|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 尿激酶治疗急性心肌梗塞多中心临床试验1406例总结显示文摘为观察尿激酶天普洛欣(UKTP)经静脉溶栓治疗急性心肌梗塞(AMI)的临床有效性及安全性。收集协作组148家医院1994年11月至1996年4月经静脉UKTP溶栓治疗AMI患者1406例,观察临床疗效、副作用及病死率等。其中124例行90分钟冠状动脉造影评价梗塞血管开通情况。结果:梗塞血管临床再灌注率为73.5%,90分钟冠状动脉造影血管开通率为72.6%,5周总病死率为7.8%(109/1406),轻度出血10.2%(143/1406),中重度出血0.43%(6/1406),脑出血0.50%(7/1406)。老年(>65岁)甚至高龄(>75岁)患者溶栓及距发病超过6小时者,其用药仍然安全有效,UKTP合适的用药剂量可能为150万U左右。结果提示UKTP治疗AMI安全有效。 | The collaborative study group for national multicenter clinical trial of urokinase thrombolytic therapy (Correspondence: Hu Dayi, Xu Zhimin. Beijing Red Cross Chao Yao Hospital, Beijing 100020) | 1997 | 中华心血管病杂志1997，25，3： | 139 |
| 2 | 微粒化非诺贝特治疗高脂血症疗效和耐受性显示文摘上海市多中心、开放性、自身比较,观察微粒化非诺贝特200mg,每晚一次,治疗131例高脂血症病人4~8周的疗效和耐受性。男性76例,女性55例,平均年龄56.2±9.73岁,所属高血脂类型:Ⅱa型26例,Ⅱb型53例,Ⅳ型52例。治疗8周之后,Ⅱa和Ⅱb型患者血清总胆固醇明显降低(平均降低20%,P<0.01),Ⅱb和Ⅳ型患者血清甘油三酯明显降低(平均降低60%~63%,P<0.01),未出现严重不良反应,结论:微粒化非诺贝特特别适用于治疗Ⅱb和Ⅳ型高脂血症患者。4例合并有高尿酸血症者,治疗8周后,血尿酸平均降低59%。 | Zhu Junren, Han Qingqin. Zhongshan Hospital, Shanghai Medical University, Shanghai 100032 Shanghai multicenter clinical study group ) | 1997 | 中华心血管病杂志1997，25，3： | 16 |
| 3 | Sodium oxybate demonstrates long term efficacy for the treatment of cataplexy in patients with narcolepsy显示文摘 | US Xyrem Multicenter Study Group | 2004 | Sleep Med2004，5，： | 1 |
| 4 | Randomized controlled trial of streptokinase,aspirin,and combination of both in treatmeat of acute ischemic stroke显示文摘 | | 1995 | Lancet1995，346，： | 1 |
| 5 | Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infections in the intensive care unit显示文摘 | Verwaest C Belgian Multicenter Study Group | 2000 | Clin Microbiol Infect2000，6，6： | 1 |
| 6 | Thrombolytic therapy with streptokinase in acute ischemic stroke 显示文摘 | The Multicenter Acute Stroke Trial-Europe Study Group | 1996 | N Engl J Med1996，335，： | 1 |
| 7 | Em-ergence of Nonencapsulated and Encapsulated Non-b-Type Invasive Haemophilus influenzae Isolates in Portugal (1989-2001)显示文摘 | BAJANCA P CANICA M the Multicenter Study Group | 2004 | J Clin Microb2004，42，2： | 1 |
| 8 | The Italian Group for Antiemetic Research in Radiotherapy显示文摘 | Radiation-induced emesis:a prospective observational multicenter Italian trial | 1999 | Int J Radiat Oncol Biol Phys1999，44，3： | 1 |
| 9 | Risk stratification and survival after myocardial infarction显示文摘 | Multicenter Pestinfarction Research Group | 1983 | N Engl J Med1983，309，6： | 1 |
| 10 | III Inpatients with Schizophrenia or Schizoaffecfive Disorder' 显示文摘 | Simpson GeorgeM 'Randomized Controlled Double-Blind Multicenter Comparison of the Efficacy and Tolerability of Ziprasidone and Olanzapine in Acutely | 2004 | American Jourual of Psychiatry2004，161，10： | 1 |
| 11 | Rando- mised trial comparing tacrolimus (FKS06) and cyclospo- fin in prevention of liver allograft rejection显示文摘 | European FK506 Multicenter Liver Study Group | 1994 | Lancet1994，344，8920： | 1 |
| 12 | Effect of implantable defibrillators on arrhyth mic events and mortality in the muhicenter unsus tained tachycardia trial 显示文摘 | Multicenter unsustained tachycardia trial investiga tors | 2002 | Circulation2002，106，： | 1 |
| 13 | Efficacy of metformin in patients with non-insulin Vdependent diabetes mellitns显示文摘 | DeFronzo RA Goodman AM Multicenter Metformin Study Group | 1995 | N Engl J Med1995，333，9： | 1 |
| 14 | Thrombolytic therapy with streptokinase in acute ischemic stroke, 显示文摘 | The Multicenter Acute Stroke Trial- Europe Study Group | 1996 | N Erigl J Med1996，335，3： | 1 |
| 15 | Randomised controlled trial of streptokinase aspirin and combination of both intreatment of acute ischemic stroke 显示文摘 | The Multicenter Acute Stroke Trial -Italy ( MAST - 1 ) Group | 1995 | Lancet1995，346，8989： | 1 |
| 16 | Supplemental therapeutic oxygen for prethreshold retinopathy of prematurity ( STOP-ROP ), a randomized, controlled trial I :Primary outcomes显示文摘 | The STOP-ROP Multicenter Study Group | 2000 | Pediatrics2000，105，2： | 1 |
| 17 | Efficacy of metformin in patients with non-insulin Vdependent diabetes mellitns显示文摘 | DeFronzo RA Goodman AM Multicenter Metformin Study Group | 1995 | N Engl J Med1995，333，9： | 1 |
| 18 | Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infection in the intensive care unit显示文摘 | Verwaest C Belgian Multicenter Study Group | 2000 | Clin Microbiol Infect2000，6，： | 1 |
| 19 | Clinical char- acteristics of bilirubin encephalopathy in Chinese newborn in- fants a national multicenter survey显示文摘 | Subspecialty Group of Neonatology Society of Pediatrics Chi- nese Medical Association Chinese Multicenter Study Coordina- tion Group for Neonatal gilirubin Eneephalopathy | 2012 | Zhonghua Er Ke Za Zhi2012，50，5： | 1 |
| 20 | Risk stratification and survival after myocardial infarction显示文摘 | Multicenter Postinfarctions Research Group | 1983 | N Engl J Med1983，309，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员