| 1 | Development of 19-plex Y STR system and polymorphism studies in Pakistani population显示文摘For the development of 19-plex Y STR system and polymorphism studies in local ethnic populations sixteen markers of non-recombining regions (NRY) of Y chromosome, which show high power of discrimination among individuals, were selected in this study. Blood samples (600) were collected from the males of three most common castes of Pakistani population (Arain, Awan and Rajput) with different parent lineages. Three markers (DYS385a/b, DYS389I/II and YCAIIa/b) among 16 Y STRs are double-targeted regions of the Y chromosome and thus provide two polymorphic peaks for each respective primer set. These 16 Y-STRs were developed into Megaplex system for simultaneous amplification of all markers within the population. The overall power of discrimination observed in focused populations was 60.5%, 66.5% and 55% in Rajput, Awan and Arain casts respectively. This discrimination power will be helpful in human identification for forensic casework studies including sexual assaults and paternity testing. | Faraz Malik Mahmood A. Kayani M. Ansar Obaid Ullah Muhammad Shafeeq Shahid Chohan Yassir Abbas Saqib Shazad Ali Raza Rahat Rehman Faizan Raiz Qurat-ul-ain Muhammad Hassan Siddiqi Allah Rakha Zia ur Rehman Zahoor Ahmed | 2008 | Journal of Pharmaceutical Analysis2008，20，4： | 0 |
| 2 | Insecticidal Potential of α-Pinene and β-Caryophyllene against Myzus persicae and Their Impacts on Gene Expression显示文摘Myzus persicae(M.persicae)is now considered a threat to agricultural crops due to economic losses.Numerous synthetic insecticides applied every year against M.persicae,are reported to be unsafe for environment,humans,and beneficial insects.Furthermore,several species of Myzus have been found to develop resistance due to over application of these insecticides.Therefore,it is required to find some novel insecticide that would be safe for the environment as well as for humans.In the current study,two major pure constituentsα-pinene andβ-caryophyllene were evaluated for their insecticidal potential against M.persicae using a fumigant toxicity assay.Furthermore,impact ofα-pinene andβ-caryophyllene on expression of five different genes,e.g.,HSP 60,FPPS I,OSD,TOL and ANT responsible for reproduction,dispersion,and growth of M.persicae has also been investigated.To perform fumigant toxicity assay,five different concentrations(3.5,4,4.5,5 and 6μL L−1)ofα-pinene andβ-caryophyllene were prepared.Lethal concentration(LC)was calculated,and gene expression studies were executed through qRT PCR at LC30 ofα-pinene andβ-caryophyllene.Both constituents demonstrated excellent fumigant toxicity effects against M.persicae at all five concentrations.However,α-pinene shows significantly better results(98%)as compared toβ-caryophyllene(80%)after 72 h at 6μL L−1 of dose.The highest upregulation in expression was demonstrated at LC30 dose ofα-pinene in five in three out of five genes understudy(TOL,ANT,and FPPS I).Conversely,two genes HSP 60 and OSD demonstrated downregulation at LC30 dose ofβ-caryophyllene.Conclusively,our results highlighted the promising insecticidal potential of both compoundsα-pinene andβ-caryophylleneby interfering with the reproduction and development related processes in M.persicae,allowing us to recommend the phytoconstituents under investigation as an ecofriendly alternative to synthetic insecticides. | Talha Ali Chohan Tahir Ali Chohan Muhammad Zahid Mumtaz Muhammad Waqar Alam Salah ud Din Iqra Naseer Ayesha Riaz Tayyeba Naseem Areeba Iftikhar Dur ENajaf Ali Mubashir Hassan Hayssam M.Ali | 2023 | Phyton-International Journal of Experimental Botany2023，92，7： | 0 |
| 3 | Evaluating the exchange rate and commodity price nexus in Malaysia: evidence from the threshold cointegration approach显示文摘This paper examines the long-and short-run dynamics of asymmetric adjustment between the nominal exchange rate and commodity prices,namely oil,palm oil,rubber,and natural gas prices,in Malaysia using monthly data from January 1994 to December 2017.The relationship between exchange rate and each commodity price is examined in terms of Engle-Granger and threshold cointegrations.The estimated results provide evidence of long-run threshold cointegration and show that the adjustments towards the long-run equilibrium position are asymmetric in the short run.Furthermore,this study finds evidence of a unidirectional causal relationship running from the nominal exchange rate to oil price in the long and short run using a spectral frequency domain causality application.There is also empirical evidence of bidirectional causality between the nominal exchange rate and palm oil price,rubber price,and natural gas price in the long and short run.Overall,the findings have significant implications for the current debate on the future of primary commodities in Malaysia. | Shamaila Butt Suresh Ramakrishnan Nanthakumar Loganathan Muhammad Ali Chohan | 2020 | Financial Innovation2020，6，1： | 0 |
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