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| 1 | MicroRNAs:a new ray of hope for diabetes mellitus显示文摘Diabetes mellitus has become one of the most common chronic diseases,thereby posing a major challenge to global health.Characterized by high levels of blood glucose(hyperglycemia),diabetes usually results from a loss of insulin-producing β-cells in the pancreas,leading to a deficiency of insulin(type 1 diabetes),or loss of insulin sensitivity(type 2 diabetes).Both types of diabetes have serious secondary complications,such as microvascular abnormalities,cardiovascular dysfunction,and kidney failure.Various complex factors,such as genetic and environmental factors,are associated with the pathophysiology of diabetes.Over the past two decades,the role of small,single-stranded noncoding microRNAs in various metabolic disorders,especially diabetes mellitus and its complications,has gained widespread attention in the scientific community.Discovered first as an endogenous regulator of development in the nematode Caenorhabditis elegans,these small RNAs post-transcriptionally suppress mRNA target expression.In this review,we discuss the potential roles of different microRNAs in diabetes and diabetes-related complications. | Munish Kumar Sayantan Nath Himanshu K Prasad G D Sharma Yong Li | 2012 | Protein & Cell2012，3，10： | 14 |
| 2 | In-vitro scolicidal activity of Mallotus philippinensis (Lam.) Muell Arg. fruit glandular hair extract against hydatid cyst Echinococcus granulosus显示文摘Objective: To investigate new scolicidal agent from natural resources to cope with the side effects associated with synthetic drugs in Echinococcosis. Methods: The scolicidal potential of methanolic fruit powder extract (10 and 20 mg/mL) of Mallotus philippinensis ( M. philippinensis ) was investigated. Viability of protoscoleces was confirmed by trypan blue exclusion method, where mortality was observed at concentration of 10 and 20 mg/mL in 60 min treatment against Echinococcus granulosus ( E. granulosus ), under in-vitro conditions with reference to the known standard drug Praziquantel . Results: At concentration 10 and 20 mg/mL, the mortality rate was observed 97% and 99% respectively for 60 min treatment; while up to 93% mortality was observed with 20 mg/mL for only 10 min treatment. The concentration above 20 mg/mL for above 2 h showed 100% mortality, irrespective of further incubation. Conclusions: As compared with the standard anti-parasitic drug Praziquantel our extract has significant scolicidal activity with almost no associated side effects. | Mayank Gangwar Vijay C Verma Tryambak D Singh Sushil K Singh RK Goel Gopal Nath | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，8： | 3 |
| 3 | Coating copper on graphite fibers显示文摘 | Rohatgi P K Nath D Shi Z Y | 1991 | Acta Metallurgica Sinica1991，82，10： | 1 |
| 4 | DV based positioning in Ad Hoc net- works显示文摘 | NICULESCU D NATH B | 2003 | Journal of Telecommunication Systems2003，22，1234： | 1 |
| 5 | 查看详情显示文摘 | Nath D C D Bandyopadhyay S Boughton P Yu A | | 0，，： | 1 |
| 6 | Ad-Hoc PositioningSystem(APS)显示文摘 | D Niculescu’B Nath | 2001 | IEEE Global Telecommunications2001，5，06： | 1 |
| 7 | Ad-Hoc positioning system 显示文摘 | Niculescu D Nath B | 2001 | In IEEE GlobeCom2001，11，6： | 1 |
| 8 | DV based positioning in ad hoc networks显示文摘 | Niculescu D Nath B | 2003 | Journal of Telecommunication Systems2003，22，4： | 1 |
| 9 | Twisted charge transfer process of nile red in homogeneous solution and in faujasite zeolite显示文摘 | Sarkar N Das K Nath D N | 1994 | Langmuir1994，10，1： | 1 |
| 10 | DV Based Positioning in Ad hoc Networks显示文摘 | Niculescu D Nath B | 2003 | Journal of Telecommunication Systems2003，21，： | 1 |
| 11 | DV based positioning in ad hoc networks 显示文摘 | Niculescu D Nath B | 2003 | Journal of Telecommunication Systems2003，22，14： | 1 |
| 12 | Effects of interfi- her spacing and matrix cracks on stress amplification factors in carbon fiber/epoxy matrix composites part 2:Hexagonal array of fiber显示文摘 | Sirivedin S Fenner D N Nath R B | 2006 | Composites A2006，37，11： | 1 |
| 13 | DV-based positioning in Ad Hoc Networks 显示文摘 | Niculescu D Nath B | 2003 | Journal of Telecommunication Systems2003，22，14： | 1 |
| 14 | Synthesis and antimierobial activity of Schiff and Mannich bases of i- satin and its derivatives with pyrimidine 显示文摘 | Pandeya S N Sriram D Nath G | 1999 | Farmaco1999，4，9： | 1 |
| 15 | Disruption of neurogenesis in the subventricular zone of adult mice,and in human cortical neuronal precursor cells in culture,by amyloid beta-peptide:implications for the pathogenesis of Alzheimer's disease显示文摘 | Haughey NJ Liu D Nath A | 2002 | Neuromolecular Med2002，1，2： | 1 |
| 16 | Disruption of neurogenesis by amyloid β-peptide and perturbed calcium homeostasis in models of Alzheimer's disease 显示文摘 | Haughey N J Nath A Liu D | 2002 | J Neuroehem2002，83，： | 1 |
| 17 | An electronically tunable microstrip bandpass filter using thin-film Bafium-Strontium-Titanate (BST) varactors 显示文摘 | Nath J Ghosh D Mafia J-P | 2005 | IEEE Trans Microw Theory Techn2005，53，9： | 1 |
| 18 | 查看详情显示文摘 | Nath D C D Bandyopadhyay S Yu A | | 0，，： | 1 |
| 19 | Treatment with antisense oligonucleotide reduces the expression of type I collagen in a human-skin organ-wound model:implications for antifibrotic gene therapy显示文摘 | XIONG W HUMPHRIES A D | 2007 | Ann Plast Surg2007，59，6： | 1 |
| 20 | Ad-hoc positioning system(APS)显示文摘 | Niculescu D Nath B | 2001 | IEEE Communication Society2001，7，5： | 1 |
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