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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Making gra- phene visible 显示文摘 | Blake P Hill E W Neto A H C | 2007 | Applied Physics Letters2007，91，06： | 1 |
| 3 | Dynamicsand structure formation in thin polymer melt films 显示文摘 | Seemann R Herminghaus S Neto C Schlagowski S Podzimek D Konrad R Mantz H Jacobs K | 2005 | Journal of Physics2005，17，9： | 1 |
| 4 | Superconducting states of pure and doped graphene 显示文摘 | Uchoa B Neto A H C | 2007 | Physical Review Letters2007，98，14： | 1 |
| 5 | Epidemiology of ocular allergy and co-morbidities inadolescents显示文摘 | GERALDINI M CHONG NETO H J RIEDI C A | 2013 | J Pediatr2013，89，： | 1 |
| 6 | Using open data technology to connect libraries, archives and museums: A Machadian case显示文摘 | Neto ALD Marcondes C H Pereira D V | 2013 | Transinformacao2013，25，1： | 1 |
| 7 | Nitriding of titanium disks and industrial dental implants using hollow cathode discharge显示文摘 | Jr ALVES C GUERRA NETO C L B MORAIS G H S | 2006 | Surface and Coatings Technology2006，200，： | 1 |
| 8 | The electronic properties of graphene显示文摘 | Neto A H C Guinea F Peres N M R | 2009 | Reviews of Modern Physics2009，81，1： | 1 |
| 9 | Diallel analysis and mapping of aluminum tolerance in corn inbred lines 显示文摘 | Conceicao L D H C S Tessel E C Neto J F B | 2009 | Maydica2009，54，1： | 1 |
| 10 | Boundary slip in Newtonian studies reports on progress in physics显示文摘 | NETO C EVANS D R BUTT H J | 2005 | 68:2859-28972005，68，： | 1 |
| 11 | The electronic properties of graphene显示文摘 | Neto A H C Guinea F Peres N | 2009 | Rev Mod Phys2009，81，： | 1 |
| 12 | On the Use of the Open Photoacoustic Ceil Technique for Studying Photosynthetic 02 EvoLution of Undetached Leaves: Comparison with Clark-type 02 Electrode显示文摘 | PEREIRA A C NETO G VARGAS H | 1994 | Rev Sci Instrum1994，65，： | 1 |
| 13 | Electronic properties of graphene multilayers显示文摘 | Nilsson J Neto A H C Guinea F Peres N M R | 2006 | Phys Rev Lett2006，97，26： | 1 |
| 14 | Liquid - liquid extraction of proteases from fermented broth by PEG/citrate aqueous two-phase system 显示文摘 | Porto T S Silva G M M Porto C S Cavalcanti M T H Neto B B Lima F J L Converti A Porto A L F Pessoa J A | 2008 | Chemical Engineering and Processing2008，47，4： | 1 |
| 15 | Chemical at-tributes and carbon stocks in an Oxisol under no - tillage in sa-vannah of Piaui state 显示文摘 | Leite L F C Galvao S R S Neto M R H | 2010 | Revista Brasileira de EngenhariaAgricola e Ambiental2010，14，12： | 1 |
| 16 | The electronic properties of graphene显示文摘 | Neto A H C Guinea F Peres N M R | | 0，，01： | 1 |
| 17 | Electronic Properties of Disordered Two-Dimensional Carbon显示文摘 | Peres N M R Guinea F Neto A H C | 2006 | Physical Review B Condensed Matter2006，73，12： | 1 |
| 18 | The electronic properties of graphene显示文摘 | Neto A H C Guinea F Peres N M R | | 0，，： | 1 |
| 19 | The electronic properties of graphene显示文摘 | Neto A H C Guinea F Peres N | 2009 | Reviews of modern physics2009，81，1： | 1 |
| 20 | Boundary slip in Newtonian liquids: A review of experimental studies 显示文摘 | Neto C Evans D R Butt H J | 2005 | Reports on Progress in Physics2005，68，12： | 1 |
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