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| 1 | Early vs late endoscopic retrograde cholangiopancreatography in patients with acute cholangitis: A nationwide analysis显示文摘AIM To assess the effect of early vs late endoscopic retrograde cholangiopancreatography(ERCP) on mortality and readmissions in acute cholangitis, using a nationally representative sample.METHODS We used the 2014 National Readmissions Database to identify adult patients hospitalized with acute cholangitis who underwent therapeutic ERCP within one week of admission. Early ERCP was defined as ERCP performed on the same day of admission or the next day(days 0 or 1, < 48 h), and late ERCP was performed on days 2 to 7 of admission. Patients with severe cholangitis had any of the following additional diagnoses: Severe sepsis, septic shock, acute renal failure,acute respiratory failure, or thrombocytopenia. Multivariate logistic regression was used to calculate the adjusted odds of association of ERCP timing with inhospital mortality, 30-d mortality, and 30-d readmissions, controlling for age, sex,severe disease and comorbidities.RESULTS Four thousand five hundred and seventy patients satisfied the inclusion criteria;with a mean age of 64.1 years. Of these, 66.6% had early ERCP, while 33.4% had late ERCP. Early ERCP was associated with lower in-hospital mortality [1.2% vs2.4%, adjusted odds ratio(aOR) = 0.50, 95%CI: 0.76-0.83, P = 0.001] and lower 30-d mortality(1.5% vs 3.3%, aOR = 0.48, 95%CI: 0.33-0.69, P < 0.0001) compared to the late ERCP group. Similarly, early ERCP was associated with lower 30-d readmissions(9.7% vs 15.1%, aOR = 0.58, 95%CI: 0.49-0.7, P < 0.0001). When stratified by severity of cholangitis, there was a similar benefit of early ERCP on all outcomes in those with and without severe cholangitis. The mean length of stay was higher in the late ERCP group compared to the early ERCP group(6.9 d vs 4.5 d, P < 0.0001). The mean hospitalization cost was higher in the late ERCP group($21459 vs $16939, P < 0.0001).CONCLUSION Early ERCP is associated with lower in-hospital and 30-d mortality in those with or without severe cholangitis. Regardless of severity, we suggest performing early ERCP. | Ramzi Mulki Rushikesh Shah Emad Qayed | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，1： | 8 |
| 2 | Toxicological Studies on Ratanjyot Oil显示文摘 | GANDHI V M CHERIAN K M MULKY M J | 1995 | Food Chem Toxic1995，33，1： | 1 |
| 3 | Toxicological studies on Ratanjyot oil显示文摘 | Gandhi Cherian K M Mulky M J | 1995 | Food Chem Toxic1995，33，1： | 1 |
| 4 | Effects of Ethical Climate on Turnover Intention: Linking Attitudinal and Stress Theory显示文摘 | MULKI J P JARAMILLO J F LOCANDER W B | 2008 | Journal of Business Ethics2008，78，7： | 1 |
| 5 | Critical Role of Leadership on Ethical Climate and Salesperson Behaviors显示文摘 | MULKI J P JARAMILLO F J LOCANDER B W | 2009 | 86 (2) : 125-1412009，86，2： | 1 |
| 6 | A Meta-Analysis of the Relationship between Organizational Commitment and Salesperson Job Performance: 25 Years of Research 显示文摘 | Jaramillo F Mulki J P Marshall G W | 2005 | Journal of Business Research2005，58，6： | 1 |
| 7 | Set up remote workers to thrive显示文摘 | Mulki J Bardhi F Lassk F and Nanavaty-Dahl J | 2009 | MIT SloanManagement Review2009，，1： | 1 |
| 8 | Analysis of human immunodeficiency virus type 1 reverse transcriptase subunit structure/function in the context of infectious virions and human target cells 显示文摘 | Mulky A Kappes JC | 2005 | Antimicrob Agents Chemother2005，49，： | 1 |
| 9 | Antecedents of team creativity: an examination of team emotional in- telligence, team trust and collaborative culture creativi- ty and innovation management antecedents of team cre-ativity显示文摘 | BARCZAK G LASSK F MULKI J | 2010 | Creativity & Innovation Management2010，19，4： | 1 |
| 10 | A metaanalysis of the relationaship between organizational commitmentand salesperson job performance:25 years of research显示文摘 | FERNANDO J MULKI J P MARSHALL G W | 2005 | Journal of Business Research2005，58，： | 1 |
| 11 | Subunitspecific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo 显示文摘 | Mulky A Sarafianos SG Arnold E | 2004 | J Virol2004，78，： | 1 |
| 12 | Toxicological dtudies on ratanjyot oil显示文摘 | Gandhi V M Cherian K M Mulky M J | 1995 | Food Chem Toxicol1995，33，1： | 1 |
| 13 | Analysis of amino acids in the β7-β8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in Virus Replication显示文摘 | ALOK MULKY CHRISTIE VU B CONWAY JOAN A | 2007 | J Mol Biol2007，365，5： | 1 |
| 14 | Antecedents of Team Creativity: An Examination of Team Emotional Intelligence, Team Trust and Collaborative Culture 显示文摘 | Gloria Barczak Felicia Lassk &Jay Mulki | 2010 | Creativity & Innovation Management2010，19，4： | 1 |
| 15 | Toxicological studies onratanjyot oil 显示文摘 | Gandhi V M Cherian K M Mulky M J | 1995 | Food Chem Toxicol1995，33，1： | 1 |
| 16 | A Meta-Analysis of the Re-lationship Between Organizational Commitment and Salesperson JobPerformance:25 Years of Research显示文摘 | Jaramillo F Mulki J P Marshal G W L | 2005 | Journal of Business Re-search2005，58，6： | 1 |
| 17 | Ethical reputation and value received: customer perceptions 显示文摘 | Jay Prakash Mulki Fernando Jaramillo | 2011 | International Journal of Bank Marketing2011，29，5： | 1 |
| 18 | Toxicological studies on Ratanjyot oil显示文摘 | Gandhi V M Cherian K M Mulky M J | 1995 | Food Chemistry1995，33，1： | 1 |
| 19 | Toxicological studies on Ratanjyot oil显示文摘 | Gandhi V M Cherian K M Mulky M J | 1995 | Food Chem Toxic1995，33，1： | 1 |
| 20 | Antecedents of team creativity: an examination of team emotional interlli- gence, team trust and collaborative culture creativity and innovation management antecedents of team creativity 显示文摘 | Barczak G Lassk F Mulki J | 2010 | Creativity & Innovation Management2010，19，4： | 1 |
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