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| 1 | Targeting orthotopic gliomas with renal-clearable luminescent gold nanoparticles显示文摘在 nanomedicine 的主要临床的翻译挑战是在主要机关与举起和非可能减解的 nanoparticles (NP ) 的长期的保留联系的毒性的潜力。经历肾的清理的无机的 NP 的发展能潜在地解决这颗重要 biosafety 担心。然而,能被肾排泄的无机的 NP 是否仍然保持能够与差的渗透指向肿瘤,仍然保持不清楚。Glioblastoma multiforme,最恶意的 orthotopic 大脑肿瘤,因为血大脑障碍和反应 microglia 和 macroglia 的柔韧的血肿瘤障碍,在肿瘤微型环境为 NP 交货提出唯一的挑战。此处,我们使用了 orthotopic 调查在直径的 3 nm 的谷胱甘肽涂的金 nanoparticles (AuNPs ) 的被动指向的鼠科的 glioma 模型经历没能经历肾的清理的肾的清理和 18-nm AuNPs。显著地,我们报导 3-nm AuNPs 能与更高的效率指向 intracranial 肿瘤纸巾(2.3ver 在 1.0 妈骑车的 100 | Chuanqi Peng Xiaofei Gao Jing Xu Bujie Du Xuhui Ning Shaoheng Tang Robert M. Bachoo Mengxiao Yu Woo-Ping Ge Jie Zheng | 2017 | Nano Research2017,10,4: | 3 |
| 2 | Geochemistry, U-Pb, Hf isotopic characteristics and geological significance of Zhalaxiageyong trachydacite in Tuotuohe area, Qinghai显示文摘The Zhalaxiageyong lead-zinc-copper polymetallic deposit is a typical porphyry deposit of the Tuotuohe area. Whole-rock geochemical analyses,Zircon U-Pb dating and Hf isotope analysis are undertaken for the ore host trachydacite with the aim of constraining its petrogenesis,magma source and regional tectonic setting.LA-ICP-MS zircon U-Pb dating indicates that the trachydacite was formed in 32. 68 ± 0. 50 Ma( MSWD =1. 6),i. e.,Oligocene. The trachydacite is rich in potassium and poor in Mg#( 5. 10-9. 70),belonging to the peraluminous shoshonite series. The rocks are enriched in LILE( large ion lithophile elements) Rb,Ba,K and LREE,depleted in HFSE( high field strength elements) Nb,Ta,P,Ti,with high Sr and low Y and Yb,having the characteristics of the C type adakite. It is calculated that the initial εHf( t) of the zircons range from-0. 92 to 2. 07 and their two-stage Hf model ages T_(DM2) range from 978 Ma to 1 169 Ma. The magma source should be mainly the partially melt mafic rocks of the thickened Middle Neoproterozoic lower crust of the Northern Qiangtang massif with the addition of ancient aluminosilica material in the melting process. The rocks formed in the tectonic setting of delamination of lithosphere and extension of the thickened crust. During the period of 40-32 Ma,large-scale potassium rich alkaline magmatism occurred in this area. The porphyry metallogenesis is related to the magmatic activities in this period. | ZHANG Junyi LI Bile ZHAO Guoquan NING Chuanqi SUN Jing WANG Guozhi | 2017 | Global Geology2017,20,3: | 1 |
| 3 | Songjianghe biotite monzonitic granite zircon U-Pb geochronology and geochemical significance显示文摘The authors studied geochronology and geochemical data of the Songjianghe biotite monzogranite in the southern Zhangguangcai Range in order to determine its formation age,magma source,and tectonic environment. The results indicate that the Songjianghe biotite monzogranite was formed in the Middle Jurassic with an age of 168. 2 ± 2. 0 Ma( MSWD = 0. 93). The monzogranite was characterized by high alkali and low Ca O and Mg O,belonging to high-potassium calc-alkaline,metaluminous I-type granite. The rock is enriched in large ion lithophile elements such as Rb,Ba,and K and strongly depleted high field strength elements such as P,Ti,Nb,and Ta. It is concluded that the Songjianghe biotite monzogranite was derived from partial melting of amphibolite facies metamorphism mafic lower-crust and its formation was controlled by the Pacific Plate subduction. | WANG Guozhi LI Bile PENG Bo NING Chuanqi YANG Wenlong | 2016 | Global Geology2016,19,3: | 0 |
| 4 | Hydrogen-assisted activation of N_(2)molecules on atomic steps of ZnSe nanorods显示文摘Electrochemical reduction reaction of nitrogen(NRR)offers a promising pathway to produce ammonia(NH_(3))from renewable energy.However,the development of such process has been hindered by the chemical inertness of N_(2).It is recently proposed that hydrogen species formed on the surface of electrocatalysts can greatly enhance NRR.However,there is still a lack of atomiclevel connection between the hydrogenation behavior of electrocatalysts and their NRR performance.Here,we report an atomistic understanding of the hydrogenation behavior of a highly twinned ZnSe(T-ZnSe)nanorod with a large density of surface atomic steps and the activation of N_(2)molecules adsorbed on its surface.Our theoretical calculations and in situ infrared spectroscopic characterizations suggest that the atomic steps are essential for the hydrogenation of T-ZnSe,which greatly reduces its work function and efficiently activates adsorbed N_(2)molecules.Moreover,the liquid-like and free water over T-ZnSe promotes its hydrogenation.As a result,T-ZnSe nanorods exhibit significantly enhanced Faradaic efficiency and NH3 production rate compared with the pristine ZnSe nanorod.This work paves a promising way for engineering electrocatalysts for green and sustainable NH3 production. | Kun Du Xiuyao Lang Yuanyuan Yang Chuanqi Cheng Ning Lan Kangwen Qiu Jing Mao Weichao Wang Tao Ling | 2023 | Nano Research2023,16,5: | 0 |
| 5 | A NATIONAL SYSTEM OF INNOVATION TO BE BUILT FOR WELCOMING THE ERA OF KNOWLEDGE ECONOMY显示文摘Editor’s note: Not long ago, CAS headquarters put forward a proposal entitled 'A national innovation system (NIS) to be built up towards the era of knowledge economy (KE)' in a bid to plot a chart for China’s development in the next century. The suggestion was highly valued by the CPC Central Committee and here we publish an extracted translation of its full text. | (Chinese Academy of Sciences) He Chuanqi, Li Ning, Zhang Feng, Tian Ming, Huo Mingyuan | 1998 | Bulletin of the Chinese Academy of Sciences1998,12,3: | 0 |