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| 1 | 丝胶蛋白及其酶解产物的保湿与抗氧化和抑制酪氨酸酶活性分析显示文摘从蚕茧中提取丝胶蛋白并酶解为丝胶蛋白肽,考察丝胶蛋白与不同分子质量丝胶蛋白肽的保湿性能以及对1,1-二苯基-2-三硝基苯肼(DPPH)自由基的清除能力和对酪氨酸酶活性的抑制作用,为高效、合理开发利用丝胶蛋白资源提供基础依据。结果表明:0~14h内,质量分数为5%、10%和15%的丝胶蛋白肽的保湿性能可与相同质量分数的甘油相媲美,保湿时间较长,分子质量较大的丝胶蛋白肽溶液的保湿性能也较优;丝胶蛋白及不同分子质量的丝胶蛋白肽均有一定的清除DPPH自由基和抑制酪氨酸酶活性的能力,尤以分子质量较小的丝胶蛋白肽的清除与抑制能力相对较强,同一种分子质量的丝胶蛋白肽,其清除DPPH自由基的能力和抑制酪氨酸酶活性的能力则呈现明显的量效关系。生产上可以根据丝胶蛋白的用途制备不同分子质量的丝胶蛋白酶解产物。 | 靳春平 张海萍 杨明英 NAMITA Mandal 朱良均 | 2013 | 蚕业科学2013，39，6： | 9 |
| 2 | Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis显示文摘Periodontitis 是 periodontium 的煽动性的疾病。在 neutrophils 和织物禁止者分泌的矩阵 metalloproteinases (MMP ) 之间的任何不平衡在口香糖织物开始骨胶原的破坏,导致长期的 periodontitis。这研究瞄准了 MMP-8 的唾液的层次和长期的 periodontitis 的牙齿周围的参数到相互关联为长期的 periodontitis 的早诊断作为一个 noninvasive 标记建立 MMP-8。学习包含了访问扎乌丁·阿赫马德博士的 periodontic OPD 的 40 个题目牙齿的学院和医院,在 Aligarh 定位了, U.P,印度,从 2011 ~ 2012。这些题目被划分成二个组:组当组 II 与长期的 periodontitis 由 20 个病人组成了时,我由 20 个牙齿周围地健康的题目(控制) 组成了。长期的 periodontitis 根据几个牙齿周围的参数被估计,包括探查深度(PPD ) 的衣袋,临床的附件水平(CAL ) ,齿龈的索引(官方补给) ,并且匾索引(PI ) 。为由用 Quantikine 人总数 MMP-8 免疫分析工具包的 ELISA 的 MMP-8 评价在 unstimulated 和整个吐的口水的 3ml 附近是镇定的。数据用 STATISTICA (Windows 版本 6 ) 软件被分析。组的唾液的 MMP-8 层次我和 II 是 190.91?? | Namita Gupta N.D. Gupta Akash Gupta Saif Khan Neha Bansa | 2015 | Frontiers of Medicine2015，9，1： | 5 |
| 3 | Targeting cancer testis antigens for biomarkers and immunotherapy in colorectal cancer: Current status and challenges显示文摘Colorectal cancer ranks third among the estimatedcancer cases and cancer related mortalities in United States in 2014. Early detection and efficient therapy remains a significant clinical challenge for this disease. Therefore, there is a need to identify novel tumor asso-ciated molecules to target for biomarker development and immunotherapy. In this regard, cancer testis antigens have emerged as a potential targets for developing novel clinical biomarkers and immunotherapy for various malignancies. These germ cell specific proteins exhibit aberrant expression in cancer cells and contribute in tumorigenesis. Owing to their unique expression profile and immunogenicity in cancer patients, cancer testis antigens are clinically referred as the most promising tumor associated antigens. Several cancer testis antigens have been studied in colorectal cancer but none of them could be used in clinical practice. This review is an attempt to address the promising cancer testis antigens in colorectal cancer and their possible clinical implications as biomarkers and immunotherapeutic targets with particular focus on challenges and future interventions. | Anil Suri Nirmala Jagadish Shikha Saini Namita Gupta | 2015 | World Journal of Gastrointestinal Oncology2015，7，12： | 4 |
| 4 | Effect of Low Level Subchronic Microwave Radiation on Rat Brain显示文摘Objective The present study was designed to investigate the effects of subchronic low level microwave radiation(MWR) on cognitive function,heat shock protein 70(HSP70) level and DNA damage in brain of Fischer rats.Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900,1800,and 2450 MHz.Animals were divided into 4 groups: Group I: Sham exposed,Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate(SAR) 5.953 × 10-4 W/kg,Group III: animals exposed to 1800 MHz at SAR 5.835 × 10-4 W/kg and Group IV: animals exposed to 2450 MHz at SAR 6.672 × 10-4 W/kg.All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues.HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay.Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function,increase in HSP70 level and DNA damage in brain.Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900,1800,and 2450 MHz may lead to hazardous effects on brain. | Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta | 2016 | Biomedical and Environmental Sciences2016，29，12： | 4 |
| 5 | 丝素蛋白生物材料在骨修复中的应用研究进展显示文摘丝素蛋白是一种具有良好机械性能的天然高分子纤维蛋白,由于其优异的生物相容性、降解产物无毒性和低免疫原性等特点,被广泛用于骨修复生物材料的研发。本文综述国内外学者以不同形式的丝素蛋白生物材料应用于骨修复的研究成果,包括丝素膜、丝素纳米纤维、丝素水凝胶、丝素多孔支架等。这些丝素蛋白生物材料可以经过适当的化学修饰以及负载生长因子和复合无机物等,使其在体外具有促进成骨细胞增殖分化的功能,在体内具有诱导新骨形成的功能。 | 施李杨 杨明英 NAMITA Mandal浙江大学动物科学学院 朱良均 | 2013 | 蚕业科学2013，39，4： | 3 |
| 6 | Phytochemical, Anti-oxidant, Larvicidal, and Antimicrobial Activities of Castor(Ricinus communis) Synthesized Silver Nanoparticles显示文摘Objective Castor possesses the medicinal properties. Hence, castor extract has the reducing power agent was used in nanoparticles synthesis. Extract of castor also produces secondary metabolites(phenolics, reducing agent) and exhibits anti-oxidant property, which was used as larvicide and antimicrobial agent. In the present study the silver nanoparticles(Ag NPs) were synthesized using aqueous leaf extract of castor. Methods The synthesized Ag NPs were characterized with UV-visible spectroscopy and transmission electron microscopy(TEM). The phenolics, reducing sugar and total sugar were evaluated performing Folin-Ciocalteu reagent method, DNS method and Phenol-sulphuric acid method. Anti-oxidant activity of synthesized nanoparticles was evaluated using DPPH assay. The larvicidal activity of synthesized Ag NPs was evaluated against the third instar of Anopheles stephensi and Aedes aegypti. The mortality was observed after 24 h by probit analysis. Further, the antimicrobial activity was reported against Staphylococcus aureus(Gram positive) and Pseudomonas aeruginosa(Gram negative). Results The UV spectra showed maximum absorbance at 445 nm and TEM analysis indicated spherical shape of nanoparticles with average size of 8.96 nm. The synthesized nanoparticles also possessed anti-oxidant potentials. Thus, it could be used as potential free radical scavenger. The larvae of A. stephensi were found more susceptible to Ag NPs than larvae of A. aegypti. Conclusion Due to the medicinal properties and reducing power activity, in the present study Ag NPs have been synthesized using the aqueous leaves extract of castor and access their phytochemical, anti-oxidant, larvicidal and antimicrobial properties. | Namita Soni Ramesh C.Dhiman | 2017 | Chinese Herbal Medicines2017，9，3： | 3 |
| 7 | 预矿化丝素/壳聚糖复合支架的表征及细胞相容性显示文摘以丝素和壳聚糖为原料,采用冷冻干燥法制备丝素/壳聚糖支架,通过预矿化使羟基磷灰石(HA)沉积,形成多孔羟基磷灰石-丝素蛋白/壳聚糖复合支架。对复合支架进行红外吸收光谱(FT-IR)、X射线衍射(XRD)、扫描电子显微镜(SEM)、热重分析(TGA)、力学性能和空隙率表征;采用WST-1方法检测MG-63骨肉瘤细胞在复合支架上的增殖情况,评价其细胞相容性。结果显示,沉积的HA结构属于弱结晶态范畴,主要位于孔壁上,且随着预矿化循环次数的增加,沉积量增多,使预矿化复合支架的弹性模量得到极显著的提高,其孔隙率保持在90%左右的较高水平;WST-1检测表明,含有HA的预矿化复合支架对细胞增殖有明显的促进作用,具有良好的细胞相容性。 | 施李杨 邓连霞 杨明英 张海萍 Mandal Namita 朱良均 | 2013 | 高分子材料科学与工程2013，29，11： | 2 |
| 8 | 利用尿素溶剂体系制备再生柞蚕丝素蛋白粉及样品的性能表征显示文摘针对柞蚕丝素纤维很难溶于一般溶剂的特点,并考虑生产成本及环保因素,开发了2种含8 mol/L尿素(urea)的碱性溶剂体系Urea/NaOH与Urea/LiOH用于制备再生柞蚕丝素蛋白粉末,以利于柞蚕丝素蛋白在生物医学材料领域的应用。对采用不同尿素溶剂体系制备的再生柞蚕丝素蛋白样品进行氨基酸组成分析与红外光谱(FTIR)、核磁共振谱(NMR)和热力学性能表征,结果显示常温下柞蚕丝素纤维在2种溶剂体系中均被溶解,且伴随有分解现象,其中在Urea/NaOH溶剂体系中的分解发生在非结晶区,在Urea/LiOH溶剂体系中结晶区和非结晶区均可发生分解。生产上可以依据制备再生柞蚕丝素蛋白的用途,选择不同的尿素溶剂体系。 | Namita Mandal 周官山 帅亚俊 何文 闵思佳 杨明英 朱良均 | 2013 | 蚕业科学2013，39，2： | 2 |
| 9 | Mechanisms of adhesion of Paenibacillus polymyxa onto hematite, corundum and quartz显示文摘 | NAMITA D NATARAJAN K A SOMASUNDARAN P | 2001 | Mineral Processing2001，62，7： | 1 |
| 10 | Practical formulas forestimation of cable tension by vibration method显示文摘 | Zui H Shinke T Namita Y | 1996 | Journal of Structural Engineering1996，122，6： | 1 |
| 11 | Practical formulas for esti- mation of cable tension by vibration method 显示文摘 | ZUI H SHINKE T NAMITA Y | 1996 | Journal of Structural Engineering1996，122，6： | 1 |
| 12 | Practical formulas for estimation of cable tension by vibration method显示文摘 | Zui H Shinke T Namita Y | 1996 | Journal of Structural Engineering ASCE1996，122，6： | 1 |
| 13 | Mechanical behaviour of function alised nanotubes 显示文摘 | S Namitae N Chandra C Shet | 2004 | Chemical Physics Letters2004，387，： | 1 |
| 14 | Practical formulas for estimationof cable tension by vibration method 显示文摘 | Zui H Shinke T Namita Y | 1996 | Journal of StructuralEngineering ASCE1996，122，6： | 1 |
| 15 | Biodegradation of some organic flotation reagents by bacillus polymyxa 显示文摘 | Namita Deo Natarajan K A | 1998 | Bioremediation Journal1998，18，2： | 1 |
| 16 | Practical formulas for estimation cable tension by vibration method 显示文摘 | Zui H Shinke T Namita Y | 1996 | ASCE Journal of Structural Engineering1996，122，6： | 1 |
| 17 | Calcium and phosphate regulation of nitrogen metabolism in the cyanobacterium Spirulina platensis under the high light Stress显示文摘 | Singh D P Singh Namita | 2000 | Current Microbiology2000，41，： | 1 |
| 18 | Practical formulas for estimation of cable tension by vibration method显示文摘 | Zui H Shinke T Namita Y | 1996 | Journal of Structural Engineering1996，122，6： | 1 |
| 19 | Practical formulas for estimation of cable tension by vibration method 显示文摘 | Z H SHINKE T NAMITA Y | 1996 | Journal of Structural Engineering ASCE1996，122，6： | 1 |
| 20 | Practical Formulas for Estimation of Cable Tension by Vibration Method 显示文摘 | Hiroshi Zui Tohru Shinke Yoshio Namita | 1996 | Joumal of Structural Engineering ASCE1996，122，6： | 1 |
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