|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 2 | Purification and Characterisation of a Coffee Pulp Tannase Produced by Penicillium verrucosum显示文摘 | Roopali N. Bhoite Navya P. N Pushpa S. Murthy | 2013 | Journal of Food Science and Engineering2013，3，6： | 2 |
| 3 | Study of two component systems with failure interactions显示文摘 | Murthy D N P Nguyen D G | 1985 | Naval Research Logistics Quarterly1985，32，： | 1 |
| 4 | Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging显示文摘 | Hamblin MR O'Donnell DA Murthy N | 2002 | Pbotochem Photobiol2002，75，1： | 1 |
| 5 | Segmentation of fingerprint images using the directional images 显示文摘 | Mehtre B M Murthy N N Kapoor S | 1987 | Pattern Recognition1987，20，4： | 1 |
| 6 | Studies on the leaf chemistry and quality of agency burley tobacco 显示文摘 | Murthy K S N Muralidhar G Walker E K | 1989 | Tob Res1989，15，2： | 1 |
| 7 | Spectrophotometric Determination of Flutamide, Nimesulide and Meloxicam显示文摘 | Murthy T K Reddy M N Reddy M D | 2001 | Asian J Chem2001，13，3： | 1 |
| 8 | The six minute walk test accurately estimates mean peak oxy- gen uptake显示文摘 | ROSS R M MURTHY J N WOLLAK I D | 2010 | BMC Pulm Med2010，10，31： | 1 |
| 9 | Clinico- pathologic study of dextran sulfate sodium experimental mu- rine colitis显示文摘 | COPPER H S MURTHY S N SHAH R S | 1993 | Lab Invest1993，69，： | 1 |
| 10 | Effects of light emitting diodes on the in vitro induction and growth of bulhlets of Liliurn oriental hybrid Pesaro 显示文摘 | Lian M L Murthy H N Pack K Y | 2002 | Scientia Horticulturae2002，94，3： | 1 |
| 11 | Acid-degradable particlesfor protein-based vaccines:Enhanced survival rate fortumor-challenged mice using ovalbumin model显示文摘 | Standley SM Kwon Y J Murthy N | 2004 | Bioconjugate Chemistry2004，15，6： | 1 |
| 12 | Comments on“Maintenance Policies with Two-Dimensional Warranty”显示文摘 | Jack N Murthy D N P Iskandar B P | 2003 | Reliability Engineering&System Safety2003，82，1： | 1 |
| 13 | Crystalline constitutents of Fluggea microcarpa Blume显示文摘 | JAIRAI M A | 1988 | J Ind Chem Soc1988，65，： | 1 |
| 14 | Catalytic Vapor Phase Reduction of Nitrobenzene to Aniline in Fluidized Beds显示文摘 | Deshpande P K Kuloor N R | 1963 | Chemical Age of India1963，14，： | 1 |
| 15 | Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants显示文摘 | Kaler E W Murthy A K Zasadzinski A N | 1989 | Science1989，245，4924： | 1 |
| 16 | pH-sensitive polymers that enhance intracellular drug delivery in vivo显示文摘 | Kyriakides T R Cheung C Y Murthy N | 2002 | J Control Release2002，78，13： | 1 |
| 17 | Posterior corneal topographic changes after retreat me nt LASIK显示文摘 | Rani A Murthy BR Sharma N | 2002 | Ophthalmology2002，109，11： | 1 |
| 18 | Mass multiplication of protocorm-like bodies using bioreactor system and subsequent plant regeneration in Phalaenopsis 显示文摘 | Young P S Murthy H N Pack K Y | 2000 | Plant Cell2000，63，1： | 1 |
| 19 | A flexible extended warranty and related optimal strategies显示文摘 | Jack N Murthy D N P | 2007 | The Journal of the Operational Research Society2007，58，12： | 1 |
| 20 | 查看详情显示文摘 | Murthy S. N Madhav B Reddy V. P | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员