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| 1 | Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon显示文摘AIM To assess the burden of norovirus(No V) and to determine the diversity of circulating strains among hospitalized children in Lebanon. METHODS Stool samples were collected from children presenting with acute gastroenteritis to six major hospitals in Lebanon. A total of 739 eligible stool samples, testing negative for diarrhea caused by rotavirus as a possible viral pathogen, were collected between January 2011 and June 2013. A standardized questionnaire including demographic, epidemiological and clinical observations was used at the time of hospitalization of children presenting with diarrhea. Viral RNA was extracted from stool samples followed by reverse transcription polymerase chain reaction and nucleotide sequencing of a fragment of the viral protein 1 capsid gene. Multiple sequence alignments were carried out and phylogenetic trees were constructed using the MEGA 6 software.RESULTS Overall, 11.2% of stool samples collected from children aged < 5 years tested positive for No V genogroups Ⅰ(GⅠ) and Ⅱ(GⅡ). GⅡ accounted for 10.6% of the gastroenteritis cases with only five samples being positive for GⅠ(0.7%). The majority of hospitalized children showed symptoms of diarrhea, dehydration, vomiting and fever. Upon sequencing of positive samples and based on their clustering in the phylogenetic tree, 4/5 of GⅠ gastroenteritis cases were designated GⅠ.3 and one case as GⅠ.4. GⅡ.4 was predominantly detected in stool of our study participants(68%). We report a JB-15/KOR/2008 GⅡ.4 Apeldoorn 2008-like variant strain circulating in 2011; this strain was replaced between 2012 and 2013 by a variant sharing homology with the Sydney/NSW0514/2012/AUS GⅡ.4 Sydney 2012 and Sydney 2012/FRA GⅡ.4 strains. We also report the co-circulation of non-GⅡ.4 genotypes among hospitalized children. Our data show that No V gastroenteritis can occur throughout the year with the highest number of cases detected during the hot months.CONCLUSION The majority of No V-associated viral gastroenteritis cases among our participants are attributable to GⅡ.4, which is compatible with results reported worldwide. | Nada M Melhem Hassan Zaraket Khalil Kreidieh Zeinab Ali Moza Hammadi Soha Ghanem Farah Hajar Amjad Haidar Adlette Inati Mariam Rajab Hassan Fakhouri Bassam Ghanem Ghassan Baasiri Ghassan Dbaibo | 2016 | World Journal of Gastroenterology2016,22,48: | 3 |
| 2 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna(Tbunnus albacares)显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,2: | 1 |
| 3 | The effects on the microbiological condition of product of carcass dressing, cooling, and portioning processes at a poultry packing plant 显示文摘 | Gill C O Moza L F Badoni M | 2006 | International Journal of Food Microbiology2006,110,2: | 1 |
| 4 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna(Thunnus albacares)显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,: | 1 |
| 5 | Characterization of mouse MyoTilin and its promoter 显示文摘 | MOLOGNI L MOZA M LALOWSKI M M | 2005 | Biochem Bioph Res Co2005,329,: | 1 |
| 6 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna (Thunnus a!bacares)显示文摘 | Nejib G Moza A A Ismail M A at al | 2005 | Food Research International2005,38,: | 1 |
| 7 | The effect of storage temperature on histamine product on and the fresh- ness of yellow fin tuna ( Thunnus albacares) 显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,2: | 1 |
| 8 | Term structure of 4d-electron configurations and calculated spectrum in Sn-isonuclear sequence显示文摘 | Al-Rabban | 2006 | JQSRT2006,97,: | 1 |
| 9 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna(Thunnus albacores)显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,: | 1 |
| 10 | The effects on the microbiological condition of product of carcass dressing, cooling and portioning processes at a poultry plallt显示文摘 | GILL C O MOZA L F BADONI M | 2006 | International Journal of Food Microbiology2006,110,: | 1 |
| 11 | The proline-rich protein palladin is a binding partner for profilin显示文摘 | Boukhelifa M Moza M Johansson T | 2006 | FEBS J2006,273,1: | 1 |
| 12 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna (Thunnus albacares)显示文摘 | NEJIB G MOZA A A ISMAIL M A | 2010 | Food Research International2010,38,2: | 1 |
| 13 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna (Thunnus albacares)显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,2: | 1 |
| 14 | The effect of storage temperature on histamine production and the freshness of yellow fin tuna (Thunnus albacares)显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,3: | 1 |
| 15 | Factorial experimental design of winery wastewaters treatment by heterogeneous photoFenton process显示文摘 | Mosteo R Ormad M P Mozas E | 2006 | Water Res2006,40,8: | 1 |
| 16 | The effect of storage temperature on histamine production and the freshness of yellowfin tuna( Thunnus albacares) 显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,: | 1 |
| 17 | Glycated albumin, a precursor of advanced glycation end-products, up-regulates NADPH oxidase and enhances oxidative stress in human endothelial ceils : molecular correlate of diabetic vas- culopathy显示文摘 | RODINO-JANEIRO B K GONZ6LEZ-PETEIRO M UCIEDA-SO- MOZA R | 2010 | Diabetes Metab Res Rev2010,26,7: | 1 |
| 18 | The effect of storage temperature on histamine production and the freshness of yellow fin tuna (Thunnus albacares) 显示文摘 | Nejib G Moza A A Ismail M A | 2005 | Food Research International2005,38,: | 1 |