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1Pulmonary involvement in inflammatory bowel disease显示文摘AIM:To determine the relationship of pulmonary abnormalities and bowel disease activity in inflammatory bowel disease(IBD).METHODS:Thirty ulcerative colitis(UC)and nine Crohn's disease patients,and 20 control subjects were enrolled in this prospective study.Detailed clinical information was obtained.Extent and activity of the bowel disease were established endoscopically.Each patient underwent pulmonary function tests and high-resolution computed tomography(HRCT).Blood samples for measurement of C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),angiotensin converting enzyme and total IgE were delivered by the patients.RESULTS:Ten(25.6%)patients had respiratory symptoms.A pulmonary function abnormality was present in 22 of 39 patients.Among all patients,the most prevalent abnormalities in lung functions were a decrease in forced expiratory volume in 1 s(FEV1),FEV1/forced vital capacity(FVC),forced expiratory flow(FEF)25%-75%,transfer coefficient for carbon monoxide(DLCO),DLCO/alveolar volume.Increased respiratory symptoms score was associated with high endoscopic activity index in UC patients.Endoscopic and clinical activities in UC patients were correlated with FEV1,FEV1/FVC,and FEF 25%-75%.Smoking status,duration of disease and medication were not correlated with pulmonary physiological test results,HRCT abnormalities,clinical/endoscopic disease activity,CRP,ESR or total IgE level or body mass index.CONCLUSION:It is important that respiratory manifestations are recognized and treated early in IBD.Otherwise,they can lead to destructive and irreversible changes in the airway wall.Aydin Yilmaz Nilgün Yilmaz Demirci Derya Hosgün Enver ner Yurdanur Erdogan Atila Gkek Atalay aglar 2010World Journal of Gastroenterology2010,16,39:15
2Recurrent anterior shoulder instability: Review of the literature and current concepts显示文摘The purpose of this review article is to discuss the clinical spectrum of recurrent traumatic anterior shoulder instability with the current concepts and controversies at the scientific level. Because of increasing participation of people from any age group of the population in sports activities, health care professionals dealing with the care of trauma patients must have a thorough understanding of the anatomy, patho-physiology, risk factors, and management of anterior shoulder instability. The risk factors for recurrent shoulder dislocation are young age, participation in high demand contact sports activities, presence of Hill-Sachs or osseous Bankart lesion, previous history of ipsilateral traumatic dislocation, ipsilateral rotator cuff or deltoid muscle insufficiency, and underlying ligamentous laxity. Achieving the best result for any particular patient depends onthe procedure that allows observation of the joint surfaces, provides the anatomical repair, maintains range of motion, and also can be applied with low rates of complications and recurrence. Although various surgical techniques have been described, a consensus does not exist and thus, orthopedic surgeons should follow and try to improve the current evidence-based treatment modalities for the patients.Hakan Sofu Sarper Gürsu Nizamettin Ko?kara Ali ?ner Ahmet Issιn Yalkιn ?amurcu 2014World Journal of Clinical Cases2014,2,11:10
3Dating of zircon from high-grade rocks:Which is the most reliable method?显示文摘Magmatic zircon in high-grade metamorphic rocks is often characterized by complex textures as revealed by cathodoluminenscence(CL) that result from multiple episodes of recrystallization,overgrowth,Pb-loss and modifications through fluid-induced disturbances of the crystal structure and the original U-Th-Pb isotopic systematics.Many of these features can be recognized in 2-dimensionaI CL images,and isotopic analysis of such domains using a high resolution ion-microprobe with only shallow penetration of the zircon surface may be able to reconstruct much of the magmatic and complex postmagmatic history of such grains.In particular it is generally possible to find original magmatic domains yielding concordant ages.In contrast,destructive techniques such as LA-ICP-MS consume a large volume,leave a deep crater in the target grain,and often sample heterogeneous domains that are not visible and thus often yield discordant results which are difficult to interpret.We provide examples of complex magmatic zircon from a southern Indian granulite terrane where SHRIMP Ⅱ and LA-ICP-MS analyses are compared.The SHRIMP data are shown to be more precise and reliable,and we caution against the use of LA-ICP-MS in deciphering the chronology of complex zircons from high-grade terranes.Alfred Krner Yusheng Wan Xiaoming Liu Dunyi Liu 2014Geoscience Frontiers2014,5,4:9
4Comparison of subconjunctivally injected bevacizumab, ranibizumab, and pegaptanib for inhibition of corneal neovascularization in a rat model显示文摘AIM: To compare the efficacies of subconjunctival bevacizumab, ranibizumab, and pegaptanib sodium injections for the inhibition of corneal neovascularization in an experimental rat model. METHODS: Sixteen corneas of 16 rats were chemically cauterized and randomized into four groups: bevacizumab group that treated with 0.05mL/1.25mg bevacizumab, ranibizumab group that treated with 0.05mL/0.5mg ranibizumab, pegaptanib group that treated with 0.05mL/0.15mg pegaptanib sodium, and control group that treated with 0.05mL saline solution. Digital photographs of the corneas were taken and analyzed using an image analysis software program. All corneas were excised and examined histologically on the 15 th day. RESULTS: Each treatment group had significantly less neovascularized corneal areas and fewer blood vessels than the control group (all P <0.05). In addition, bevacizumab group had significantly less neovascu-larized corneal areas and fewer blood vessels than ranibizumab and pegaptanib groups (both P <0.05). However, there was no significant difference between the ranibizumab and pegaptanib groups regarding percentage of neovascularized corneal areas and number of blood vessels (both P >0.05). CONCLUSION: Subconjunctival bevacizumab, ranibiz-umab, and pegaptanib sodium were effective with no corneal epitheliopathy for inhibiting corneal neovascularization after corneal burn in rats .Bevacizumab was more effective than ranibizumab and pegaptanib sodium.Ebru Eren Akar Veysi ner Cem Küükerdnmez Yonca Aydin Akova 2013International Journal of Ophthalmology(English edition)2013,6,2:9
5东秦岭深源麻粒岩包体的性质及其构造意义显示文摘岩相学、岩石化学、矿物温压计和单颗粒锆石 Pb-Pb 年代学综合研究表明,出露于桐柏地区秦岭杂岩中的麻粒岩包体是在早古生代(470Ma)秦岭洋壳消减过程中,俯冲板片在大约30—40km 深度经受麻粒岩相变质(470—435Ma 之间),随后其残片被花岗闪长质岩浆捕虏而上侵就位(435Ma)。古秦岭洋壳俯冲、变质、分熔乃至上侵这一系列构造过程都可以从麻粒岩包体研究结果中得到理想的印证。孙勇 于在平 A.Krner 1993地球化学1993,22,3:9
6Artificial intelligence in gastroenterology: A state-of-the-art review显示文摘The development of artificial intelligence(AI)has increased dramatically in the last 20 years,with clinical applications progressively being explored for most of the medical specialties.The field of gastroenterology and hepatology,substantially reliant on vast amounts of imaging studies,is not an exception.The clinical applications of AI systems in this field include the identification of premalignant or malignant lesions(e.g.,identification of dysplasia or esophageal adenocarcinoma in Barrett’s esophagus,pancreatic malignancies),detection of lesions(e.g.,polyp identification and classification,small-bowel bleeding lesion on capsule endoscopy,pancreatic cystic lesions),development of objective scoring systems for risk stratification,predicting disease prognosis or treatment response[e.g.,determining survival in patients post-resection of hepatocellular carcinoma),determining which patients with inflammatory bowel disease(IBD)will benefit from biologic therapy],or evaluation of metrics such as bowel preparation score or quality of endoscopic examination.The objective of this comprehensive review is to analyze the available AI-related studies pertaining to the entirety of the gastrointestinal tract,including the upper,middle and lower tracts;IBD;the hepatobiliary system;and the pancreas,discussing the findings and clinical applications,as well as outlining the current limitations and future directions in this field.Paul T Kröner Megan ML Engels Benjamin S Glicksberg Kipp W Johnson Obaie Mzaik Jeanin E van Hooft Michael B Wallace Hashem B El-Serag Chayakrit Krittanawong 2021World Journal of Gastroenterology2021,27,40:6
7Exact solutions of nonlinear fractional differential equations by (G'/G)-expansion method显示文摘In this paper,we use the fractional complex transform and the(G'/G)-expansion method to study the nonlinear fractional differential equations and find the exact solutions.The fractional complex transform is proposed to convert a partial fractional differential equation with Jumarie’s modified Riemann–Liouville derivative into its ordinary differential equation.It is shown that the considered transform and method are very efficient and powerful in solving wide classes of nonlinear fractional order equations.Ahmet Bekir zkan Güner 2013Chinese Physics B2013,22,11:5
8具有超高湿色牢度的聚酰胺染色显示文摘描述了瑞士Huntsman纺织效果公司开发的具有超高湿色牢度的聚酰胺染色技术。讨论了艳丽牢活性染料和已获专利的Eriofast micro染色工艺。通过开发一系列专为聚酰胺染色设计的具有深浓色泽且可重现的活性酸性染料,获得了在所有常用水洗条件下从未达到的水洗牢度和湿色牢度。F.Grüner J.Schmiedl 徐小茗(译) 钟毅(校) 2007国际纺织导报2007,35,4:3
9SHRIMP zircon dating and LA-ICPMS Hf analysis of early Precambrian rocks from drill holes into the basement beneath the Central Hebei Basin,North China Craton显示文摘The Central Hebei Basin(CHB) is one of the largest sedimentary basins in the North China Craton,extending in a northeast-southwest direction with an area of >350 km2.We carried out SHRIMP zircon dating,Hf-in-zircon isotopic analysis and a whole-rock geochemical study on igneous and metasedimentary rocks recovered from drill holes that penetrated into the basement of the CHB.Two samples of gneissic granodiorite(XG1-1) and gneissic quartz diorite(J48-1) have magmatic ages of 2500 and2496 Ma.respectively.Their zircons also record metamorphic ages of 2.41-2.51 and 2.5 Ga,respectively.Compared with the gneissic granodiorite,the gneissic quartz diorite has higher ∑REE contents and lower Eu/Eu* and(La/Yb)n values.Two metasedimentary samples(MG1,H5) mainly contain 2.5 Ga detrital zircons as well as late Paleoproterozoic metamorphic grains.The zircons of different origins haveεHf(2.5 Ga) values and Hf crustal model ages ranging from 0 to 5 and 2.7 to 2.9 Ga.respectively.Therefore,2.5 Ga magmatic and Paleoproterozoic metasedimentary rocks and late Neoarchean to early Paleoproterozoic and late Paleoproterozoic tectono-thermal events have been identified in the basement beneath the CHB.Based on regional comparisons,we conclude that the early Precambrian basement beneath the CHB is part of the North China Craton.Yusheng Wan Xianzheng Zhao Zejiu Wang Dunyi Liu Alfred Krner Chunyan Dong Hangqian Xie Yuansheng Geng Yuhai Zhang Runlong Fan Huiyi Sun 2014Geoscience Frontiers2014,5,4:3
10Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis.Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi 2021Journal of Clinical and Translational Hepatology2021,9,6:3
11The onset of deep recycling of supracrustal materials at the Paleo-Mesoarchean boundary显示文摘The recycling of supracrustal materials, and in particular hydrated rocks, has a profound impact on mantle composition and thus on the formation of continental crust, because water modifies the physical properties of lithological systems and the mechanisms of partial melting and fractional fractionation. On the modern Earth, plate tectonics offers an efficient mechanism for mass transport from the Earth’s surface to its interior, but how far this mechanism dates back in the Earth’s history is still uncertain. Here, we use zircon oxygen(O) isotopes to track recycling of supracrustal materials into the magma sources of early Archean igneous suites from the Kaapvaal Craton, southern Africa. The mean δ^(18)O values of zircon from TTG(tonalite–trondhjemite–granodiorite) rocks abruptly increase at the Paleo-Mesoarchean boundary(ca.3230 million years ago;Ma), from mantle zircon values of 5‰–6‰ to approaching 7.1‰, and this increase occurs in ≤3230 Ma rocks with elevated Dy/Yb ratios. The^(18)O enrichment is a unique signature of low-temperature water–rock interaction on the Earth’s surface. Because the later phase was emplaced into the same crustal level as the older one and TTG magmas would derive from melting processes in the garnet stability field(>40 km depth), we suggest that this evident shift in TTG zircon O isotopic compositions records the onset of recycling of the mafic oceanic crust that underwent seawater hydrothermal alteration at low temperature. The onset of the enhanced recycling of supracrustal materials may also have developed elsewhere in other Archean cratons and reflects a significant change in the tectonic realm during craton formation and stabilization, which may be important processes for the operation of plate tectonics on early Earth.Xiaolei Wang Ming Tang Jeff Moyen Di Wang Alfred Kröner Chris Hawkesworth Xiaoping Xia Hangqiang Xie Carl Anhaeusser Axel Hofmann Junyong Li Linsen Li 2022National Science Review2022,9,3:3
12Dispersive analysis for η → γγ ?显示文摘C. Hanhart A. Kup?? U.-G. Mei?ner F. Stollenwerk A. Wirzba 2013The European Physical Journal C2013,,12:2
13S3-Leitlinie Kolorektales Karzinom Version 1.0 - Juni 2013 AWMF-Registernummer: 021/007OL显示文摘C. Pox S. Aretz S. Bischoff U. Graeven M. Hass P. Heu?ner W. Hohenberger A. Holstege J. Hübner F. Kolligs M. Kreis P. Lux J. Ockenga R. Porschen S. Post N. Rahner A. Reinacher-Schick J. Riemann R. Sauer A. Sieg W. Scheppach W. Schmitt H. Schmoll K. Schulm 2013Z Gastroenterol2013,,08:2
14高速连铸用新型浸入式水口显示文摘连铸机结晶器内钢液的流动状态严重影响连铸坯的质量,尤其在弯月面处,钢液与结晶器保护渣直接接触,结晶器内弯月面不稳定引起的卷渣,是导致产品产生缺陷的主要原因之一,如冷轧薄板的线状缺陷和厚板的表面缺陷。在结晶器润滑不均匀时,还会增加漏钢危险。弯月面液面波动主要是由于浸入式水口吐出孔钢液剧烈的湍流和瞬态行为引起的。最近,在一台连铸机上浇注不同钢种已成为全世界钢铁生产商努力的一个主要方向。为了满足所有钢种的质量要求,对每个钢种都要求一定的浇注速度。对常规的浸入式水口而言,确保结晶器内有利的流动条件是一个难题。因此,比以往更需要一种新型浸入式水口,通过保持最佳的结晶器内钢液流动状态,以各种浇注速度浇注出多规格铸坯。介绍了测试新型浸入式水口流动性能的数值模型和物理模型的试验。采用URANS方法瞬态CFD模拟表明,新型浸入式水口流出的钢液瞬态行为稳定,因而弯月面以下钢液流速较慢,其效果还通过水模拟得到了验证。现场试验是在中国台湾的中钢公司进行的,试验结果表明,通过优化结晶器内钢液的流动行为,结晶器液面波动明显减小,从而提高了产品质量。Shung Sheng Kao Hsin Chin Kua Oliver Wiens Wolfgang Mo?ner Markus Reifferscheid Nobert Vogl Gernot Hackl Gerald Nitzl 潘秀兰 2014世界钢铁2014,,1:2
15Dynamics of behavior: Theory and applications for autonomous robot architectures显示文摘G. Sch?ner M. Dose C. Engels 1995Robotics and Autonomous Systems1995,,2:2
16Annual cycle of ni- trogen removal by a pilot-scale subsurface horizontal flow in a constructed wetland under moderate climate 显示文摘Kuschk P Winβner A Kappelmeyer U 2003Water Research2003,37,17:1
17The Management of Appendiceal Mass in Children: Is Interval Appendectomy Necessary?显示文摘?rfan Karaca Zekai Alt?ntoprak Ayta? Kark?ner Günyüz Temir Erol Mir 2001Surgery Today2001,,8:1
18FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C显示文摘Heeg MH Ulsenheimer A Grü ner NH 0,,4:1
19Retinopathy is reduced during experimental di- abetes in a mouse model of outer retinal degeneration 显示文摘de Gooyer TE Stevenson KA Htmlphries P Simpson DA Gardi- ner TA Stitt AW 2006In- vest Ophthalmol Vis Sci2006,47,12:1
20In vivo action of corticosteroids on the guinea pig lens显示文摘Friedburg D Krǒner H Rosenstiel L 1974Ophthalmic Res1974,6,3:1
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