the Mach number profile in the comer separation region.The increase in accuracy is attributed to enlarged turbulent viscosity due to the parameter modification of the turbulent viscosity source term.The calibrated parameter is also tested in the off-design flow field,not included in the calibration process.The calibrated CFD again shows improved accuracy for comer separation prediction,and the effectiveness of the parameter set outside of the calibration field is demonstrated. | MATSUI Kotaro PEREZ Ethan KELLY TRyan TANI Naoki JEMCOV Aleksandar | 2022 | Journal of Thermal Science2022，31，1： | 0 |
| 13 | True left-sided gallbladder with variations of bile duct and cholecystic vein显示文摘A left-sided gallbladder without a right-sided round ligament,which is called a true left-sided gallbladder,is extremely rare.A 71-year-old woman was referred to our hospital due to a gallbladder polyp.Computed tomography(CT) revealed not only a gallbladder polyp but also the gallbladder located to the left of the round ligament connected to the left umbilical portion.CT portography revealed that the main portal vein diverged into the right posterior portal vein and the common trunk of the left portal vein and right anterior portal vein.CT cholangiography revealed that the infraportal bile duct of segment 2 joined the common bile duct.Laparoscopic cholecystectomy was performed for a gallbladder polyp,and the intraoperative finding showed that the cholecystic veins joined the round ligament.A true left-sided gallbladder is closely associated with several anomalies; therefore,surgeons encountering a true left-sided gallbladder should be aware of the potential for these anomalies. | Hiromichi Ishii Akinori Noguchi Mie Onishi Koji Takao Takahiro Maruyama Hiroaki Taiyoh Yasunobu Araki Takeshi Shimizu Hiroyuki Izumi Naoki Tani Masahide Yamaguchi Tetsuro Yamane | 2015 | World Journal of Gastroenterology2015，21，21： | 0 |
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