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| 1 | Outcomes of furazolidone-and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication显示文摘AIM To evaluate the outcomes of furazolidone-and amoxicillin-based quadruple therapy for treatment of Helicobacter pylori(H. pylori) infection and identify predictors of failed eradication.METHODS Patients with H. pylori infection treated with furazolidone, amoxicillin, bismuth, and proton pump inhibitor therapy(January 2015 to December 2015) who received the ^(13)C-urea breath test > 4 wk after treatment were evaluated. Demographic and clinical data including prior H. pylori treatment attempts, medication adherence, alcohol and cigarette consumption during therapy, and treatment-related adverse events were recorded by reviewing medical records and telephone surveys. H. pylori eradication rates for overall and subgroups were evaluated. Multivariate analysis was performed to identify independent predictors of failed H. pylori eradication.RESULTS Of the 992 patients treated and retested for H. pylori infection, the overall eradication rate was 94.5% [95% confidence interval(CI): 94.1%-95.9%]. H. pylori eradication rate of primary therapy was 95.0%(95%CI: 93.5%-96.5%), while that of rescue therapy was 91.3%(95%CI: 86.8%-95.8%). Among the 859 patients who completed the study protocol, 144(17%) reported treatment-related adverse events including 24(3%) leading to premature discontinuation. On multivariate analysis, poor medication adherence [adjusted odds ratio(AOR) = 6.7, 95%CI: 2.8-15.8], two or more previous H. pylori treatments(AOR = 7.4, 95%CI: 2.2-24.9), alcohol consumption during therapy(AOR = 4.4, 95%CI: 1.5-12.3), and possibly smoking during therapy(AOR = 1.9, 95%CI: 0.9-4.3) were associated with failed H. pylori eradication. CONCLUSION Furazolidone-and amoxicillin-based quadruple therapy for H. pylori infection in an area with a high prevalence of clarithromycin resistance demonstrated high eradication rates as primary and rescue therapies with a favorable safety profile. Patient education targeting abstinence from alcohol during therapy and strict medication adherence may further optimize H. pylori eradication. | Ya-Wen Zhang Wei-Ling Hu Yuan Cai Wen-Fang Zheng Qin Du John J Kim John Y Kao Ning Dai Jian-Min Si | 2018 | World Journal of Gastroenterology2018，24，40： | 18 |
| 2 | Nutrient Intakes of Pregnant Women and their Associated Factors in Eight Cities of China: A Cross-sectional Study显示文摘 | Fang-Li Liu Yu-Mei Zhang Gerard Vinyes Pares Kathleen C Reidy Wen-Zhi Zhao Ai Zhao Cheng Chen Celia Y Ning Ying-Dong Zheng Pei-Yu Wang | 2015 | Chinese Medical Journal2015，，13： | 12 |
| 3 | Association between adiponectin concentrations and diabetic retinopathy in patients with type 2 diabetes: a meta analysis显示文摘 | Fan XH Wu QH Hao YH Ning N Kang Z Cui Y Liu RH | 2014 | Chinese Medical Journal2014，，4： | 8 |
| 4 | Association of polymorphisms in the vascular endothelial growth factor gene and its serum levels with diabetic retinopathy in Chinese patients with type 2 diabetes: A cross-sectional study显示文摘 | Fan XH Wu QH Li Y Hao YH Ning N Kang Z Cui Y Liu RH | 2014 | Chinese Medical Journal2014，，4： | 4 |
| 5 | A Faraday current sensor using a novel multi-optic-loop sensing element 显示文摘 | NING Y N WANG Z P PALMER A W | 1995 | Meas Sci & Technol1995，6，： | 2 |
| 6 | Miniature Faraday current sensor based on multiple critical angle reflections in a bulk-optic ring 显示文摘 | NING Y N CHUB C B JACKSON D A | 1991 | Opt Lett1991，16，24： | 2 |
| 7 | Faraday current sensor that uses a triangular-shaped bulk-optic sensing element 显示文摘 | CHU B C B NING Y N JACKSON D A | 1992 | Opt Lett1992，17，16： | 2 |
| 8 | Faraday effect optical current clamp using a bulk-glass sensing element 显示文摘 | NING Y N JACKSON D A | 1993 | Opt Lett1993，18，10： | 2 |
| 9 | QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTO-DETECTOR-ⅠOPTICAL ASPECTS显示文摘A complete quantum mechanical model for GaAs?AlGaAs quantum well infrared photodetectors(QWIPs) is presented here. The model consisted of four parts: (1) Starting with the description of the electromagnetic field of the infrared radiation in the QWIP, effective component of the vector potential <| A z |> along the QWIP growth direction ( z axis) due to the optical diffraction grating was calculated. (2) From the wave transmissions and the occupations of the electronic states, it was discussed that the dark current in the QWIP is determined by the drift diffusion current of carriers thermally excited from the ground sublevel in the quantum well to extended states above the barrier. (3) The photocurrent was investigated by the optical transition (absorption coefficient between the ground state to excited states due to the nonzero <| A z |> ). (4) By studying the inter diffusion of the Al atoms across the GaAs?AlGaAs heterointerfaces,the mobility of the drift diffusion carriers in the excited states was calculated, so the measurement results of the dark current and photocurrent spectra can be explained theoretically. With the complete quantum mechanical descriptions of (1 4), QWIP device design and optimization are possible. | Fu Y Willander M Li Ning Lu W | 2002 | 红外与毫米波学报2002，21，5： | 2 |
| 10 | Treatment of organic pollutants in coke plant wastewater by the method of ultrasonic irradiation, catalytic oxidation and activated sludge显示文摘 | NING P BART H J JIANG Y J | 2005 | Separation and Purification Technology2005，41，2： | 1 |
| 11 | Myeloid sarcomas :a histologic, immunohistochemical, and cytogenetic study 显示文摘 | Alexiev B A Wang W Ning Y | 2007 | Diagn Pathol2007，31，2： | 1 |
| 12 | Preparation and Evaluation of Proliposomes Containing Clotrimazole 显示文摘 | Ning M Y Guo Y Z Pan H Z | 2005 | Chem Pharm Bull2005，53，6： | 1 |
| 13 | General Mandelbrot Sets and Julia Sets with color symmetry from equivalent mappings of the modular group 显示文摘 | Chung K W Chan H S Y Chen Ning | 2000 | Computer & Graphics2000，24，6： | 1 |
| 14 | A hierarchical path view model for path finding in Intelligent Transportation Systems显示文摘 | HUANG Y W NING J RUNDENSTEINER E A | 1997 | GeoInformatica1997，1，2： | 1 |
| 15 | Mammalian Apoptosis-Assoiated Genes c-myc and p53 in Maize: Homologs and Their Locations显示文摘 | Ning S B Song Y C Wang L | 2000 | International J of Cytology(Cytologia)2000，65，3： | 1 |
| 16 | Flame-retardant and smoke-suppressant properties of zinc borate and aluminium trihydrate-filled rigid PVC 显示文摘 | Ning Y Guo S | 2000 | Journal of Applied Polymer Science2000，77，14： | 1 |
| 17 | Relationship of urinary bisphenol Aconcentration to risk for prevalent type-2 diabetes in Chinese adults显示文摘 | Ning G Bi Y Wang T | 2011 | Annal Internal Med2011，155，6： | 1 |
| 18 | On the microstructure of biocomposites sintered from Ti,HA and bioactive glass显示文摘 | Ning CQ Zhou Y | | 0，，17： | 1 |
| 19 | Association of MHC class-Ⅲgene polymorphisms with ER-positive breast cancer in Chinese Han population显示文摘 | Pan Q Ning Y Chen LZ | 2012 | Genet Mol Res2012，11，4： | 1 |
| 20 | The research of degradability of a novel biodegradable coralline hydroxyapatite after implanted into rabbilt显示文摘 | Ning Y Wei T Pefu C | 2009 | Biomed mter res A2009，88，3： | 1 |
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