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| 1 | Nature:通过控制血管生长来开发治疗癌症等多种疾病的新型疗法显示文摘最近,一项刊登在国际杂志Nature上的研究报告中,来自耶鲁大学的研究人员通过研究揭示了如何通过控制血管发育来帮助开发治疗心血管疾病以及癌症的新型疗法。 | Yu, Pengchun Wilhelm, Kerstin Dubrac, Alexandre Tung, Joe K. Alves, Tiago C. Fang, Jennifer S. Xie, Yi Zhu, Jie Chen, Zehua De Smet, Frederik Zhang, Jiasheng Jin, Suk-Won Sun, Lele Sun, Hongye Kibbey, Richard G. Hirschi, Karen K. Hay, Nissim Carmeliet, Peter Chittenden, Thomas W. Eichmann, Anne Potente, Michael Simons, Michael | 2017 | 现代生物医学进展2017，17，22： | 9 |
| 2 | Non-thermal laser driven plasma-blocks for proton boron avalanche fusion as direct drive option显示文摘Fusion energy from protons reacting with ^(11) B,HB11,is extremely difficult or impossible when using thermal ignition by laser irradiation.This changes radically when using picosecond laser pulses with powers above petawatts dominated by nonlinear force driven ultrahigh ac-celeration of plasma blocks for a non-thermal initiation of igniting solid density HB11 fuel.For a cylindrical trapping of the reaction,laser produced ultrahigh magnetic fields above kiloTesla,have to be combined.The experimentally confirmed highly increased HB11 fusion gains due to avalanche reaction may lead to a scheme of an environmentally clean and economic power reactor. | Heinrich Hora Shalom Eliezer Noaz Nissim Paraskevas Lalousis | 2017 | Matter and Radiation at Extremes2017，2，4： | 2 |
| 3 | A hardening load transfer function for rock bolts and its calibration using distributed fiber optic sensing显示文摘Confinement of rock bolts by the surrounding rock formation has long been recognized as a positive contributor to the pull-out behavior,yet only a few experimental works and analytical models have been reported,most of which are based on the global rock bolt response evaluated in pull-out tests.This paper presents a laboratory experimental setup aiming to capture the rock formation effect,while using distributed fiber optic sensing to quantify the effect of the confinement and the reinforcement pull-out behavior on a more local level.It is shown that the behavior along the sample itself varies,with certain points exhibiting stress drops with crack formation.Some edge effects related to the kinematic freedom of the grout to dilate are also observed.Regardless,it was found that the mid-level response is quite similar to the average response along the sample.The ability to characterize the variation of the response along the sample is one of the many advantages high-resolution fiber optic sensing allows in such investigations.The paper also offers a plasticity-based hardening load transfer function,representing a'slice'of the anchor.The paper describes in detail the development of the model and the calibration/determination of its parameters.The suggested model captures well the coupled behavior in which the pull-out process leads to an increase in the confining stress due to dilative behavior. | Assaf Klar Ori Nissim Itai Elkayam | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，11： | 2 |
| 4 | Ratio Analysis and Equity Valuation: From Research to Practice显示文摘 | Doron Nissim Stephen H. Penman | 2001 | Review of Accounting Studies2001，，1： | 2 |
| 5 | Barrett's esophagus with high grade dysplasia is associated with non-esophageal cancer显示文摘AIM To study factors associated with esophageal and nonesophageal cancer morbidity among Barrett's esophagus(BE) patients. METHODS A cohort study within a single tertiary center included 386 consecutive patients with biopsy proven BE, who were recruited between 2004-2014. Endoscopic and histologic data were prospectively recorded. Cancer morbidity was obtained from the national cancer registry. Main outcomes were BE related(defined as esophagus and cardia) and non-BE related cancers(all other cancers). Cancer incidence and all-causemortality were compared between patients with highgrade dysplasia(HGD) and with low-grade or no dysplasia(non-HGD) using Kaplan-Meier curves and cox regression models.RESULTS Of the 386 patients, 12 had HGD, 7 had a BE related cancer. There were 75(19.4%) patients with 86 cases of lifetime cancers, 76 of these cases were non-BE cancers. Seven(1.8%) and 18(4.7%) patients had BE and non-BE incident cancers, respectively. Twelve(3.1%) patients had HGD as worst histologic result. Two(16.7%) and 16(4.4%) incident non-BE cancers occurred in the HGD and non-HGD group, respectively. Ten-year any cancer and non-BE cancer free survival was 63% and 82% in the HGD group compared to 93% and 95% at the non-HGD group, respectively. Log-rank test for patients with more than one endoscopy, assuring longer follow up, showed a significant difference(P < 0.001 and P = 0.017 respectively). All-cause mortality was not significantly associated with BE HGD.CONCLUSION Patients with BE and HGD, may have a higher risk for all-cause cancer morbidity. The implications on cancer prevention recommendations should be further studied. | Nir Bar Naama Schwartz Michal Nissim Naomi Fliss-Isacov Shira Zelber-Sagi Revital Kariv | 2018 | World Journal of Gastroenterology2018，24，39： | 2 |
| 6 | Double emulsions-scope, limitations and new achievements 显示文摘 | Nissim Garti | 1997 | Colloids and Surfaces A: Physicochemical and Engineering Aspects1997，，： | 1 |
| 7 | Dynamic Control of Polymovphic Transformation in Triglycerides by Surfactants :The Button Syndrome 显示文摘 | Judith Schlichter Aronhirne Sara Sarig Nissim Garti | 1988 | JAOCS1988，65，7： | 1 |
| 8 | Targeting by affinity-matured recombinantantibody fragments of an angiogenesis associated fibronectin isoform显示文摘 | Neri D Carnemolla B Nissim A | 1997 | Nat Biotechnol1997，15，： | 1 |
| 9 | Microemulsions as microreactors for food applications显示文摘 | Nissim G | 2003 | Current Opinion in Colloid and Interface Science2003，8，： | 1 |
| 10 | Up stream and downstream of mTOR显示文摘 | Nissim H Nahmn S | 2004 | Genes Dev2004，18，16： | 1 |
| 11 | Pesponse of br&in &mino &cid met&bolism to ketosis显示文摘 | Yudkoff N D&ikhin Y Nissim i et aI | 2005 | Neurochem 1nt2005，47，12： | 1 |
| 12 | Equity valuation using multiples显示文摘 | Liu J Nissim D Thomas J | 2002 | Journal of Accounting Research2002，40，1： | 1 |
| 13 | The Persistence of the Accruals Anomaly 显示文摘 | Lev B Nissim D | 2006 | Contemporary Accounting Research2006，23，1： | 1 |
| 14 | Penman,Financial Statement Analysis of Leverage and How It Informs About Profitability and Price-to-Book Ratios显示文摘 | Doron Nissim Stephen H | 2003 | Review of Accounting Studies2003，，4： | 1 |
| 15 | Microemulsions as transdermal drug delivery vehicles 显示文摘 | Anna K Nissim G | 2006 | Advances in Colloid and Interface Science2006，，： | 1 |
| 16 | Targeting by affinity- matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform显示文摘 | Neri D Carnemolla B Nissim A | 1997 | Nat Biotechnol1997，15，12： | 1 |
| 17 | Ratio Analysis and Equity Valuation: From Research to Practice显示文摘 | Doron Nissim Stephen H. Penman | 2001 | Review of Accounting Studies2001，，1： | 1 |
| 18 | Progress in stabilization and transport phenomena of double emulsions in food applications 显示文摘 | Nissim Garti | 1997 | Lebensmitted-Wissensehaft und-Technologie1997，30，3： | 1 |
| 19 | Rapid and accurate determination of D- and L-lactate, lactose and galactose by enzymatic reactions coupled to formation of a fluorochromophore: Applications in food quality control显示文摘 | Fira Shapiro Nissim Silanikove | 2010 | Food Chemistry2010，119，： | 1 |
| 20 | Calibrating Noise to Sensitivity in Private Data Analysis显示文摘 | Dwork C McSherry F Nissim K | 2006 | Theory of Cryptog- raphy2006，25，20： | 1 |
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