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2篇 您的检索式：作者名="Mu Renwang"

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		题名	作者	年代	出处	被引量
	1	Generation ofone-or two-dimensional arrays of hollow optical microtrapsfor cold atoms, molecules, or microparticles on a chip显示文摘	Mu Renwang Lu Junfa Xu Shuwu	2009	Journal of the Optical Society of America B2009，26，1：	1
	2	Crystal structures, absolute configurations and molecular docking studies of naftopidil enantiomers as α1D-adrenoceptor antagonists显示文摘Chiral drug naftopidil(NAF), a specific α1D-adrenoceptor(AR) antagonist for the treatment of benign prostatic hyperplasia, was used in racemic form for several decades. Our recent work declared that NAF enantiomers showed the same antagonistic effects on the α1D-AR, but the binding mechanism of these two stereochemical NAF isomers to the α1D receptor remained unclear. Herein, we reported the crystallographic structures of optically pure NAF stereoisomers for the first time and unambiguously determined their absolute configurations. The crystal data of R and S enantiomers matched satisfactorily the pharmacophore model for α1D-selective antagonists. Based on the constructed α1D homology model,molecular docking studies shed light on the molecular mechanism of NAF enantiomers binding to α1D-AR. The results indicated that NAF enantiomers exhibited the very similar binding poses and occupied the same binding pocket.	Wei Xu Junjun Huang Renwang Jiang Mu Yuan	2017	Acta Pharmaceutica Sinica B2017，7，4：	0

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