3篇
您的检索式：作者名="Muhammad H.Maqsood"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The dilemma of cytomegalovirus and hepatitis B virus interaction显示文摘Hepatitis B virus(HBV)remains a global public health problem despite the availability of effective vaccine and antiviral therapy.Cytomegalovirus(CMV),another hepatotropic virus,is also very prevalent in the general population worldwide.Both HBV and CMV can persist in the host and have potential to reactivate especially with weakened host cellular immunity.Superimposed CMV infection can lead to severe HBV reactivation.The pathogenesis of the co-infection of HBV and CMV remains poorly understood.Studies reported conflicting results regarding the inhibitory effect of CMV on HBV replication.There is an unmet need on the management of co-infection of HBV and CMV;research initiatives dedicated to understanding their interactions are urgently needed. | Muzammil M.Khan Mukarram J.Ali Hira Hanif Muhammad H.Maqsood Imama Ahmad Javier E.G.Alvarez Maria-Andreea Catana Daryl T.Y.Lau | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 2 | 强化甲肝/乙肝疫苗方案对于慢性丙型肝炎患者是必要的显示文摘Introduction Hepatitis C virus(HCV)is a major cause of chronic liver diseases.Hepatitis A virus(HAV)or hepatitis B virus(HBV)infection on pre-existing hepatitis C can lead to significant morbidity and mortality[1].The Advisory Committee on Immunization Practices(ACIP)recommends HAV and HBV vaccination for patients with chronic liver diseases[2,3].Best-practice advice from the American College of Physicians and the Centers for Disease Control and Prevention(CDC)also emphasized the importance of HBV vaccination for at-risk populations[4].The hepatitis B vaccine response,however,is generally lower among patients with chronic liver diseases,especially those with cirrhosis or older age[5,6].In this study,we reported that a high proportion of patients with chronic hepatitis C remained at risk of HAV or HBV infection at their referral to our tertiary Liver Center. | Muhammad H.Maqsood Himabindu Kolli Satinder P.Kaur Karen J.Campoverde Reyes Javier Guevara Pir A.Shah Arslan Talat Daryl T.Y.Lau | 2020 | Gastroenterology Report2020，8，4： | 0 |
| 3 | 一例慢性乙肝患者甲胎蛋白检测结果的差异所带来的挑战显示文摘Introduction Alpha-fetoprotein(AFP)is the most abundant serum protein found in the human fetus,produced by the yolk sac and the liver[1].The levels of maternal serum AFP reach a peak value at28-32 weeks of gestation and decrease rapidly after birth and usually drop to the normal at 8-12 months of age.The normal serum AFP level for an adult is<20 ng/mL[2].In contrast,livertumor cells usually synthesize and secrete an increased level of AFP.Abdominal ultrasound and AFP are generally recommended as the screening modality for HCC for patients at risk for development of hepatocellular carcinoma(HCC)[1].AFP-L3,an isoform of AFP that binds Lens culinaris agglutinin,can be particularly useful in the early identification of aggressive HCC[2].These assays,however,can generate false-positive and false-negative AFP values.Of patients with advanced HCC,20%had normal AFP levels,whereas some patients with liver diseases had significant AFP elevation without liver cancer in long-term surveillance[3].Elevated AFP levels could be associated with active liver diseases with hepatocyte regeneration[4,5].In that setting,the AFP level will decline with improvement of the underlying liver condition.Our case illustrated the dilemma and uncertainties as a result of persistent abnormal AFP values after extensive clinical investigations. | Pir A.Shah Allison Onken Rizwan Ishtiaq Muhammad H.Maqsood Shyam S.Patel Karen J.Campoverde Reyes Adrianna Z.Herskovits Daryl T.Y.Lau | 2020 | Gastroenterology Report2020，8，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员