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2篇 您的检索式:作者名="N.Savitri Kumar"
    题名 作者 年代 出处 被引量
1Secondary Metabolites Produced by an Endophytic Fungus Pestalotiopsis microspora显示文摘An endophytic fungus Pestalotiopsis microspora isolated from the fruits of Manilkara zapota was cultured in potato dextrose broth media.Chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of a new azaphilonoid named pitholide E(1),in addition to previously identified pitholide B(2),pitholide D(3),pestalotin(LL-P880α)(4),PC-2(5),LL-P880β(6),tyrosol(7)and 4-oxo-4H-pyran-3-acetic acid(8).An endophytic fungus P.microspora from M.zapota and the isolation of compounds 1-5,7 and 8 from P.microspora are reported here for the first time.G.R.Nalin Rathnayake N.Savitri Kumar Lalith Jayasinghe Hiroshi Araya Yoshinori Fujimoto 2019Natural Products and Bioprospecting2019,9,6:4
2Secondary metabolites from an endophytic fungus Aspergillus fumigatus from Solanum insanum L.显示文摘An endophytic fungus Aspergillus fumigatus,isolated from the fruits of Solanum insanum L.,was cultured in potato dextrose broth medium.Chromatographic separation of the EtOAc extract led to the isolation of six secondary metabolites,identified as pseurotin A(1),fumigaclavine C(2),monomethylsulochrin(3),trypacidin(4),fumiquinazoline C(5)and guignasulfide(6)by spectral means.Compounds 2 and 3 showed brine shrimp toxicity with IC50 values of 147 and 74.2μM,respectively,while compounds 4 and 5 showed slight inhibition on the growth of fungal pathogen Cladosporium cladosporioides.This is the first report of the isolation of guignasulfide(6)from A.fumigatus,which has been previously isolated only from an endophytic fungus Guignardia sp.Vindya Kanthi Munasinghe N.Savitri Kumar Nimal Adikaram Lalith Jayasinghe Hiroshi Araya Yoshinori Fujimoto 2021Asian Journal of Traditional Medicines2021,16,2:0
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