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您的检索式：作者名="Nahed Ismail"
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| 1 | Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity显示文摘Efforts to mitigate the COVID-19 crisis revealed that fast,accurate,and scalable testing is crucial for curbing the current impact and that of future pandemics.We propose an optical method for directly imaging unlabeled viral particles and using deep learning for detection and classification.An ultrasensitive interferometric method was used to image four virus types with nanoscale optical path-length sensitivity.Pairing these data with fluorescence images for ground truth,we trained semantic segmentation models based on U-Net,a particular type of convolutional neural network.The trained network was applied to classify the viruses from the interferometric images only,containing simultaneously SARS-CoV-2,H1N1(influenza-A virus),HAdV(adenovirus),and ZIKV(Zika virus).Remarkably,due to the nanoscale sensitivity in the input data,the neural network was able to identify SARS-CoV-2 vs.the other viruses with 96%accuracy.The inference time for each image is 60 ms,on a common graphic-processing unit.This approach of directly imaging unlabeled viral particles may provide an extremely fast test,of less than a minute per patient.As the imaging instrument operates on regular glass slides,we envision this method as potentially testing on patient breath condensates.The necessary high throughput can be achieved by translating concepts from digital pathology,where a microscope can scan hundreds of slides automatically. | Neha Goswami Yuchen R.He Yu-Heng Deng Chamteut Oh Nahil Sobh Enrique Valera Rashid Bashir Nahed Ismail Hyunjoon Kong Thanh H.Nguyen Catherine Best-Popescu Gabriel Popescu | 2021 | Light(Science & Applications)2021，10，9： | 3 |
| 2 | Smith laboratory evaluation of a fully automated chemiluminescence immunoassay for rapid detection of HBsAg,antibodies to HBsAg,and antibodies to hepa- titis C virus显示文摘 | Nahed Ismail Geoffrey E Fish | 2004 | J Clin Microbiol2004，42，2： | 1 |
| 3 | Laboratory evaluation of a fully automated chemiluminescence immunoassay for rapid detec- tion of tfBsAg, antibodies to HBsAg, and antibodies to hepatitis C virus显示文摘 | Nahed Ismail GEF Michael BSmith | 2004 | J Clin Microbiol2004，42，2： | 1 |
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