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您的检索式：作者名="Musial Frauke"
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| 1 | Placebo responses in patients with gastrointestinal disorders显示文摘Over the last several years there has been a growing interest in placebo, not only as an inert control in clinical trials, but also in the placebo effect as a group effect as well as a reaction in individual subjects. Methodological factors such as regression to the mean and natural history of the disease play a role in the evaluation of a possible placebo effect. In this report, we discuss several factors including Pavlovian conditioning, beliefs outcome, expectations, and other factors as potential mediators of the placebo response. Placebo effects are common in gastrointestinal diseases and there seems to be no clear difference between placebo effects in functional gastrointestinal diseases (functional dyspepsia and irritable bowel syndrome) and organic gastrointestinal disease (duodenal ulcer and inflammatory bowel disease). | Frauke Musial Sibylle Klosterhalfen Paul Enck | 2007 | World Journal of Gastroenterology2007，13，25： | 7 |
| 2 | Menopause in German and Chinese Women——An Analysis of Symptoms,TCM-diagnosis and Hormone Status显示文摘目的将在上海(中国) 调查经绝期相关的症状,繁体中文药(TCM ) 诊断和绝经女人,在 Essen (德国) 的女人和其它的二件可比较的城市的样品的荷尔蒙地位。受不了经绝期症候群的方法病人在德国(35 个题目) 从 Duisburg-Essen 的大学的 TCM 门诊病人诊所被招募,从 Shuguang,医院在中国(35 个题目) 结盟了到繁体中文药的上海大学。为跟踪绝经症状的 Kupperman 索引被使用。完全的 TCM 诊断被一样的调查者在中国以及在德国执行。睾丸激素和雌激素血样品从每个女人被收集一次。在那里的结果是在 Kupperman 索引的特定的症状的有效差量,例如在德国绝经女人的蚁走感和消沉的更高的流行;而中国绝经女人从眩晕,头疼和同等感觉症状更显著地受苦了。有关 TCM 诊断,沈(肾)-yang 缺乏与中国女人的 5.71 % 相对照在 51.43% 德国女人被诊断;德国女人的 17.14 % 作为与中国女人的 74.29 % 相比有 Shen-yin 缺乏被诊断。德国女人与中国女人(P⩽0.0005 ) 相比为睾丸激素显示出显著地更低的吝啬的荷尔蒙层次。结论德国、中国的绝经女人不显示出不同流行,但是有绝经症状的不同模式。从一个 TCM 观点,而中国女人从 Shen-yin 缺乏症候群承受更多,而且,德国女人从沈阳缺乏承受更多。这些结果被支持由显著地在与中国女人相比的德国女人的睾丸激素的底层,在 TCM,它是 yang 的一个特征缺乏。 | Rampp Thomas Tan Linda ZHANG Lin SUN Zhuo-jun Klose Petra Musial Frauke Dobos Gustav Juergen | 2008 | Chinese Journal of Integrative Medicine2008，14，3： | 3 |
| 3 | Do patients with gastroesophageal reflux disease and somatoform tendencies benefit from antireflux surgery?显示文摘BACKGROUND The clinical presentation of gastroesophageal reflux disease(GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in the symptomatic spectrum between proven GERD and other disorders such as dyspepsia, functional heartburn and/or somatoform disorders.AIM To prospectively evaluate the GERD patients with and without somatoform disorders before and after laparoscopic antireflux surgery.METHODS In a tertiary referral center for foregut surgery over a period of 3 years patients with GERD, qualifying for the indication of laparoscopic antireflux surgery, were investigated prospectively regarding their symptomatic spectrum in order to identify GERD and associated somatoform disorders. Assessment of symptoms was performed by an instrument for the evaluation of somatoform disorders[Somatoform Symptom Index(SSI) > 17]. Quality of life was evaluated by Gastrointestinal Quality of Life Index(GIQLI).RESULTS In 123 patients an indication for laparoscopic antireflux surgery was established and in 43 patients further medical therapy was suggested. The portion of somatoform tendencies in the total patient population was 20.48%(34 patients).Patients with a positive SSI had a preoperative GIQLI of 77(32-111). Patients with a normal SSI had a GIQLI of 105(29-140)(P < 0.0001). In patients with GERD the quality of life could be normalized from preoperative reduced values of GIQLI102(47-140) to postoperative values of 117(44-144). In patients with GERD and somatoform disorders, the GIQLI was improved from preoperative GIQLI 75(47-111) to postoperative 95(44-122)(P < 0.0043).CONCLUSION Patients with GERD and associated somatoform disorders have significantly worse levels of quality of life. The latter patients can also benefit from laparoscopic fundoplication, however they will not reach a normal level. | Hans Friedrich Fuchs Benjamin Babic Karl-Hermann Fuchs Wolfram Breithaupt Gabor Varga Frauke Musial | 2019 | World Journal of Gastroenterology2019，25，3： | 1 |
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