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| 1 | Perioperative anemia management in colorectal cancer patients:A pragmatic approach显示文摘Anemia,usually due to iron deficiency,is highly prevalent among patients with colorectal cancer.Inflammatory cytokines lead to iron restricted erythropoiesis further decreasing iron availability and impairing iron utilization.Preoperative anemia predicts for decreased survival.Allogeneic blood transfusion is widely used to correct anemia and is associated with poorer surgical outcomes,increased post-operative nosocomial infections,longer hospital stays,increased rates of cancer recurrence and perioperative venous thromboembolism.Infections are more likely to occur in those with low preoperative serum ferritin level compared to those with normal levels.A multidisciplinary,multimodal,individualized strategy,collectively termed Patient Blood Management,minimizes or eliminates allogeneic blood transfusion.This includes restrictive transfusion policy,thromboprophylaxis and anemia management to improve outcomes.Normalization of preoperative hemoglobin levels is a World Health Organization recommendation.Iron repletion should be routinely ordered when indicated.Oral iron is poorly tolerated with low adherence based on published evidence.Intravenous iron is safe and effective but is frequently avoided due to misinformation and misinterpretation concerning the incidence and clinical nature of minor infusion reactions.Serious adverse events with intravenous iron are extremely rare.Newer formulations allow complete replacement dosing in 15-60 min markedly facilitating care.Erythropoiesis stimulating agents may improve response rates.A multidisciplinary,multimodal,individualized strategy,collectively termed Patient Blood Management used to minimize or eliminate allogeneic blood transfusion is indicated to improve outcomes. | Manuel Muoz Susana Gómez-Ramírez Elisa Martín-Montaez Michael Auerbach | 2014 | World Journal of Gastroenterology2014，20，8： | 8 |
| 2 | Intravenous iron in inflammatory bowel disease显示文摘The prevalence of anemia across studies on patients with inflammatory bowel disease (IBD) is high (30%). Both iron defi ciency (ID) and anemia of chronic disease contribute most to the development of anemia in IBD. The prevalence of ID is even higher (45%). Anemia and ID negatively impact the patient's quality of life. Therefore, together with an adequate control of disease activity, iron replacement therapy should start as soon as anemia or ID is detected to attain a normal hemoglobin (Hb) and iron status. Many patients will respond to oral iron, but compliance may be poor, whereas intravenous (IV) compounds are safe, provide a faster Hb increase and iron store repletion, and presents a lower rate of treatment discontinuation. Absolute indications for IV iron treatment should include severe anemia, intolerance or inappropriate response to oral iron, severe intestinal disease activity, or use of an erythropoietic stimulating agent. Four different products are principally used in clinical practice, which differ in their pharmacokinetic properties and safety profi les: iron gluconate and iron sucrose (lower single doses), and iron dextran and ferric carboxymaltose (higher single doses). After the initial resolution of anemia and the repletion of iron stores, the patient's hematological and iron parameters should be carefully and periodically monitored, and maintenance iron treatment should be provided as required. New IV preparations that allow for giving 1000-1500 mg in a single session, thus facilitating patient management,provide an excellent tool to prevent or treat anemia and ID in this patient population, which in turn avoids allogeneic blood transfusion and improves their quality of life. | Manuel Muoz Susana Gómez-Ramírez José Antonio García-Erce | 2009 | World Journal of Gastroenterology2009，15，37： | 2 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Variant selection of primary, secondary and tertiary twins in a deformed Mg alloy显示文摘 | Sijia Mu John J. Jonas Günter Gottstein | 2012 | Acta Materialia2012，，5： | 2 |
| 5 | Thermal boundary resistance and temperature dependent phonon conduction in CNT array muhilayer structure显示文摘 | WANG Z L MU H T LIANG J G | 2013 | Int J Thermal Sciences2013，74，： | 1 |
| 6 | Larger Acoustic Band Gaps Obtained by Configurations of Rods in Two-dimensional Phononic Crystals显示文摘 | Xu Z L Wu F G Mu Z F | 2007 | Journal of Physics D :Applied Physics2007，40，： | 1 |
| 7 | Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients 显示文摘 | Mu U Kyte JA Kvalheim G Aamdal S | 2005 | Br J Cancer2005，93，7： | 1 |
| 8 | Damage detection of reinforced concrete beams with novel distributed crack/strain sensors 显示文摘 | Chen G Mu H M | 2004 | Structural Health Monitoring2004，3，3： | 1 |
| 9 | Baicalein exerts neuroprotectire effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro显示文摘 | Mu X He G R Cheng Y X | 2009 | Pharmacol Biochem Behav2009，92，4： | 1 |
| 10 | The formation of wormlike micelles in anionic surfactant aqueous solutions in the presence of bivalent counterion 显示文摘 | MU J H LI G Z | 2001 | Chemical Physics Letters2001，345，12： | 1 |
| 11 | Which ornamental plant species effectively remove benzene from indoor air 显示文摘 | Liu Y J Mu Y J Zhu Y G | 2007 | Atmospheric Environment2007，41，： | 1 |
| 12 | Preparation,characterization and aggregation behave-or of amphiphilic chitosan derivative having poly(L-lactic acid) side chains显示文摘 | Li G Zhuang YL Mu Q etal | 2008 | Carbohydrate Polymers2008，72，： | 1 |
| 13 | Transplantation of induced bone marrow mesenchymal stem cells improves the cardiac function of rabbits with dilated cardiomyopathy via upregulation of vascular endothelial growth factor and its receptors显示文摘 | Mu Y Cao G Zeng Q | 2011 | Exp Biol Med(Maywood)2011，236，9： | 1 |
| 14 | A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses sex prophenoloxidase genes 显示文摘 | Mu ller H M Dimopoulos G Blass C | 1999 | J Biol Chem1999，274，11： | 1 |
| 15 | Survivin-an attractive target for RNAi in non-Hodgkin' s lymphoma Daudi cell line as a model 显示文摘 | Congmin G Mu Z Yihui M | 2006 | Leuk Lymphoma2006，47，9： | 1 |
| 16 | Effect of metallic cations on corrosion inhibition of an anionic surfactant 显示文摘 | Mu G N Zhao T P Liu M | 1996 | Corrosion1996，52，： | 1 |
| 17 | Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes 显示文摘 | Mu J Petrov A Eiermann G J | 2009 | European Journal of Pharmacology2009，623，123： | 1 |
| 18 | Energy and exergy efficiencies in the Chinese transportation sector, 1980 - 2009 显示文摘 | Zhang M Li G Mu H L | 2011 | Energy2011，36，2： | 1 |
| 19 | Leakage resilient authenticated key exchange secure in the auxiliary input model显示文摘 | Yang G Mu Y Susilo W | 2013 | Information Security Practice and Experience2013，，7863： | 1 |
| 20 | Synthesis of PZT nanocrystalline powder by a modified sol-gel process using water as primary solvent source显示文摘 | MU G H YANG S Y LI J F | 2007 | J Mater Process Technol2007，182，13： | 1 |
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