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您的检索式：作者名="Muhammad S.Ali"
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| 1 | Nanocellulose isolation characterization and applications:a journey from non-remedial to biomedical claims显示文摘Cellulose is a renewable,biodegradable,ecofriendly and sustainable biomaterial.Global market of nanocellulose is comprehensively very high due to its utility.Extraction of nanocellulose from bacteria and plant results in different morphology and size of nanocellulose.Biocompatibility,mechanical strength,biofabrication,crystallinity,high surface area per unit mass,hydrophilicity,porosity,transparency and non-toxicity of bacterial cellulose make it more attractive.The extravagant nanoscaled three-dimensional network of cellulosic structures possess extraordinary properties for biomedical application,evidencing its usage in skin therapy,cardiovascular implants,cartilage meniscus implants,tissue engineering,bone tissue and neural implants,wound care products,drug delivery agents,tablet modification,tissue engineered urinary conduits,and synthesis of artificial cornea.Hence due to potential benefits associated with nanocellulose effective and efficient techniques are required for the isolation of nanocellulose that should be economical,ecofriendly and non-toxic. | Sania Naz Joham S.Ali Muhammad Zia | 2019 | Bio-Design and Manufacturing2019，2，3： | 1 |
| 2 | Synthesis,Urease Inhibition and Molecular Modelling Studies of Novel Derivatives of the Naturally Occurring b-Amyrenone显示文摘Urease enzyme(UE)has been reported to be a potent virulence factor for Helicobacter pylori(HP)bacteria indicated to be responsible for various gastrointestinal diseases.Therefore,the spread of HP,currently regarded by the World Health Organization as a class 1 carcinogen,could be better controlled by targeting UE.It is in this line that we have synthesized three new derivatives(2–4)of the naturally occurring olean-12-en-3-one(1),which was previously isolated from the figs of Ficus vallis-choudae Delile(Moraceae).Among the synthesized compounds,3 and 4 contain an indole moiety.Their structures were unambiguously assigned by spectroscopic and spectrometric techniques(1D-NMR,2D-NMR and MS).The starting material and the synthesized compounds were screened for UE inhibition activity,and showed significant activities with IC50 values ranging from 14.5 to 24.6 lM,with compound(1)being the most potent as compared to the positive control thiourea(IC50=21.6 lM).Amongst the synthetic derivatives,compound 4 was the most potent(IC50-=17.9 lM),while the others showed activities close to that of the control.In addition,molecular docking study of target compounds 2–4 was performed in an attempt to explore their binding mode for the design of more potent UE inhibitors. | Jean J.K.Bankeu Hira Sattar Yannick S.F.Fongang Syeda W.Muhammadi Conrad V.Simoben Fidele Ntie-Kang Guy R.T.Feuya Marthe A.T.Tchuenmogne Mehreen Lateef Bruno N.Lenta Muhammad S.Ali Augustin S.Ngouela | 2019 | Natural Products and Bioprospecting2019，9，1： | 0 |
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