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您的检索式：作者名="Musayev Seymur"
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| 1 | Efficiency of Esmolol in Treating Postoperative Arterial Hypertension in Patients with Ischemic Heart Disease显示文摘To investigate the efficiency and safety of(β+α)-adrenoblocker esmolol for postoperative arterial hypertention(PAH)in patients with ischemic heart disease.The study included 25 patients(45-65 years,mean age 51.5±7.3)who underwent coronary artery bypass grafting surgery with continuous blood purification(CPB).PAH developed during first post-op hours,all patients were ventilated with 2-4 scale sedation by RASS.All patients had arterial hypertension and were on constant therapy.Esmolol was administered IV push 20 mg within a minute.When required,injection was repeated in 5 min until full required effect.Maximum dose was 100 mg.For intraoperative treatment of hypertension 80 mg bolus within 30 sec was injected followed by 150 mg/kg/min infusion when required.Post-op dosage was administered similarly.Esmolol treatment was efficient in 82.6%of cases.Most frequent target AH was achieved using up to 40 and 60 mg in 20%and 36.9%of cases accordingly.Antihypertension effect maintained within 24 hours after injection.Esmolol cause moderate reduction of heart rate(4-7%),making it possible to use in case of hypertension without tachycardia.It is well tolerated and safe as no side effects were observed.The study showed high efficiency and safety of using esmolol to manage post-op arterial hypertension in cardiac surgery patients. | Abbasov Fazil Mahmudov Reshad Musayev Seymur Kurbanov Emil Isayeva Aynur | 2021 | Journal of Pharmacy and Pharmacology2021，9，4： | 0 |
| 2 | Features of Management of Patients Undergoing Coronary Artery Bypass Grafting in the Early Postoperative Period显示文摘Objectives:Coronary heart disease(CHD)is a leading cause of death and disability worldwide.Coronary artery bypass graft(CABG)is the most performed surgical procedure to treat coronary heart disease.Along with the standard medical treatment,the rehabilitation program and exercise activities should be implemented in the treatment process to avoid adverse preoperative events.Methods:Of the 132 patients,30 patients received isolated CABG,30 patients-mitral valve prosthesis,and 72 patients underwent concomitant CABG+mitral valve surgery.The common drug treatments after CABG were aspirin,clopidogrel,beta-blockers,angiotensin-converting enzyme(ACE)inhibitors,statins.The rehabilitation program,including physical and psychological therapy,was initiated from the first postoperative day and continued throughout the hospital stay.Results:The duration of physical therapy was a course of 10-12 days with a further transition to the next stage of rehabilitation treatment.Of the 132 operated patients,only 37(28%)had an adequate mental state.The remaining 95(72%)patients had significant mental changes including neurosis(20 cases),anxiety-depressive state(49 cases),hypochondria(19 cases),hysteria(7 cases).Through the individual approach and medical treatment,121(91.7%)patients had an adequate mental state on days 12-14 postoperatively.The mortality was in 8.3%(11patients).Conclusions:The implementation of rehabilitation programs including physical and psychological therapy accelerates convalescence periodand return to normal life of early post-CABG patients. | Musayev Seymur Aydin | 2021 | Journal of Pharmacy and Pharmacology2021，9，11： | 0 |
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